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Development of Signal Processing Modules for Double-sided Silicon Strip Detector of Gamma Vertex Imaging for Proton Beam Dose Verification
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 Title & Authors
Development of Signal Processing Modules for Double-sided Silicon Strip Detector of Gamma Vertex Imaging for Proton Beam Dose Verification
Lee, Han Rim; Park, Jong Hoon; Kim, Jae Hyeon; Jung, Won Gyun; Kim, Chan Hyeong;
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 Abstract
Recently, a new imaging method, gamma vertex imaging (GVI), was proposed for the verification of in-vivo proton dose distribution. In GVI, the vertices of prompt gammas generated by proton induced nuclear interaction were determined by tracking the Compton-recoiled electrons. The GVI system is composed of a beryllium electron converter for converting gamma to electron, two double-sided silicon strip detectors (DSSDs) for the electron tracking, and a scintillation detector for the energy determination of the electron. In the present study, the modules of a charge sensitive preamplifier (CSP) and a shaping amplifier for the analog signal processing of DSSD were developed and the performances were evaluated by comparing the energy resolutions with those of the commercial products. Based on the results, it was confirmed that the energy resolution of the developed CSP module was a little lower than that of the CR-113 (Cremat, Inc., MA), and the resolution of the shaping amplifier was similar to that of the CR-200 (Cremat, Inc., MA). The value of representing the magnitude of noise of the developed system was estimated as 6.48 keV and it was confirmed that the trajectory of the electron can be measured by the developed system considering the minimum energy deposition ( > ~51 keV) of Compton-recoiled electron in 145--thick DSSD.
 Keywords
Proton therapy;Dose verification;Prompt gamma;Gamma vertex imaging;Double-sided silicon strip detector;Signal processing system;
 Language
Korean
 Cited by
1.
Prototype system for proton beam range measurement based on gamma electron vertex imaging, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2017, 857, 82  crossref(new windwow)
2.
Development of Dual-mode Signal Processing Module for Multi-slit Prompt-gamma Camera, Progress in Medical Physics, 2016, 27, 1, 37  crossref(new windwow)
3.
Monitoring 3D dose distributions in proton therapy by reconstruction using an iterative method, Applied Radiation and Isotopes, 2016, 114, 33  crossref(new windwow)
4.
Validation of energy-weighted algorithm for radiation portal monitor using plastic scintillator, Applied Radiation and Isotopes, 2016, 107, 160  crossref(new windwow)
 References
1.
Schardt D, Elsasser T, Schulz-Ertner D. Heavy-ion tumor therapy: Physical and radiobiological benefits. Rev. Mod. Phys. 2010;82:383-425. crossref(new window)

2.
Wilson RR. Radiological. use of fast protons. Radiology. 1946;47:487-491. crossref(new window)

3.
PTCOG patient statistics of particle therapy centers per end of 2012. http://ptcog.web.psi.ch/Archive/pat_statistics/Patientstatistics-updateMar2013.pdf.

4.
Paganetti H. Range uncertainties in proton therapy and the role of Monte Carlo simulations. Phys. Med. Biol. 2012;57:R99-R117. crossref(new window)

5.
Lu HM. A point dose method for in vivo range verification in proton therapy. Phys. Med. Biol. 2008;53:N415-N422. crossref(new window)

6.
Knopf AC. Lomax A. In vivo proton range verification: a review. Phys. Med. Biol. 2012;58:R131-R160.

7.
Min CH, Kim CH, Youn MY, Kim JW. Prompt gamma measurements for locating the dose fall-off region in the proton therapy. Appl. Phys. Lett. 2006;89:183517. crossref(new window)

8.
Min CH, Lee HR, Lee SB, Kim CH. Development of array-type prompt gamma measurement system for in vivo range verification in proton therapy. Med. Phys. 2012;39:2100-2107. crossref(new window)

9.
Lee HR, Park JH, Kim HS, Kim CH. Two- dimensional measurement of the prompt-gamma distribution for proton dose distribution monitoring. J. Korean Phys. Soc. 2012;61:1385-1389 crossref(new window)

10.
Bom V, Joulaeizadeh L, Beekman F. Real-time prompt gamma monitoring in spot-scanning proton therapy using imaging through a knife- edgeshaped slit. Phys. Med. Biol. 2012;57:297-308. crossref(new window)

11.
Smeets J, Roellinghoff F, Prieels D, Stichelbaut F, Benilov A, Busca P, Fiorini C, Peloso R, Basilavecchia M, Frizzi T, Dehaes JC, Dubus A. Prompt gamma imaging with a slit camera for real- time range control in proton therapy. Phys. Med. Biol. 2012;57:3371-3405. crossref(new window)

12.
Mackin D, Peterson S, Beddar S, Polf J. Evaluation of a stochastic reconstruction algorithm for use in Compton camera imaging and beam range verification from secondary gamma emission during proton therapy. Phys. Med. Biol. 2012;57:3537-3553. crossref(new window)

13.
Kurosawa S, Kubo H, Ueno K, Kabuki S, Iwaki S, Takahashi M, Taniue K, Higashi N, Miuchi K, Tanimori T, Kim D, Kim J. Prompt gamma detection for range verification in proton therapy. Curr. Appl. Phys. 2012;12:364-368. crossref(new window)

14.
Kim CH, Park JH, Seo H, Lee HR. Gamma electron vertex imaing and application to beam range verification in proton therapy. Med. Phys. 2012;39: 1001-1005 crossref(new window)

15.
Thomas SL, Davinson T, Shotter AC. A modular amplifier system for the readout of silicon strip detectors. Nucl. Instrum. Meth. A. 1990;288:212-218. crossref(new window)