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A Study on Mice Exposure Dose for Low-dose Gamma-irradiation Using Glass Dosimeter
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 Title & Authors
A Study on Mice Exposure Dose for Low-dose Gamma-irradiation Using Glass Dosimeter
Noh, Sung Jin; Kim, Hyo Jin; Kim, Hyun; Jeong, Dong Hyeok; Son, Tae Gen; Kim, Jung Ki; Yang, Kwangmo; Nam, Sang-Hee; Kang, Yeong-Rok;
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 Abstract
The low dose radiation is done for a long period, thus researchers have to know the exact dose distribution for the irradiated mouse. This research has been conducted in order to find out methods in transmitting an exact dose to mouse in a mouse irradiation experiment carried out using irradiation equipment installed in the DIRAMS (Dongnam Institution of Radiological & Medical Sciences) research center. We developed a single mouse housing cage and shelf with adjustable geometric factors such as distance and angle from collimator. The measurement of irradiated dose showed a maximal 42% difference of absorbed dose from the desired dose in the conventional irradiation system, whereas only 6% difference of the absorbed dose was measured in the self-developed mouse apartment system. In addition, multi mice housing showed much difference of the absorbed dose in between head and body, compared to single mouse housing in the conventional irradiation system. This research may allow further research about biological effect assessment for the low dose irradiation using the self-developed mouse apartment to provide more exact doses which it tries to transmit, and to have more reliability for the biological analysis results.
 Keywords
Low dose irradiation;Quality assurance;Self-developed mouse apartment system;Dose assessment;Glass dosimeter;
 Language
Korean
 Cited by
 References
1.
Olivieri G, Bodycote J, Wolff S. Adaptive response of human lymphocytes to low concentrations of radioactive thymidine. Science. 1984; 223:594-7. crossref(new window)

2.
Sankaranarayanan K, Dyn AV, Loos M. J, Natarajan A. T. Adaptive response of human lymphocytes to low-level radiation from radioisotope or X-rays. Mutat Res. 1989;211: 7-12. crossref(new window)

3.
Di Chen. Measurement of depth doses in rat and mouse phantoms exposed to $^{252}Cf$ mixed neutron and gamma radiation, J Radiat Res. 1988;29(1): 119-129. crossref(new window)

4.
Zoetelief J. Recent EULEP dosimetry intercomparisons for whole body irradiation of mice. European Late Effects Project group, Int J Radi Biol. 1997;72(5): 627-632.

5.
Yeong-Rok Kang, Tae Gen Son, Kwangmo Yang, Dong Hyeok Jeong, Manwoo Lee, Sung Jin Noh. A Shelf of Irradiation Apparatus, Korea parent application number KR 10-2014-0109827.

6.
Jennie Treleaven, Andrew Gennery, Judith Marsh, Derek Norfolk, Lizanne Page, Anne Parker, Frank Saran, Jim Thurston, David Webb. Guidelines on the use of irradiated blood components prepared by the British Committee for Standards in Haematology blood transfusion task force, 2011;152:35-51. British Journal of Haematology. crossref(new window)

7.
Piesch E, Burgkhardt B, Vilgis M. Photoluminescence dosimetry: Progress and present state of art, Radiat Prot Dosim. 1990;33:215-216.

8.
Tsuda M. A few remarks on photoluminescence dosimetry with high energy x-ray, Jpn J Med. 2000;20:131-139.

9.
Technical Report. Explanation material of RPL glass dosimeter. Small element system, Asahi Techno Glass Corporation, Tokyo, Japan. 2000.

10.
Hoshi Y, Nomura T, Oda T, Iwasaki T, Fujita K, Ishikawa T, Kato A, Ikegami T, Sakai K, Tanooka H, Yamada T. Application of a newly developed photoluminescence glass dosimeter for measuring the absorbed dose in individual mice exposed to low-dose rate $^{137}Cs$ $\tau$-rays, J Radiat Res. 2000;41: 129-137. crossref(new window)

11.
Zhuo W, Liu W, Huang G, Zhu G, Ma, G. Comparison of dosimetric properies between GD-300 series of radiophotoluminescent glass detectors and GR-200 series of thermoluminescent detectors, Nucl. Sci. Tech. 2007;18:362-365. crossref(new window)

12.
Shih-Ming Hsu, Hsi-Wen Yang, Tien-Chi Yeh, Wei-Lin Hsu, Chin-Hui Wu, Chin- Chang Lu, Wei-Li Chen, David Y.C. Huang. Synthesis and physical characteristics of rad photoluminescent dosimeters, Radiat. Meas. 2007;42:621-624. crossref(new window)

13.
Kazuo Sakai, Takaharu Nomura, Yasuhiro Ina. Enhancement of bio-protective functions by low dose/dose-rate radiation, Dose-Response. 2006; 4(4):327-332. crossref(new window)

14.
Yasuhiro Ina, Hiroshi Tanooka. Suppression of Thymic Lymphoma Induction by Life-Long Low- Dose Rate Irradiation Accompanied by Immune Activation in C57BL/6 Mice, Radiation Research. 2005;163:153-158. crossref(new window)