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Inhibitory effect of mushrooms extract on TNF-α/INF-γ induced-cytokine in human keratinocytes, HaCaT
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  • Journal title : Journal of Mushroom
  • Volume 13, Issue 3,  2015, pp.170-174
  • Publisher : The Korean Society Of Mushroom Science
  • DOI : 10.14480/JM.2015.13.3.170
 Title & Authors
Inhibitory effect of mushrooms extract on TNF-α/INF-γ induced-cytokine in human keratinocytes, HaCaT
Choi, Eun-Ju; Kim, Eun-Kyung; Ji, Yong-Seok; Lee, Chang-Jin;
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Mushroom is known for anti-inflammatory and anti-oxidative potential. This study provides evidence that the inhibitory effect of mushroom on the expression of pro-inflammatory cytokines in human keratinocytes, HaCaT cells. To define the underlying mechanisms of action, tumor necrosis factor/-activated human keratinocytes model was used. Mushroom significantly inhibited the expression of cytokines in HaCaT cells. Taken together, the results demonstrate that mushroom inhibited inflammtion, suggesting that mushroom (DW extract: Grifola frondosa Cordyceps militaris), (Ethanol extract: Ganoderma lucidum, Lentinus edodes, Cordyceps militaris, Flammulina velutipes) might be a candidate for the treatment of skin inflammation.
Cytokine;HaCaT cell;Inflammation;Mushroom;TNF-;
 Cited by
국내 시판 식용버섯 열수 추출물의 피부미백 기능 연구,김현재;장병현;박건희;장갑열;박기문;

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