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The effect of the mushrooms extract on the PSA expression in prostate cancer cells
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  • Journal title : Journal of Mushroom
  • Volume 13, Issue 3,  2015, pp.181-184
  • Publisher : The Korean Society Of Mushroom Science
  • DOI : 10.14480/JM.2015.13.3.181
 Title & Authors
The effect of the mushrooms extract on the PSA expression in prostate cancer cells
Kim, Eun-Kyung; Tang, Yujiao; Choi, Heeri; Choi, Eun-Ju;
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 Abstract
Mushroom have long been valued as highly nutritious and tasty foods in many societies throughout the world. It is known for biological activities including anti-inflammatory and anti-oxidative potential. However little is known about anti-cancer property. In this study, we investigated the anti-prostate cancer activity of mushrooms. For that, eight kinds of mushrooms such as, T. matsutake, S. crispa, G. lucidum-US, G. lucidum-AS, C. cardinalis-BR, G. frondosa, P. linteus, U. esculenta were extracted with hot water. Among them, three kinds of mushrooms including T. matsutake, G. lucidum-US and C. militaris-BR extracts inhibited prostate specific antigen (PSA) expression in prostate cancer cell, LNCaP. These results demonstrate that some of mushrooms inhibited PSA expression suggesting that the mushrooms might be a candidate for the treatment of prostate cancer.
 Keywords
LNCaP;Mushroom;Prostate cancer;PSA;
 Language
Korean
 Cited by
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