Advanced SearchSearch Tips
Anti-diabetic efficacy of the alcoholic extracts in Ganoderma sp. and Phellinus Baumi
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
  • Journal title : Journal of Mushroom
  • Volume 13, Issue 4,  2015, pp.326-329
  • Publisher : The Korean Society Of Mushroom Science
  • DOI : 10.14480/JM.2015.13.4.326
 Title & Authors
Anti-diabetic efficacy of the alcoholic extracts in Ganoderma sp. and Phellinus Baumi
Cho, Jae-Han; Park, Hye-Sung; Han, Jae-Gu; Lee, Kang-Hyo; Jhune, Chang-Sung;
  PDF(new window)
This study was carried out to anti-diabetic efficacy of alcoholic extracts in Ganoderma species and Phellinus Baumi. Ganoderma species and Phellinus Baumi. showed inhibitory activity of PTP1B, which acts as negative regulator of diabetes. The is an important enzyme in the digestion of carbohydrates in the saliva and pancreatic. If inhibition of the enzyme Delaying the digestion rate of the carbohydrate can be reduced postprandial rise in blood glucose levels. The results of the tests the active level that showed a similar inhibition inhibitory activity and a positive control. Phellinus Baumi. showed the inhibitory activity to 89%, Acarbose as positive control. is an essential enzyme in the digestion and absorption of carbohydrates that break down carbohydrates into simple sugars polysaccharides. The results of the tests the active level that showed a low inhibitory activity. It is thought to be able to complement the shortcomings of conventional anti-diabetic drugs.
 Cited by
Anoja, S. A., Zhou, Y. P., Xie, J. T., Wu, J. A., Zhang, L.,Dey, L., Pugh, W., Rue, P. A., Polonsky, K. S. and Yuan,C. S. 2002. Antidiabetic effect of Panax ginseng berry extract and the identification of an effective component. Diabetes 51, 1851-1858. crossref(new window)

Braunwald, E., Fauci, A. S., Kasper, D. L., Hause, S. L.,Longo, D. L. and Jameson, J. L. 2011. Harison's Principles of Internal Medicine. 15th ed, McGraw-Hill, New York, NY, USA. pp. 2109-2137.

Jeong, I.-K., Chung, J.-H., Min, Y.-K., Lee, M.-S., Lee, M.- K., Kim, K.-W., Joong, Y.-E., Park, J.-Y., Hong, S.-K. and Lee, K.-U. 2002. Comparative study about effects of acarbose and voglibose in type-2 diabetic patients. J Korean Diabetes 26, 134-145.

Lee, K. W., Shon, B. H., Kang, S. K., Park, D. H., Min, B. S. and Song, H. Y. 1984. Epidemiologic study for diabetes in 1821. Koreans. Diabetes 8, 5-14.

Matough, F. A., Budin, S. B., Hamid, Z. A., Alwahaibi, N. and Mohamed, J. 2012. The role of oxidative stress and antioxidant in diabetic complications. Squ Med J 12, 5-18.

Tsujimoto, T., Shioyama, E., Moriya, K., Kawaratani, H.,Shirai, Y., Toyohara, M., Mitoro, A., Yamao, J., Fujii, H. and Fukui, H. 2008. Pneumatosis cytosides intestinalis following alpha-glucosidase inhibitor treatment: a case report and review of the literature. World J Gastroenterol 14, 6087-6092. crossref(new window)

Xu, M.-L., Wang, L., Xu, G.-F. and Wang, M.-H. 2011. Antidiabetes and angiotensin converting enzyme inhibitory activity of Sonchus asper (L) Hill extract. Korean J Pharmacogn 42, 61-67.