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A Monte Carlo Study of Secondary Electron Production from Gold Nanoparticle in Kilovoltage and Megavoltage X-rays
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 Title & Authors
A Monte Carlo Study of Secondary Electron Production from Gold Nanoparticle in Kilovoltage and Megavoltage X-rays
Hwang, Chul-Hwan; Kang, Se-Sik; Kim, Jung-Hoon;
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 Abstract
This study investigated relationship between secondary electrons produced from single gold nanoparticle as a result of its interaction with radiation and particle size and incidence energy, provided basic data related to the dose enhancement effect based on gold nanoparticles. Monte Carlo simulation was applied by using MCNPX MC code, 50, 100, 150 kV and 6, 15 MV x-ray energy was used. In a water phantom, single gold nanoparticles that are 30, 50, 70, 90, and 110 nm in diameter were placed and the tally volume was designated at every 10 nm. Difference in electrons produced from gold nanoparticles was normalized based on absence of nanoparticle. When the X ray energy decreased and the diameter of gold particles increased, more electrons were produced. When the energy was lower, in the linear formula related to nanoparticle size and electron production, the gradient was higher. And, in comparison to the MV X-ray, at kV X-ray, significantly more electrons were produced. This study can be used as data to understand the dose enhancement effect based on gold nanoparticles, and further research related to various materials that dose enhancement including gold nanoparticles needs to be conducted.
 Keywords
Gold nanoparticle;Dose enhancement;Monte Carlo;
 Language
Korean
 Cited by
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