JOURNAL BROWSE
Search
Advanced SearchSearch Tips
The Apoptosis according to the Processing Irradiation and The Tumor Necrosis Factor
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
The Apoptosis according to the Processing Irradiation and The Tumor Necrosis Factor
Lee, Jaeseob; Jang, Seongjoo;
  PDF(new window)
 Abstract
Acute promyelocytic leukemia(APL) is not just the poor grades of treating a type of blood cancer hayeoteul combination with chemotherapy despite concurrent radiation therapy are known to exhibit a greater effect and also works on normal cells to result in side effects. In this study, when after treatment with gamma rays, such as in order to reduce these side effects was confirmed how affected the cell death of normal cells and cancer cells. HL-60 cells were used as the APL cell line HL-60 cells were differentiated with DMSO for treatment are shown the properties of normal granulocytes was used as a control group. As a result, HL-60 cells treated with and gamma rays with only showed a cytotoxic effect by inducing the apoptosis cells were put to death. Consequently, is thought to active substances that can increase the efficiency of cancer treatment to increase the removal of cancer cells when used with low-density gamma-ray treatment in order to eliminate the side effects of chemotherapy.
 Keywords
Acute promyelocytic leukemia;gamma ray;Tumor Necrosis Factor;Apoptosis;
 Language
English
 Cited by
 References
1.
Dongyeon Lee, Seongjin Ko, Sesik Kang, Changsoo Kim, Donghyun Kim, Junghoon Kim, "Dose Evaluation of Childhood Leukemia in Total Body Irradiation", Journal of Korean Society of Radiology, Vol. 7, No. 4, pp. 259-264, 2013. crossref(new window)

2.
Sung-Boo Hwang, Sehwan Han, Hyun-Suk Suh, Sung-Rok Kim, Hong-Yong Kim, "Preliminary Result of Concurrent Chemotherapy and Radiotherapy in Stage I and II Breast Cancer Patients Treated with Breast Conservation Surgery", The Korean Surgical Society, Vol. 59, No .4, pp. 458-462, 2016.

3.
Halperin EC, Constine LS, Tarbell NJ, "Pediatric radiation oncology. 5th ed", Philadelphia: Lippincott Williams & Wilkins 2011.

4.
Veronique Baud, Michael Karin, "Signal transduction by tumor necrosis factor and its relatives", Radiation therapy Oncology, Vol. 11, No. 9, pp. 372-377, 2001.

5.
Faustino Mollinedo, Ricardo Lopez-Perez, Consuelo Gajate,"Differential gene expression patterns coupled to commitment and acquisition of phenotypic hallmarks during neutrophil differentiation of human leukamia HL-60cells", Journal of Gene, Vol. 419, No. 1-2, pp. 16-26, 2008. crossref(new window)

6.
David Wallach, Mark Boldin, Eugene Varfolomeev, Rudi Beyaert, Peter Vandenabeele, Walter Fiers, "Cell death induction by receptors of the TNF family: to wards a molecular understanding", Journal of FEBS letters, Vol. 410, No. 1, pp. 96-106, 1997. crossref(new window)

7.
Karson S Putt, Grace W Chen, Jennifer M Pearson, Joseph S Sandhorst, Martin S Hoagland, Jung-Taek Kwon, Soon-Kyung Hwang, Hua Jin, Mona I Church well, Myung-Haing Cho, Daniel R Doerge, William G Helferich & Paul J Hergenrother, "Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy", Journal of Nature Chemical Biology, Vol. 2, pp. 543-550, 2006. crossref(new window)

8.
Dong Hyun Kim, Seong-Jin Ko, "Cell Death of Human Promyelocytic Leukemia Cell after Low Dose of Electron Beam Irradiation with TNF-${\alpha}$", Journal of the korea contents association, Vol. 14, No. 6, pp.241-246, 2014.

9.
Eun-Ju Yang, Dong-Hyun Kim, Jeong-Hyun Chang, "Extract of Listeria monocytogenes Induces the Apoptosis on the Human Promyelocytic Leukemia Cells, HL-60 Cells", Journal of the korea contents association, Vol. 12, No. 2, pp. 339-348, 2012. crossref(new window)

10.
M.Takeuchi,M.Rothe,andD.V.Goeddel,"Anatomy of TRAF2.Distinctdomains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteins" J Bio lChem, Vol. 6, p. 1993-1994, 1996.

11.
Young jae kim, Eun ju yang, "Tumor Necrosis Factor-${\alpha}$ with low dose radiation is induced the cell death of HL-60 cells", journal of korean society of radiology, pp. 93-96, 2015.