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Biochemical Changes in the Tissue of Mice Irradiated with LINAC
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 Title & Authors
Biochemical Changes in the Tissue of Mice Irradiated with LINAC
Choi, Seong-Kwan;
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 Abstract
In this study, a linear accelerator (LINAC) through 3 Gy of radiation per body irradiated mice of the small intestine and the liver to produce in order to protect the cells after radiation exposure that caspase (caspase 3 &caspase 9) and NO (nitric oxide), and looked like to know cytokine of IL-6 and TNF-, the result is as follows. First, caspase 3 & caspase 9 showed a noticeable increase in the radiation group than in the control group both small intestine and liver tissues (P <0.001). Second, NO are both intestine and liver tissue showed a marked increase in the radiation group than in the control group (P <0.001). Third, one of Cytokine IL-6 and TNF- showed a significant increase in the irradiated group than the control group both small intestine and liver tissues (P <0.001).
 Keywords
Caspase;NO;IL-6;TNF-;Cytokine;
 Language
Korean
 Cited by
 References
1.
김창수, 김동현, 김정훈, "후꾸시마 원전 사고 후 방사선 및 원전에 대한 인식 분석," 한국콘텐츠학회논문지, Vol.13, No.9, p.286, 2013.

2.
최종학, 임한영, 이준일, 강정호, 홍시영, 의료방사선생물학, 신광출판사, p.27, 2012.

3.
박주경, 이승훈, 차석용, 이선영, "간외 담도암 고선량률 관내근접방사선치료 시 몬테카를로 시뮬레이션을 통한 주변장기의 선량평가 연구," 한국콘텐츠학회논문지, Vol.14, No.2, p.467, 2014.

4.
박인국, 고인호, 김동윤, 박영순, 유병규, 방사선생물학, 청구문화사, pp.129-144, 2001.

5.
Shu-Zheng Liu, "Cellular and molecular changes induced by low-versus high-dose radiation," International Congress Series 1225, pp.179-188, 2002. crossref(new window)

6.
K. Myung-Sook, "Signaling and functional of caspase and c-Jun N-terminal kinase in cisplatin-induced apoptosis," Korean Society for Molecular and Cellular Biology, Vol.13, No.2, pp.194-201, 2002.

7.
G. Sethi and A. Sodhi, "In vitro activation of murine peritoneal macrophages by ultraviolet B radiation," Molecular immunology, Vol.40, pp.1315-1323, 2004. crossref(new window)

8.
M. Akmansu, D. Unsal, and H. Bora, "Influence of locoregional radiation treatment on tumor necrosis factor-$\alpha$ and interleukin-6 in the serum of patient with head and neck cancer," Cytokine, Vol.31, pp.41-45, 2005. crossref(new window)

9.
S. Kyrkanides, J. A. Olschowka, and J. P. Williams, "$TNF-{\alpha}$ and $IL-1{\beta}$ mediate intercellular adhesion molecule-1 induction via microglia-astrocyte interaction in CNS radiation injury," Journal of Neuroimmunology, Vol.95, pp.95-106, 1999. crossref(new window)