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Value of spray-dried plasma as a supplement to swine diets
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 Title & Authors
Value of spray-dried plasma as a supplement to swine diets
Jang, Kibeom; Kim, Junsu; Kim, Sheena; Jang, Yoontack; Lee, Jeongjae; Kim, Younghwa; Park, Juncheol; Kim, Younghoon; Song, Minho;
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One of the most powerful health management practices is the use of antibiotics, but their use is being restricted because of health safety issues. The swine industry has been looking for various alternatives to antibiotics and increasingly considers the use of dietary factors like feed ingredients, feed additives, feed formulation practices, or feeding methods, instead of using antibiotics to improve pig health and performance. Among other alternatives to antibiotics, spray-dried plasma may be a candidate. Spray-dried plasma is a blood product that provides bioavailable nutrients and physiologically active components such as immunoglobulins, glycoproteins, growth factors, peptides, etc. It is an excellent protein source with balanced and highly digestible amino acids. Several beneficial physiological activities depend on components of spray-dried plasma, such as immune competence (antibacterial activity), modulation of microbiota and/or immune system, integrity of intestinal barrier function, etc. These beneficial effects can contribute to improvement of pig performance and health by modulation of microbiota in the digestive tract and/or immune system. Therefore, it is suggested that spray-dried plasma has great potential as an antibiotics alternative.
growth;immunity;microbiota;spray-dried plasma;swine;
 Cited by
Bhandari SK, Xu B, Nyachoti CM, Giesting DW, Krause DO. 2008. Evaluation of alternatives to antibiotics using an Escherichia coli K88+ model of piglet diarrhea: Effects on gut microbial ecology. Journal of Animal Science 86:836-847. crossref(new window)

Bosi P, Casini L, Finamore A, Cremokolini C, Merialdi G, Trevisi P, Nobili F, Mengheri E. 2004. Spray-dried plasma improves growth performance and reduces inflammatory status of weaned pigs challenged with enterotoxigenic Escherichia coli K88. Journal of Animal Science 82:1764-1772. crossref(new window)

Carlson MS, Veum TL, Turk JR. 2005. Effects of yeast extract versus animal plasma in weanling pig diets on growth performance and intestinal morphology. Journal of Swine Health and Production 13:204-209.

Carroll JA, Touchette KJ, Matteri RL, Dyer CJ, Allee GL. 2002. Effect of spray-dried plasma and lipopolysaccharide exposure on weaned pigs: II. Effects on the hypothalamic-pituitary-adrenal axis of weaned pigs. Journal of Animal Science 80:502-509. crossref(new window)

Coffey RD, Cromwell GL. 1995. The impact of environment and antimicrobial agents on the growth response of early-weaned pigs to spray-dried porcine plasma. Journal of Animal Science 73:2535-2539.

Coffey RD, Cromwell GL. 2001. Use of spray-dried animal plasma in diets for weanling pigs. Pig News and Information 22:39N-48N.

Cromwell GL. 2002. Why and how antibiotics are used in swine production. Animal Biotechnology 13:7-27. crossref(new window)

Ermer PM, Miller PS, Lewis AJ. 1994. Diet preference and meal patterns of weanling pigs offered diets containing either spray-dried porcine plasma or dried skim milk. Journal of Animal Science 72:1548-1544. crossref(new window)

Frank JW, Carroll JA, Allee GL, Zannelli ME. 2003. The effects of thermal environment and spray-dried plasma on the acute-phase response of pigs challenged with lipopolysaccharide. Journal of Animal Science 81:1166-1176. crossref(new window)

Gaskins HR, Collier CT, Anderson DB. 2002. Antibiotics as growth promotants: Mode of action. Animal Biotechnology 13:29-42. crossref(new window)

Hardy B. 2002. The issue of antibiotic use in the livestock industry: What have we learned?. Animal Biotechnology 13:129-147. crossref(new window)

Jiang R, Chang X, Stoll B, Fan MZ, Arthington J, Weaver E, Compbell J, Burrin DG. 2000. Dietary plasma protein reduces small intestinal growth and lamina propria cell density in early weaned pigs. The Journal of Nutrition 130:21-26. crossref(new window)

Lambert GP. 2009. Stress-induced gastrointestinal barrier dysfunction and its inflammatory effects. Journal of Animal Science 87:E101-108. crossref(new window)

Markowska-Daniel I, Pejsak Z. 2006. Immunological and production parameters in pigs fed spray-dried animal plasma. Bulletin of the Veterinary Institute in Pulawy 50:455-459.

Moreto M, Miro L, Polo J, Russell L, Campbell J, Weaver E, Crenshaw J, Perez-Bosque A. 2008. Oral porcine plasma proteins prevent the release of mucosal pro-inflammatory cytokines in rats challenged with S. aureus enterotoxin B. Gastroenterology 134:A524-A524.

Moreto M, Perez-Bosque A. 2009. Dietary plasma proteins, the intestinal immune system, and the barrier function of the intestinal mucosa. Journal of Animal Science 87:E92-E100. crossref(new window)

Niewold TA. 2007. The nonantibiotic anti-inflammatory effect of antimicrobial growth promoters, the real mode of action? A hypothesis. Poultry Science 86:605-609. crossref(new window)

Niewold, TA, van Dijk AJ, Geenen PL, Roodink H, Margry R, van der Meulen J. 2007. Dietary specific antibodies in spray-dried immune plasma prevent enterotoxigenic Escherichia coli F4 (ETEC) post weaning diarrhea in piglets. Veterinary Microbiology 124:362-369. crossref(new window)

Nofrarias M, Manzanilla EG, Pujols J, Gibert X, Majo N, Segales J, Gasa J. 2006. Spray-dried porcine plasma affects intestinal morphology and immune cell subsets of weaned pigs. Journal of Animal Science 84:2735-2742. crossref(new window)

Nollet H, Deprez P, Van Driessche E, Muylle E. 1999. Protection of just weaned pigs against infection with F18+ Escherichia coli by non-immune plasma powder. Veterinary Microbiology 65:37-45. crossref(new window)

NRC. 1998. Nutrient Requirements of Swine. (10th). National Academy Press, Washington, DC.

Owusu-Asiedu A, Nyachoti CM, Marquardt RR. 2003a. Response of early-weaned pigs to an enterotoxigenic Escherichia coli (K88) challenge when fed diets containing spray-dried porcine plasma or pea protein isolate plus egg yolk antibody, zinc oxide, fumaric acid, or antibiotic. Journal of Animal Science 81:1790-1798. crossref(new window)

Owusu-Asiedu A, Nyachoti CM, Baidoo SK, Marquardt RR, Yang X. 2003b. Response of early-weaned pigs to an enterotoxigenic Escherichia coli (K88) challenge when fed diets containing spray-dried porcine plasma or pea protein isolate plus egg yolk antibody. Journal of Animal Science 81:1781-1789. crossref(new window)

Perez-Bosque A, Pelegri C, Vicario M, Castell M, Russell L, Campbell JM, Quigley JD, Polo J, Amat C, Moreto M. 2004. Dietary plasma protein affects the immune response of weaned rats challenged with S. aureus superantigen B. The Journal of Nutrition 134:2667-2672. crossref(new window)

Perez-Bosque A, Amat C, Polo J, Campbell JM, Crenshaw J, Russell L, Moreto M. 2006. Spray-dried animal plasma prevents the effects of Staphylococcus aureus enterotoxin B on intestinal barrier function in weaned rats. The Journal of Nutrition 136:2838-2843. crossref(new window)

Pettigrew JE. 2006. Reduced use of antibiotic growth promoters in diets fed to weanling pigs: Dietary tools, part 1. Animal Biotechnology 17:207-215. crossref(new window)

Pettigrew JE, Gaskins HR, Nava G. 2006. Research Report, National Pork Board. NPB #04-142 in Animal Science. A critical review of functional animal proteins. Accessed in on December, 2015.

Pluske JR, Pethick DW, Hopwood DE, Hampson DJ. 2002. Nutritional influences on some major enteric bacterial diseases of pigs. Nutrition Research Reviews 15:333-371.

Stein HH, Kil DY. 2006. Reduced use of antibiotic growth promoters in diets fed to weanling pigs: Dietary tools, part 2. Animal Biotechnology 17:217-231. crossref(new window)

Touchette KJ, Carroll JA, Allee GL, Matteri RL, Dyer CJ, Beausang LA, Zannelli ME. 2002. Effect of spray-dried plasma and lipopolysaccharide exposure on weaned pigs: I. Effects on the immune axis of weaned pigs. Journal of Animal Science 80:494-501. crossref(new window)

van Dijk AJ, Enthoven PM, van den Hoven SG, van Laarhoven MM, Niewold TA, Nabuurs MJ, Beynen AC. 2002. The effect of dietary spray-dried porcine plasma on clinical response in weaned piglets challenged with a pathogenic Escherichia coli. Veterinary Microbiology 84:207-218. crossref(new window)

van Dijk AJ, Everts H, Nabuurs MJ, Margry RJCF, Beynen AC. 2001. Growth performance of weanling pigs fed spray-dried animal plasma: A review. Livestock Production Science 68:263-274. crossref(new window)

Zhao J, Harper AF, Jr. Webb KE, Kuehn LA, Gilbert E, Xiao X, Wong EA. 2008. Cytokine mRNA expression in the small intestine of weanling pigs fed diets supplemented with specialized protein or peptide sources. Asian-Australasian Journal of Animal Sciences 21:1800-1806. crossref(new window)