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Application of Optimized Gompertz Algorithm for Estimation of Controlled Drug Release
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 Title & Authors
Application of Optimized Gompertz Algorithm for Estimation of Controlled Drug Release
Choe, Se-Woon; Woo, Young Woon;
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 Abstract
A Gompertz modeling, sigmoid in shape, is a widely used application for social science, natural science, engineering, and medical research to allow confident approximation and accurate analysis and has been applied to estimate an elderly population on aging of population. Due to the high toxicity of currently available drug delivery vehicles, various efforts have been made to reduce side-effects in clinical fields, but its application to preclinical and clinical studies is limited and there are some difficulties to optimize the parameters of Gompertz modeling applicable to preclinical studies. Therefore, in this study, we demonstrated the ability of sickle red blood cells loaded by hypotonic dialysis then photosensitized and light-activated ex vivo for controlled release and simultaneously optimized Gompertz function to evaluate controlled drug release properties of photosensitized sickle red blood cells to reduce pain-related treatments in cancer patients.
 Keywords
Gompertz modeling;Cancer;Sickle red blood cells;Photosensitizer;
 Language
Korean
 Cited by
1.
전임상 혈관분석을 위한 초분광 이미징 시스템의 활용,최세운;우영운;

한국컴퓨터정보학회논문지, 2015. vol.20. 4, pp.69-76 crossref(new window)
 References
1.
B. Haley, E. Frenkel. "Nanoparticles for drug delivery in cancer treatment," Urologic Oncology, Vol. 26, pp. 57-64, January-February 2008. crossref(new window)

2.
V. P. Torchilin, "Recent advances with liposomes as pharmaceutical carriers," Nature Reviews Drug Discovery, Vol. 4, pp. 145-160, February 2005. crossref(new window)

3.
L. H. Reddy, "Drug delivery to tumours: recent strategies," Journal of Pharmacy and Pharmacology, Vol. 57, Issue 10, pp. 1231-1242, February 2010.

4.
R. I. Pakunlu, Y. Wang, M. Saad, J. J. Khandare, V. Starovoytov, T. Minko, "In vitro and in vivo intracellular liposomal delivery of antisense oligonucleotides and anticancer drug," Journal of Controlled Release, Vol. 114, Issue 2, pp. 153-162, August 2006. crossref(new window)

5.
Y. Godfrin, F. Horand, R. Franco, E. Dufour, E. Kosenko, B. Bax, A Banz, O. Skorokhod, J. Lanao, V. Vitvitsky, E. Sinauridze, V. Bourgeaux, K. C. Gunter, "International Seminar on the Red Blood Cells as Vehicles for Drugs" Expert Opnion on Biological Therapy, Vol. 12, No. 1, pp. 127-133, January 2012. crossref(new window)

6.
E. Ruoslahti, "Vascular zip codes in angiogenesis and metastasis," Biochemical Society Transactions, Vol. 32, pp. 397-402, June 2004. crossref(new window)

7.
M. Milosevic, I. Quirt, W. Levin, A. Fyles, L. Manchul, W. Chapman. "Intratumoral sickling in a patient with cervix cancer and sickle trait: effect on blood flow and oxygenation," Gynecologic Oncology, Vol. 83, Issue 2, pp. 428-431, November 2001. crossref(new window)

8.
M. A. Al-Akhras, L. I. Grossweiner, "Sensitization of photohemolysis by hypericin and Photofrin," Journal of Photochemistry and Photobiology B: Biology, Vol. 34, Issue 2-3, pp. 169-175, July 1996. crossref(new window)

9.
B. Gompertz, "On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies," Philosophical Transactions of the Royal Society of London, Vol. 115, pp. 513-583, January 1825. crossref(new window)

10.
D. Jukic, G. Kralik, R. Scitovski, "Least-squares fitting Gompertz curve," Journal of Computational and Applied Mathematics, Vol. 169, Issue 2, pp. 359-375, August 2004. crossref(new window)

11.
N. J. Moura Jr, M. B. Ribeiro, "Evidence for the Gompertz curve in the income distribution of Brazil 1978-2005," The European Physical Journal B, Vol. 67, Issue 1, pp. 101-120, January 2009. crossref(new window)

12.
J. Moreira, A. Deutsch, "Cellular automation models of tumor development: A critical review," Advances in Complex Systems, Vol. 5, Issue 2, pp. 247-267, June 2002. crossref(new window)

13.
V. S. Gopal, A. R. Kumar, A. N. Usha, A. Karthik, N. Udupa, "Effective drug targeting by Erythrocytes as Carrier Systems," Current Trends in Biotechnology and Pharmacy, Vol. 1, pp. 18-33, June 2007.

14.
S. Choe, D. S. Terman, A. E. Rivers, J. Rivera, R. Lottenberg, B. S. Sorg, "Drug-loaded sickle cells programmed ex vivo for delayed hemolysis target hypoxic tumor microvessels and augment tumor drug delivery," Journal of Controlled Release, Vol. 171, Issue 2, pp. 184-192, July 2013 crossref(new window)