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Effect of Hen Egg Supplementation on Blood Lipid Profile and Fecal Bile Acid of C57BL/6 Mouse Fed Normal and High Cholesterol Diet
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 Title & Authors
Effect of Hen Egg Supplementation on Blood Lipid Profile and Fecal Bile Acid of C57BL/6 Mouse Fed Normal and High Cholesterol Diet
Jang, Ae-Ra; Kim, Dong-Wook; Park, Jung-Eun; Choe, Ju-Hee; Kang, Geun-Ho; Ham, Jun-Sang; Oh, Mi-Hwa; Seol, Kuk-Hwan; Lee, Seung-Gyu; Kim, Dong-Hun; Kim, Hyoun-Wook; Hwang, Kyung-A; Hwang, Yu-Jin; Kim, Hye-Kyung;
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 Abstract
This study was conducted to evaluate the effect of whole egg supplementation on the blood lipid profiles and cholesterol levels of C57BL/6 mice. Sixty-six mice were divided into two groups: normal-diet supplemented and high-cholesterol diet supplemented. Lyophilized whole egg powder was mixed with the two diets at 2 and 10%: normal diet only, normal diet with 2 and 10% whole egg powder, high cholesterol diet only, high cholesterol diet with 2 and 10% whole egg powder. The mixed diets were fed for 5 wk and feeding condition (body weight change, feed intake, and feed efficiency ratio (FER)), blood lipid profiles (total cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein cholesterol, hepatic and fecal lipids (TG, TC)), and fecal bile acids were determined. No significant differences were found in body weight gain or FER after whole egg supplementation in both the normal and high-cholesterol diet fed groups. In the normal-diet fed mice, HDL-C increased significantly in the 2 and 10% whole-egg powder groups. In the high-cholesterol diet fed mice, administering 10% egg powder increased the atherogenic index compared to the control. Furthermore, administration of whole egg powder increased fecal bile acids dose dependently (p<0.05). These results indicate that administering 2% hen whole egg powder did not affect blood lipid profiles and was more beneficial for health by increasing HDL-C and aiding in the excretion of cholesterol by fecal bile acids than those in the control.
 Keywords
hen eggs;cholesterol;blood lipids;bile acid;
 Language
Korean
 Cited by
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Consumption of Water-Soluble Egg Yolk Extract on Growth Rate, Changes in Blood Cholesterol Levels, and Immune Modulation in BALB/c Mice,;;;;;;;;;;;;

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계란의 콜레스테롤은 심장질환과 무관 : 총설,강근호;김동훈;김혜경;장애라;조수현;성필남;박범영;

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난황 경구투여가 랫드의 콜레스테롤 대사에 미치는 영향,방한태;황보종;박상오;박병성;

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Lipid-lowering mechanism of egg yolk in normal rats, International Journal of Food Science & Technology, 2016  crossref(new windwow)
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Egg Cholesterol is not related with Heart Disease : A Review, Korean Journal of Poultry Science, 2013, 40, 4, 337  crossref(new windwow)
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Consumption of Water-Soluble Egg Yolk Extract on Growth Rate, Changes in Blood Cholesterol Levels, and Immune Modulation in BALB/c Mice, Korean Journal for Food Science of Animal Resources, 2013, 33, 5, 587  crossref(new windwow)
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