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Risk Assessment of Heavy Metals through Modified Milk Powder and Formulas
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 Title & Authors
Risk Assessment of Heavy Metals through Modified Milk Powder and Formulas
Choi, Hoon; Kim, Hyung-Soo; Park, Sun-Hee;
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The present study was carried out to assess dietary exposure and risk for the infant population by lead (Pb), cadmium (Cd), and arsenic (As) exposure through modified milk powder and formulas. Analysis of heavy metals was performed using a microwave device and inductively coupled plasma-mass spectrometry, the method for which was fully validated. Various samples (n
modified milk powder;formula;heavy metals;monitoring;risk assessment;
 Cited by
식품 중 무기비소의 위해 분석,양승현;박지수;조민자;최훈;

한국식품위생안전성학회지, 2016. vol.31. 4, pp.227-249 crossref(new window)
Risk Analysis of Inorganic Arsenic in Foods, Journal of Food Hygiene and Safety, 2016, 31, 4, 227  crossref(new windwow)
AOAC International (2002) AOAC guidelines for single laboratory validation of chemical methods for dietary supplements and botanicals. Association of Official Analytical Chemists International. Avaiable from:

Bae, H. J., Jun, M., and Kim, Y. G. (2007) Study on the vitamin contents of commercial powdered infant formula. J. Life Sci. 17, 1689-1694. crossref(new window)

Cataldo, D. A., Garland, T. R., and Wildung, R. E. (1981) Cadmium distribution and chemical fate in soybean plants. Plant Physiol. 68, 835-839. crossref(new window)

CODEX (2008) Codex general standard for contaminants and toxins in foods (CODEX STAN 193-1995). Codex Alimentarius Commission, Geneva, Switzerland, pp. 38-42.

Dabeka, R. W. (1989) Survey of lead, cadmium, cobalt and nikel in infant formulas and evaporated milks and estimation of dietary intakes of the elements by infants 0-12 months old. Sci. Total Environ. 89, 279-289. crossref(new window)

DeStefano, A. J., Zaidi, K., Cecil, T. L., Giancaspro, G. I., and the USP Elemental Impurities Advisory Panel (2010) Elemental impurities-information. Pharmacopeial Forum 36, 2-9.

EFSA (European Food Safety Authority) (2009) Scientific opinion of the panel on contaminants in the food chain on a request from the European Commission on cadmium in food. The EFSA J. 980, 1-139.

Finoli, C. and Rondinini, G. (1989) Evaluation of infant formula contamination in Italy. Food Chem. 32, 1-8. crossref(new window)

FSA (Food Standards Agency) (2006) Survey of metals in weaning foods and formulae for infants. Lundon, UK, pp. 5-27.

FSANZ (Food Standards Australia New Zealand) (2012) Australia New Zealand food standards code. Canberra BC, Australia, pp. 3-4.

GEMS/Food-Euro (1995) Report on workshop in the frame of GEMS/Food-EURO. Second workshop on reliable evaluation of low-level contamination of food, Kulmbach, Germany.

Houpert, P., Mehennaoui, S., Federspiel, B., and Milhaud, G. (1997) Cadmium and lead elimination through milk in the ewe. COLLOQUES-INRA, 317-324.

Ikem, A., Nwankwoalab, A., Odueyungboa, S., Nyavora, K., and Egiebora, N. (2002) Levels of 26 elements in infant formula from USA, UK, and Nigeria by microwave digestion and ICP-OES. Food Chem. 77, 439-447. crossref(new window)

JECFA (Joint FAO/WHO Expert Committee on Food Additives) (2010) Summary and conclusions of seventy-third meeting (JECFA/73/SC). Geneva, Switzerland, pp. 12.

Jin, H. S. (2005) Development of Korean dairy industry - infant formula. J. Korean Dairy Technol. Sci. 23, 155-160.

Kazi, T. G., Jalbani, N., Baig, J. A., Afridi, H. I., Kandhro, G. A., Arain, M. B., Jamali, M. K., and Shah A. Q. (2009) Determination of toxic elements in infant formulae by using electrothermal atomic absorption spectrometer. Food Chem. Toxicol. 47, 1425-1429. crossref(new window)

KCDC (Korea Centers for Disease Control and Prevention), The Korean Pediatrics Society, and Committee for establishment of physical growth standard for Infant and adolescent (2007) Diagram of standard growth for infant and adolescent.

Kim, M. J., Park, E. K., Jun, M., and Kim, Y. G. (2007) Study on the mineral contents of commerical powdered infant formula. J. Life Sci. 17, 836-840. crossref(new window)

Kim, K. S. (2008) Studies on the analysis of heavy metals and foreign substances of infant formula. Annual report of National Veterinary Research and Quarantine Sevice, Anyang, Korea, pp. 40-49.

MFDS (Ministry of Food and Drug Safety) (2013a) Food code. Cheongwon, Korea.

MFDS (Ministry of Food and Drug Safety) (2013b) Livestock products sanitary control act (presidential decree 11690, revised 2013.03.23, a data of enforcement 2013.03.23). Cheongwon, Korea.

Milacic, R. and Kralj, B. (2003) Determination of Zn, Cu, Cd, Pb, Ni and Cr in some Slovenian foodstuffs. European Food Res. Technol. 217, 211-214. crossref(new window)

MOH (Ministry of Health) (2012) National food safety standard - maximum levels of contaminants in food (GB2762-2012).

Murthy, G. K. and Rhea, U. S. (1971) Cadmium, copper, iron, lead, manganese, and zinc in evaporated milk, infant products, and human milk. J. Dairy Sci. 54, 1001-1005. crossref(new window)

Neathery, M. W. and Miller, W. J. (1975) Metabolism and toxicity of cadmium, mercury, and lead in animals: A review. J. Dairy Sci. 58, 1767-1781. crossref(new window)

Park, K. S., Kim, S. T., Kim, Y. M., Kim, Y., and Lee, W. (2002) The matrix effect of biological concomitant element on the signal intensity of Ge, As, and Se in inductively coupled plasma/mass spectrometry. Bull. Korean Chem. Soc. 23, 1389-1393. crossref(new window)

Stephen, G. C., William, R. M., and William, C. C. (2008) FDA elemental analysis manual: section 4.0.2 method performance checks. U.S. Food and Drug Administration, Washington DC, USA. Available from: Accessed Sep. 10, 2012.

EC (The commission of the European communities) (2006) Commission Regulation(EC) No 1881/2006 of 19 December 2006 setting maximum levels for certain contaminants in foodstuffs. Official J. Eur. Union L364, 5-24.

US FDA (US Food and Drug Administration) (2010) Total diet study. Washington DC, USA. Available from: Accessed Oct. 1, 2012.

Vela, N. P. and Hettkemper, D. T. (2004) Total arsenic determination and speciation in infant food products by ion chromatography-inductively coupled plasma-mass spectrometry. J. AOAC Int. 87, 244-252.

WHO (World Health Organization) (1967) Specifications for the identify and purity of food additives and their toxicological evaluation (Tenth report of the Joint FAO/WHO Expert Committee on Food Additives). WHO Technical Report Series, No. 373, Geneva, Switzerland, pp. 15.

WHO (World Health Organization) (2000) Evaluation of certain food additives and contaminants (Fifty-third report of the Joint FAO/WHO Expert Committee on Food Additives). WHO Technical Report Series, No. 896, Geneva, Switzerland, pp. 81-82.

WHO (World Health Organizaiton) (2005) Dietary exposure assessment of chemicals in food. Geneva, Switzerland, pp. 1-2.