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Physiological Characteristics and Anti-obesity Effect of Lactobacillus plantarum Q180 Isolated from Feces
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 Title & Authors
Physiological Characteristics and Anti-obesity Effect of Lactobacillus plantarum Q180 Isolated from Feces
Park, Sun-Young; Cho, Seong-A; Kim, Sae-Hun; Lim, Sang-Dong;
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Obesity is strongly associated with several metabolic and chronic diseases and has become a major public health problem of worldwide concern. This study aimed to investigate the physiological characteristics and anti-obesity effects of Lactobacillus plantarum Q180. Lactobacillus plantarum Q180 was isolated from the faces of healthy adults and found to have a lipase inhibitory activity of and inhibited adipocyte differentiation of 3T3-L1 cells () at a concentration of . The strain was investigated for its physiological characteristics. The optimum growth temperature of L. plantarum Q180 was . Lactobacillus plantarum Q180 showed higher sensitivity to novobiocin in a comparison of fifteen different antibiotics and showed the highest resistance to rifampicin, polymyxin B and vancomycin. The strain showed higher -galactosidase and N-acetyl--glucosaminidase activities. It also did not produce carcinogenic enzymes such as -glucuronidase. The survival rate of L. plantarum Q180 in MRS broth containing 0.3% bile was 97.8%. Moreover, the strain showed a 97.2% survival rate after incubation for 3 h in pH 2.0. Lactobacillus plantarum Q180 was displayed resistance to Escherichia coli, Salmonella Typhimurium and Staphylococcus aureus with rates of 55.6%, 38.0% and 47.6%, respectively. These results demonstrate that L. plantarum Q180 has potential as a probiotic with anti-obesity effects.
Lactobacillus plantarum;physiological characteristics;anti-lipase activity;anti-adipogenic activity;
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