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Biological Activity Review of Mume Fructus and Processed Mume Fructus
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  • Journal title : The Korea Journal of Herbology
  • Volume 31, Issue 3,  2016, pp.59-69
  • Publisher : The Korea Association of Herbology
  • DOI : 10.6116/kjh.2016.31.3.59.
 Title & Authors
Biological Activity Review of Mume Fructus and Processed Mume Fructus
Ku, Garam; Kwon, OJun; Roh, Seong-Soo; Seo, Young-Bae;
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Objectives: Presently Mume Fructus (MF) undergoes fumigation, which produces benzo[a]pyrene. As a primary analysis with the aims to minimize the production of benzo[a]pyrene and to suggest standards for processing the MF, the steaming method was chosen among the various processing methods, and reviewed through a series of experiments.Methods: Methods:Pitted and un-pitted MF were steamed and processed into samples. After testing level of benzo[a]pyrene, the samples were analyzed for amount of polyphenol and flavonoids. Scavenging activities of the samples for the DPPH and ABTS radicals were tested. In order to measure anti-inflammatory effects of the samples, cell survival rate was investigated using CCK-8 Assay. Also, water extracts of dried and steamed MF were administered to the RAW 264.7 cells to compare expressions of NO, PGE2, IL-1β, and TNF-α. In addition, anti-diarrhea effects of the herbal medicine were tested on animal models with diarrhea induced by MgSO4 and Castor oil.Results: Regardless of pitting, processed MF contained no benzo[a]pyrene. Anti-oxidation effect increased in relation to the frequency of steaming process. However, extracts of dried and steamed MF suppressed different kinds of inflammation factors, and extract of dried MF showed superior anti-diarrhea effect than extract of steamed MF.Conclusions: It is suggested that steaming method of MF is recommended for processing the herbal medicine without the production of benzo[a]pyrene. But regarding that dried and steamed MF showed differences in their anti-oxidative, anti-inflammatory, and anti-diarrhea effects, it is recommended to perform further researches on different efficacies of MF according to their processing methods.
Mume Fructus;benzo[a]pyrene;steaming process;anti-oxidation;anti-inflammation;anti-diarrhea;
 Cited by
The National College of Oriental Medicine, herbalism common materials Compilation Committee. Herbal medicine. Seoul : Yeonglim publisher. 2005 : 678-9.

Cha HS. Hwang JB. Park JS. Park YK. Jo JS. Changes in Chemical Composition of Mume Prunus mume Sieb. et Zucc Fruits during Maturation. Korean J. Postharvest SCI. Technol. 1999 ; 6(4) : 481-7.

Lee KD. Sikyungkangsul. Seoul : Sungkyunkwan university publishing department. 2011 : 72.

Yeo HK. A Study on Ways to Activate Tourism through Gwangyang Maesil. Food Science and industry. 2012 ; 45 : 10-19.

Min BI, Cu B. Effect of Ion beverage substitution to Maesil-beverage on the Exercise Performance. Korea Sport Reserch. 2003 ; 14 : 868-78.

Ha MH. Cho SH. Preservative effect of agricultural and marine products treated with Prunus mune extract. J. Agriculture & Life Science. 2005 ; 39(4) : 55-60.

Ko YH. Yang HY. Kang SY. Kim ES. Jang IS. Effects of a blend of Prunus mume extract as an alternative to antibiotics on growth performance, activity of digestive enzymes and microflora population in broiler chickens. Journal of Animal Science and Technology. 2007 ; 49(5) : 611-20. crossref(new window)

Lim SJ. Eun JB. Processing and Distribution of Maesil, Japanese Apricot in Korea. Food Science and industry. 2012. ; 45 : 2-9.

Kim NC. Present Condition of Maesil drink Industry. The Korean Society of Food Preservation. 2005 : 42-51.

Son SY. Son PI. Sinnongbonchokyung. Taipei : Oju publishing house. 1986 : 34.

Kim YD. Kang SK. Hyun KH. Contents of Cyanogenic Glucosides in Processed Foods and during Ripening of Ume According to Varieties and Picking Date. Korean Journal of Food Preservation. 2002 ; 9(1) : 42-5.

No CW. Chong BM. Kang SD. Seo KK. Effects of Fruit Thinning Time on Fruit Growth and Quality in Japanese Apricot. Korean journal of horticultural science & technology. 2004 ; 10 : 52.

Seo KS, Huh CK, Kim YD. Comparison of Antimicrobial and Antioxidant Activities of Prunus mume Fruit in Different Cultivars. Korean Journal of Food Preservation. 2008 ; 15(2) : 288-92.

Lee OK. Lee HJ. Shin YS. Ahn YG. Jo HJ. Shin HC. Kang HY. Quantitative Analysis of The Fruit Flesh of Prunus mume Siebold & Zuccarni. Korean J. Medicinal Crop Sci. 2007 ; 15(3) : 143-47.

Ha MH. Park WP. Lee SC. Choi SG. Cho SH. Antimicrobial Characteristic of Prunus mune extract. Korean J. Food Preserv. 2004 ; 13(2) : 198-203.

Hwang JY. Ham JW. Nam SH. The Antioxidant Activity of Maesil (Prunus mume). Korean J. Food SCI Technol. 2004 ; 36(3) : 461-64.

Bae YK. Choe TB. Antioxidant and Cell Activity Using Extracts of Mume Fructus. Korean Journal of Medicinal Crop Science. 2011 ; 19(5) : 388-94. crossref(new window)

Eun JB. Kim CA. Cha HS. Processing storage and packaging methods for a variety of applications of maesil. Korean Journal of Food Preservation. 2004 ; 3(1) : 68-80.

Min BI. Bae CW. Choi YS. Effect of Ion beverage substitution to Maesil-beverage on the Exercise Performance. Korea sport research. 2003 ; 14(2) : 868-78.

Jin HL. Lee BR. Lim KJ. Debnath T. Shin HM. Lim BO. Anti-Inflammatory effects of Prunus mume Mixture in Colitis Induced by Dextran Sodium Sulfate. Korean Journal of Medical Crop Science. 2011 ; 19(1) : 16-23. crossref(new window)

Ko BS. Park SK. Choi SB. Jun DW. Hypoglycemic Effects of Crude Extracts of Prunus mume. Journal of The Korean Society of Food Science and Nutrition. 2004 : 951-7.

『Republic of Korea Pharmacopeia』10th revision (KP X) : 1172-3

『Herbal Pharmacopoeia for other (herbal) Alimentarius (KHP)』.Ⅰ.General Provisions. Article No. 2013-235 : 3.

Baek WS The monitoring of benzo(a)pyrene`s content on the herbal medicines. Korea pharmaceutical test & research institute, 2009.

『Notice the Food and Drug Administration』 Article No. 2012-17.

Velioglu YS. Mazza G. Gao L & Oomah BD. Antioxidant activity and total phenolics in selected fruits, vegetables, and grain products. Journal of agricultural and food chemistry. 1998 ; 46(10) : 4113-7. crossref(new window)

Che SG. Standard Food Analysis. Paju : Jigu publisher. 2002 : 381-2.

Blosis MS. Antioxidant determinations by the use of a stable free radical. Nature, 1958 ; 26 : 1199-1200. crossref(new window)

Re R. Pellegrini N. Proteggente A. Pannala A. Yang M. Rice-Evans C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biol. Med. 1999 ; 26(9) : 1231-7. crossref(new window)

Kang MY. Jeong YH. Eun JB. Physical and Chemical Characteristics of Flesh and Pomace of Japanese Apricots (Prunus mume Sieb. et Zucc). Korean J. Food SCI Technol. 1999 ; 31(6) : 1434.

Kim HC. Herbal Pharmacology. Seoul : Jipmoon publisher. 2004 : 490-2.

Jung SE. Bae JH. The Effect of Prunus Mume Extracts on the Growth of HepG2 and HeLa Cell Lines. The Korean Nutrition Society. 2002 ; 35 : 439-45.

『Notice the Food and Drug Administration』 Article No. 2009-13.

Yoshizawa S. Horiuchi T. Yoshida T. Okuda T. Antitumor promoting activity of (-) epigallocatechin gallate. the main constitutent of tannin in green tea. Phytotherapy Research. 1987 ; 1(1) : 44-7. crossref(new window)

Kim JH. Yoo JS. Lee CH. Kim SoY. Lee SK. Quality properties of soybean pastes made from meju with mold production pretease. 2006 ; 49(1) : 7-14.

Kim SI. Sim KH. Ju SY. Han YS. A study of Antioxidantive and Hypoglycemic Activities of Omija(Schizandra chinensis Baillon) Extract under variable Extract Conditions. The Korean Journal of Food And Nutrition. 2009 ; 22(1) : 41-7.

Kaplanski G. Marin V. Nontero-Julian F. Mantovani A. IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation. Trends in immunology. 2003 ; 24(1) : 25-9. crossref(new window)

You GW. Jung L. Taepyungheyminhwajaegookbang. Beijing : People's health publisher. 2007 : 74.

Joe G. Sungjaechonglok. Seoul : Esdang publisher. 1993 : 684, 710, 832, 833, 2341, 2359.

Joo S. Bojaebang. Seoul : Esdang publisher. 1993 : 944, 974, 975.

Jung KH. Pojaehak. Daejeon : Munjin publisher. 2012 : 3-12.