PIV Measurement of Pulsatile Flows in 3D Curved Tubes Using Refractive Index Matching Method

Title & Authors
PIV Measurement of Pulsatile Flows in 3D Curved Tubes Using Refractive Index Matching Method
Hong, Hyeon Ji; Ji, Ho Seong; Kim, Kyung Chun;

Abstract
Three-dimensional models of stenosis blood vessels were prepared using a 3D printer. The models included a straight pipe with axisymmetric stenosis and a pipe that was bent $\small{10^{\circ}}$ from the center of stenosis. A refractive index matching method was utilized to measure accurate velocity fields inside the 3D tubes. Three different pulsatile flows were generated and controlled by changing the rotational speed frequency of the peristaltic pump. Unsteady velocity fields were measured by a time-resolved particle image velocimetry method. Periodic shedding of vortices occurred and moves depended on the maximum velocity region. The sizes and the positions of the vortices and symmetry are influenced by mean Reynolds number and tube geometry. In the case of the bent pipe, a recirculation zone observed at the post-stenosis could explain the possibility of blood clot formation and blood clot adhesion in view of hemodynamics.
Keywords
Pulsatile Flow;PIV Measurement;Refractive Index Matching;Vortex Motion;Stenosis Model;
Language
Korean
Cited by
References
1.
Davies, P. F., 2009, "Hemodynamic Shear Stress and the Endothelium in Cardiovascular Pathophysiology," Nature Reviews Cardiology, Vol. 6, pp. 16-26.

2.
Chiu, J-J., Chien, S., 2011, "Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives," Physiological Reviews, Vol. 91, pp. 327-387.

3.
Nerem, R. M., Levesque, M. J., Cornhill, J. F., 1981, "Vascular Endothelial Morphology as an Indicator of the Pattern of Blood Flow," Journal of Biomechanical Engineering, Vol. 103, No. 3, pp. 172-176.

4.
Karino, T., "Microscopic Structure of Disturbed Flows in the Arterial and Venous Systems, and its Implication in the Localization of Vascular Diseases," 1986, International Angiology: A Journal of the International Union of Angiology, Vol. 5, pp. 297-313.

5.
Fisher, A. B., Chien, S., Barakat, A. I. and Nerem, R. M., 2001, "Endothelial Cellular Response to Altered Shear Stress," American Journal of Physiology-Lung Cellular and Molecular Physiology, Vol. 281, No. 3, pp. L529-L533.

6.
Bluestein, D., Niu, L., Schoephoerster, R. T. and Dewanjee, M. K., 1997a, "Fluid Mechanics of Arterial Stenosis: Relationship to the Development of Mural Thrombus," Annals of Biomedical Engineering, Vol. 25, pp. 344-356.

7.
Bluestein, D., Niu, L., Schoephoerster, R. T. and Dewanjee, M. K., 1997b, "Fluid Mechanics of Arterial Stenosis: Relationship to the Development of MURAL Thrombus," Annals of Biomedical Engineering, Vol. 25, pp. 344-356.

8.
PDAY Research Group, 1993, "Natural History of Aortic and Coronary Atherosclerotic Lesions in Youth. Findings from the PDAY Study," Arterioscler Thromb, Vol. 13 pp. 1291-1298.

9.
Wootton, D. M. and Ku, D. N., 1999a, "Fluid Mechanics of Vascular Systems, Diseases, and Thrombosis," Annual Review of Biomedical Engineering, Vol. 1, pp. 299-329.

10.
Cheng, N. S., 2008, "Formula for the Viscosity of a Glycerol-Water Mixture," Industrial and Engineering Chemistry Research, Vol. 47, pp. 3285-3288.