Journal of The Korean Ophthalmological Society (대한안과학회지)

The Korean Ophthalmological Society (대한안과학회)
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Therapeutic Effect of Topical Autologous Serum in Recurrent Punctate Corneal Erosion

반복성 점상 각막미란에서 자가혈청 국소점안의 치료효과

Han, Myeong-Soo;Lee, Jong-Hyuck;Lee, Seok-Joon
한명수;이종혁;이석준

  • Published : 20041000
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Abstract

Purpose: To study the effect of topical autologous serum in the treatment of recurrent punctate corneal erosions. Methods: A total of 10 eyes from recurrent corneal erosion patients, who had suffered from recurrence after initial treatment with conventional therapy were treated using topical autologous serum from October 2001 to April 2003. We investigated the efficacy of this method over conventional therapy by retrospective review of their medical records. Results: The recurrence rate of erosions before treatment with autologous serum eyedrops ranged from once every 2months to twice a month. Mean follow-up time was 11.0${\pm}$4.6 months (range, 6${\sim}$19 months). There was one case of recurrence 3 months after first treatment with autologous serum eyedrops which was effectively cured with autologous serum eyedrops. No side effects were noted in any of the treated patients. Conclusions: Topical autologous serum application may be considered as an effective and safe treatment modality in recurrent corneal erosions.

목적: 반복성 점상 각막미란에서 자가혈청 국소점안의 치료 효과에 대해서 알아보고자 하였다. 대상과 방법 : 2001년 10월부터 2003년 4월 사이에 반복성 점상 각막미란으로 진단받고 기존의 고식적인 치료에도 불구하고 재발하여 자가혈청 국소점안으로 치료한 환자 총 10명 10안을 대상으로 의무기록을 이용하여 후향적 연구조사를 실시하였다. 결과 : 자가혈청 국소점안으로 치료 전 각막미란의 재발 빈도는 평균 2달 1회에서 1달 2회 정도였고, 치료 후 평균 관찰기간 11.0${\pm}$4.6개월(6${\sim}$19개월)동안 재발은 1안에서 1차 치료 후 3개월 후에 발생하였으나, 자가혈청의 국소점안으로 다시 효과적으로 치료되었다. 치료받은 어떠한 환자에서도 합병증은 발생하지 않았다. 결론 : 자가혈장의 국소점안은 반복성 점상 각막미란에서 효과적이고 안전한 치료방법으로 고려될 수 있겠다.

Keywords

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