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Advancing Risk Assessment through the Application of Systems Toxicology
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  • Journal title : Toxicological Research
  • Volume 32, Issue 1,  2016, pp.5-8
  • Publisher : The Korean Society of Toxicology
  • DOI : 10.5487/TR.2016.32.1.005
 Title & Authors
Advancing Risk Assessment through the Application of Systems Toxicology
Sauer, John Michael; Kleensang, Andre; Peitsch, Manuel C.; Hayes, A. Wallace;
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 Abstract
Risk assessment is the process of quantifying the probability of a harmful effect to individuals or populations from human activities. Mechanistic approaches to risk assessment have been generally referred to as systems toxicology. Systems toxicology makes use of advanced analytical and computational tools to integrate classical toxicology and quantitative analysis of large networks of molecular and functional changes occurring across multiple levels of biological organization. Three presentations including two case studies involving both in vitro and in vivo approaches described the current state of systems toxicology and the potential for its future application in chemical risk assessment.
 Keywords
Systems toxicology;Risk assessment;
 Language
English
 Cited by
1.
Shedding New Lights with the Breakthrough Ideas to Understand Current Trends in Modern Toxicology, Toxicological Research, 2016, 32, 1, 1  crossref(new windwow)
 References
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