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Overview on Peroxiredoxin
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  • Journal title : Molecules and Cells
  • Volume 39, Issue 1,  2016, pp.1-5
  • Publisher : Korea Society for Molecular and Cellular Biology
  • DOI : 10.14348/molcells.2016.2368
 Title & Authors
Overview on Peroxiredoxin
Rhee, Sue Goo;
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Peroxiredoxins (Prxs) are a very large and highly conserved family of peroxidases that reduce peroxides, with a conserved cysteine residue, designated the "peroxidatic" Cys () serving as the site of oxidation by peroxides (Hall et al., 2011; Rhee et al., 2012). Peroxides oxidize the -SH to cysteine sulfenic acid (-SOH), which then reacts with another cysteine residue, named the "resolving" Cys () to form a disulfide that is subsequently reduced by an appropriate electron donor to complete a catalytic cycle. This overview summarizes the status of studies on Prxs and relates the following 10 minireviews.
circadian rhythm;hydrogen peroxide;peroxiredoxin;redox regulation;thiol-specific peroxidasee;
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The Role of Peroxiredoxins in the Transduction of H2O2 Signals, Antioxidants & Redox Signaling, 2017  crossref(new windwow)
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