Advanced SearchSearch Tips
Detection of 881A→881G Mutation in Tyrosinase Gene and Associations with the Black Ear Coat Color in Rabbits
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Detection of 881A→881G Mutation in Tyrosinase Gene and Associations with the Black Ear Coat Color in Rabbits
Jiang, Y.L.; Fan, X.Z.; Lu, Z.X.; Tang, H.; Xu, J.-Q.; Du, L.-X.;
  PDF(new window)
The tyrosinase gene was selected as a candidate for uncovering genetic mechanism causing 'black ear' coat color in rabbits. A PCR-SSCP detection method was established for the mutation located in the central region of the tyrosinase gene between the CuA and CuB binding region signatures, and this was confirmed by sequencing and alignment. Fully consistent associations between the SNP and 'black ear' coat color were observed by analysis in a "black ear" pedigree and on 61 unrelated individuals. This SNP can serve as a molecular marker for use in "back ear" wool rabbit breeding.
Rabbit;Black Ear Coat Color;Tyrosinase Gene;PCR-SSCP;SNP Marker;
 Cited by
Associations of Single Nucleotide Polymorphisms in BMPR-IB Gene with Egg Production in a Synthetic Broiler Line,Zhang, N.B.;Tang, H.;Kang, L.;Ma, Y.H.;Cao, D.G.;Lu, Y.;Hou, M.;Jiang, Y.L.;

Asian-Australasian Journal of Animal Sciences, 2008. vol.21. 5, pp.628-632 crossref(new window)
Aigner, B., U. Besenfelder, M. Müller and G. Brem. 2000. Tyrosinase gene variants in different rabbit strains. Mamm Genome 11:700-702. crossref(new window)

Jackson, I. J. 1994. Molecular and developmental genetics of mouse coat color. Annu Rev Genet 28:189-217. crossref(new window)

Jiang, Y-L., L-X. Du, L. Zhang, Y- F. Zhang, C- G. Jiang and LR. Xiao. 1997. Detection of the Haln gene in pigs of imported breeds in Shandong province. Proceedings in Animal Breeding and Genetics in China, 1997. pp. 94-97.

Jiang, Y-L., N. Li, Q-Y. Xi and C-X. Wu. 2000. Detection of porcine ESR gene point mutations by PCR-SSCP approach. Hereditas(Beijing) 22:214-216.

Oetting, W. S. and R. A. King. 1999. Moleclar basis of albinism: mutations and polymorphisms of pigmentation genes associated with albinism. Hum Mutat 13:99-115. crossref(new window)

Sambrook, J., E. F. Fritsch and T. Maniatis. 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.