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Association of Beta-lactoglobulin Polymorphism with Milk Production Traits in Cattle
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 Title & Authors
Association of Beta-lactoglobulin Polymorphism with Milk Production Traits in Cattle
Badola, S.; Bhattacharya, T.K.; Biswas, T.K.; Kumar, Pushpendra; Sharma, Arjava;
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The study was carried out in Sahiwal, Holstein Friesian, Jersey and crossbred cattle to find out the effect of genotype of beta-lactoglobulin gene on milk production traits. The polymorphism at beta-lactoglobulin gene was identified by conducting PCRRFLP studies. A 398 bp fragment of the gene was amplified and digested with Hae III restriction enzyme. The two alleles A and B and three genotypes AA, AB and BB were identified in all cattle breeds. The frequency of B allele was comparatively higher than that of A allele. The AA genotype produced significantly higher milk yield in Sahiwal cattle whereas BB genotype yielded higher milk in Holstein friesian cattle. In other cattle breeds the genotypic effect was non-significant. In conclusion it may be stated that the genotype with significantly higher milk yield may be favoured in the farm along with other conventional selection criteria to enhance the milk production of animals.
Association;Beta-lactoglobulin Gene;Milk Production Trait;Polymorphism;
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Aleandri, R. G., R. G. Buttazzoni, J. C. Schneider, A. Caroli and R. Davoli. 1990. The effects of milk protein polumorphism on milk components and cheese producing ability. J. Dairy Sci. 73:241.

Alexander, L. J., G. Hayes, W. Bawden, A. F. Stewart and A. G. Mackinalay. 1989. Complete nucleotide sequence of the bovine beta-lactoglobulin gene. Anim. Biotechnol. 4:1.

Aschaffenburg, R. and J. Drewry. 1955. Occurrence of different beta-lactoglobulin in cow’s milk. Nature 176:218-219.

Bhattacaharya, T. K. and R. S. Gandhi. 1997. Marker assisted selection (MAS) and its application in dairy cattle. Indian Dairyman 49:39-45.

Biswas, T. K., T. K. Bhattacharya, A. D. Narayan, S. Badola, P. Kumar and A. Sharma. 2003. Growth hormone gene polymorphism and its effect on birth weight in cattle and buffalo. Asian-Aust. J. Anim. Sci. 16:494-497.

Eigel, W. N., J. E. Butler, C. A. Emstorm, H. M. Farrel, R. J. Harwalkar and R. M. Whitney. 1984. Nomenclature of proteins of cow’s milk: Fifth revision. J. Dairy Sci. 67:1599.

Falconer, D. S. 1998. Introduction to Quantitative genetics. Rd 4th, Addison wesley Longman Ltd. Essex, England.

Jairam, B. T. and P. G. Nair. 1983. Genetic polymorphism of milk proteins and economic characters in dairy animals. Indian J. Anim. Sci. 53:1.

Kim, J. H., H. D. Shin, S. W. Han, B. C. Sang and Y. S. Won. 1997. Polymorphism of kappa-casein and beta-lactoglobulin genes using the polymerase chain reaction in Hanwoo (Korean native) cattle. Korean J. Anim. Sci. 39:481-488.

Kudjal-Savoie, S., W. Manson and J. H. Moore. 1980. The constutuents of cow’s milk. Bull. Int. Dairy Fed. 125:4-13.

Ng-Kwai-hang, K. F., J. F. Hayes, J. E. Moxley and H. G. Monardes. 1990. Relationship between milk protein polymorphism and major milk constituents in Holstein Friesian cows. J. Dairy Sci. 69:22.

Sambrook, J., E. F. Fritsch and T. Maniatis. 1989. Molecular Cloning: A laboratory Manual. Ed 2nd, Vol 2. Cold Spring Harbour Laboratory Press, New York

Singh, H., P. N. Bhatt and R. Singh. 1981. Association of milk protein polymorphic genotypes with certain performance traits in crossbred cattle. Indian J. Anim. Sci. 51:5-10.

Snedecor, G. W. and W. G. Cochran. 1967. Statistical methods. Ed. 6th, Oxford and IBM Publishing Co., New Delhi.

Zhou, J. F., D. Zadworny and U. Kuhnlein. 1996. Sequence analysis of the beta-lactoglobulin locus in Holstein identifies two new restriction fragment length polymorphism. Canadian J. Anim. Sci. 76:299-303.