Advanced SearchSearch Tips
Effects of Dietary Chromium Picolinate Supplementation on Growth Performance and Immune Responses of Broilers
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Effects of Dietary Chromium Picolinate Supplementation on Growth Performance and Immune Responses of Broilers
Lee, Der-Nan; Wu, Fu-Yu; Cheng, Yeong-Hsiang; Lin, Rong-Shinn; Wu, Po-Ching;
  PDF(new window)
Two experiments were conducted to evaluate the effects of chromium (Cr) on the growth performance, bone trait, serum traits, and immune responses in broilers. The broilers were fed corn-soybean meal basal diet supplemented with Cr at level of 0(control), 200, 400, or 800 ppb in the form of chromium picolinate (CrPic). The broilers were fed treated diets for 6 weeks in Exp. 1, but the Cr supplement was removed for the last 3 weeks in Exp. 2. Exp. 1 showed that dietary supplement of Cr did not affect growth performance of the broiler, though improved feed efficiency (p<0.05) was observed during 0 to 3 weeks. Moreover, serum total (p<0.05) and HDL cholesterols (p<0.06) were significantly higher in pooled Cr added group at 6 weeks of age, however, the difference was not significant in Exp. 2. The pooled Cr added group in Exp.1 had significantly lower (p<0.05) alkaline phosphatase activity and higher (p<0.09) calcium at 3 weeks. Significantly lower phosphorus was also observed in Exp. 2. With continued supplement of Cr as in Exp. 1, the alkaline phosphatase activity maintained higher at 6 weeks, as opposed to significantly lower in Exp. 2, which had no further Cr supplement. Higher bone breaking strength was observed in 400 ppb Cr supplemented in Exp. 1, though not significantly different. Serum glucose and triglyceride were not affected by Cr supplement. Antibody against Infectious Bronchitis (IB) was significantly (p<0.05) higher with 400 ppb Cr supplemented, and anti-Newcastle disease (ND) antibody also tended to be higher (p<0.06) in pooled Cr added group at 6 weeks of age in Exp. 1. Peripheral blood blastogenesis activity was not different among the treatments. The results suggest that diet supplemented with 400 ppb CrPic may be beneficial to the broiler.
Chromium Picolinate;Broiler;Growth Performance;Immune Response;
 Cited by
Immune Response of Broiler Chickens Fed Diets Supplemented with Different Level of Chromium Methionine under Heat Stress Conditions,;;;

아세아태평양축산학회지, 2012. vol.25. 2, pp.256-260 crossref(new window)
Amoikon, E. K., J. M. Fernander, L. L. Southern, D. L. Thompson, Jr., T. L. Ward and B. M. Olcott. 1995. Effect of chromium tripicolinate on growth, glucose tolerance, insulin sensitivity, plasma metabolites and growth hormone in pigs. J. Anim. Sci. 73:1123-1130.

Anderson, R. A. and A. S. Kozlovsky. 1985. Chromium intake, absorption and excretion of subjects consuming self-selected diets. Am. J. Clin. Nutr. 41:1177-1183.

Anderson, R. A., M. M. Polansky, N. A. Bryden and J. J. Canary. 1991. Supplemental-chromium effects on glucose, insulin, glucagon and urinary-chromium losses in subjects consuming controlled low-chromium diets. Am. Clin. Nutr. 54:909-916.

Bunting, L. D., J. M. Fernandez, D. L. Thompson, Jr. and L. L. Southern. 1994. Influence of chromium picolinate on glucose usage and metabolic criteria in growing Holstein calves. J. Anim. Sci. 72:1591-1599.

Burton, J. L., B. A. Mallard and D. N. Mowat. 1994. Effects of supplemental chromium on antibody responses of newly weaned feedlot calves to immunization with Infectious bovine rhinotracheitis and Parainfluenza 3 virus. Can. J. Vet. Res. 58:148-151.

Chang, X., B. A. Mallard and D. N. Mowat. 1996. Effects of chromium on health status, blood neutrophil phagocytosis and in vitro lymphocyte blastogenesis of dairy cows. Vet. Immuno. Immunopath. 52:37-52. crossref(new window)

Dowling, H. J., E. G. Offenbacher and F. X. Pi-Sunyer. 1989. Absorption of inorganic, trivalent chromium from the vascularly perfused rat small intestine. J. Nutr. 119:1138-1145.

Evans, G. W. and T. D. Bowman. 1992. Chromium picolinate increases membrane fluidity and rate of insulin internalization. J. Inorg. Biochem. 46:243-250. crossref(new window)

Fisher, J. A. 1990. The Chromium Program. Harper & Row, New York.

Gonzalez, R., J. Jimenez, H. Hernandez and J. L. Espinoza. 1997. Effect of chromium picolinate on performance and carcass components of broiler chickens. J. Anim. Sci. 75(Suppl. 1):113(Abstr.).

Guo, Y. L., X. G. Luo, Z. L. Hao, B. Liu, J. L. Chen, F. S. Gao and S. X. Yu. 1999. Effect of chromium on growth performance, serum biochemical traits immune functions and carcass quality of broiler chickens. Scientia Agri. Sinica 32:79-86.

Hermann, J., C. Goad, B. Stoecker, A. Arquitt, R. Porter, B. Adeleye, P. L. Claypool and G. Brusewitz. 1997. Effects of dietary chromium, copper and zinc on femur fracture force and femur calcium calcium concentration in male Japanese quail. Nutr. Res. 17:1529-1540. crossref(new window)

Hossain, S. M., S. L. Barreto and C. G. Silva. 1998. Growth performance and carcass composition of broiler fed supplemental chromium from chromium yeast. Anim. Feed Sci. Technol. 71:217-228. crossref(new window)

Kaneko, J. J. 1980. Clinical Biochemistry of Domestic Animals. Academic Press, New York.

Kim, S. W., I. K. Han, Y. J. Choi, Y. H. Kim, I. S. Shin and B. J. Chae. 1995. Effects of chromium picolinate on growth performance, carcass composition and serum traits of broilers fed dietary different levels of crude protein. Asian-Aus. J. Anim. Sci. 5:463-470.

Kim, Y. H., I. K. Han, Y. J. Choi, I. S. Shin, B. J. Chae and T. H. Kang. 1996a. Effects of dietary levels of chromium picolinate on growth performance, carcass quality and serum traits in broiler chicks. Asian-Aus. J. Anim. Sci. 9:340-347.

Kim, Y. H., I. K. Han, I. S. Shin, B. J. Chae and T. H. Kang. 1996b. Effect of dietary excessive chromium picolinate on growth performance, nutrient utilizability and serum traits in broiler chicks. Asian-Aus. J. Anim. Sci. 9:349-354.

Lee, D. N., H. T. Yen, T. F. Shen and B. J. Chen. 1997. The effects of chromium picolinate supplementation on growth performance and immunity response of weanling pigs. J. Chin. Soc. Anim. Sci. 26:373-386.

Lee, L. F. 1978. Chicken lymphocyte stimulation by mitogens: A microassay with whole-blood cultures. Avian Dis. 22:296-307. crossref(new window)

Lien, T. F., Y. M. Horng and K. H. Yang. 1999. Performance, serum characteristics, carcase traits and lipid metabolism of broilers as affected by supplement of chromium picolinate. Br. Poult. Sci. 40:357-363. crossref(new window)

Luo, X., Y. L. Guo, B. Liu, Z. L. He, J. L. Chen, F. S. Gao and S. X. Yu. 1999. Effect of dietary chromium on growth, serum biochemical traits and immune responses of broiler chicks during 0-3 weeks of age. Acta Vet. et Zootechnica Sinica 30:481-489.

McCarty, M. F. 1995. Anabolic effects of insulin on bone suggest a role for chromium picolinate in preservation of bone density. Med. Hypotheses 45:241-246. crossref(new window)

Min, J. K., W. Y. Kim, B. J. Chae, I. B. Chung, I. S. Shin, Y. J. Choi and In K. Han. 1997. Effects of chromium picolinate (CrP) on growth performance, carcass characteristics and serum traits in growing-finishing pigs. Asian-Aus. J. Anim. Sci. 10:8-14.

Motozono, Y. K. Hatano, N. Sugawara and T. Ishibashi. 1998. Effects of dietary chromium picolinate on growth, carcass quality and serum lipids of female broilers. Anim. Sci. Technol. (Jpn) 69:659-665.

National Research Council. 1994. Nutrient Requirements of Poultry. 9th Ed. National Academy Press, Washington, DC.

National Research Council. 1995. Nutrient Requirements of Laboratory Animals. 4th Ed. National Academy Press, Washington, DC.

Piao, X. S., I. K. Han, J. H. Kim, S. H. Bae, Y. H. Kim and C. Liang. 1997. Effects of metabolic active substances addition to diets with different protein level on the amount of excretion of N and P and performances of broiler. Korean J. Anim. Nutr. Feed. 21:407-418.

Rowland, L. O. Jr., R. H. Harms, H. R. Wilson, E. M. Ahmed, P. W. Waldroup and J. L. Fry. 1968. Influence of various dietary factors on bone fragility of caged layers. Poult. Sci. 47:507-511.

Sands, J. S. and M. O. Smith. 1999. Broilers in heat stress conditions: effects of dietary manganese proteinate or chromium picolinate supplementation. J. Appl. Poult. Res. 8:280-287.

SAS Institute Inc. 1999. SAS/STAT User's Guide: Release 6.12. SAS Institute Inc., Cary, North Carolina.

Schwarz, K. and W. Mertz. 1957. A glucose tolerance factor and its differentiation from factor 3. Arch. Biochem. Biophys. 72:515-518. crossref(new window)