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Relationships of Concentrations of Endocrine Factors at Antemortem and Postmortem Periods to Carcass Weight and Backfat Thickness in Pigs
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Relationships of Concentrations of Endocrine Factors at Antemortem and Postmortem Periods to Carcass Weight and Backfat Thickness in Pigs
Yun, J.S.; Seo, D.S.; Rhee, M.S.; Oh, S.; Kim, B.C.; Ko, Y.;
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Carcass weight and backfat thickness are two of important elements in determining the carcass trait in pigs and are studied on animal genetics, nutrition, and endocrinology. Growth factors stimulate or inhibit the proliferation and differentiation of various cells. In particular, insulin-like growth factors (IGFs), transforming growth factor (TGF)-, and epidermal growth factor (EGF) are involved in the growth and maintenance of muscle. Also, dehydroepiandrosterone-sulfate (DHEA-S) and cortisol are known to be related to the obesity and subcutaneous fat depth in pigs. Therefore, this study was performed to relate growth factors (IGFs, TGF-, and EGF) and hormones (cortisol and DHEA-S) concentrations at antemortem and postmortem periods to carcass traits including carcass weight and backfat thickness. Blood and m. Longissimus were collected in pigs at antemortem (30 days before slaughter) and postmortem periods. After slaughtered, carcass weight and backfat thickness were measured. Growth factors and hormones in serum and m. Longissimus were measured by radioimmunoassay or enzyme-linked imuunosorbent assay. Before antemortem period, serum IGF-I and -II concentrations were positively correlated with the carcass weight and backfat thickness in gilts, and the concentrations of TGF- and cortisol in barrows show the correlation with only carcass weight. Also, the positive correlations of muscular IGFs and TGF- at postmortem 45 min with the carcass weight and backfat thickness were detected. Consequently, these results suggest that the serum and muscular endocrine factors are involved in the carcass weight and backfat thickness in pigs.
Endocrine Factor;Growth Factor;Carcass Weight;Backfat Thickness;Pigs;
 Cited by
Relationships between Pork Quality Traits and Growth Factor Concentrations in Serum and Longissimus dorsi Muscle before and at Slaughter in Female Market Pigs,;;;;;

Journal of Animal Science and Technology, 2013. vol.55. 2, pp.95-101 crossref(new window)
Blair H. T., S. N. McCutcheon, D. D. S. Mackenzie, P. D. Gluckman and J. E. Ormsby. 1987. Variation in plasma concentration of insulin-like growth factor-I and its covariation with liveweight in mice. Aust. J. Biol. Sci. 40:287-293.

Boney, C. M., B. M. Moats-Staats, A. D. Stiles and A. J. D'Ercole. 1994. Expression of insulin-like growth factor-I (IGF-I) and IGF-binding proteins during adipogenesis. Endocrinology. 135:1863-1868. crossref(new window)

Boney, C. M., P. A. Gruppuso, R. A. Faris and A. R. Frackelton Jr. 2000. The critical role of Shc in insulin-like growth factor-Imediated mitogenesis and differentiation in 3T3-L1 preadipocytes. Mol. Endocrinol. 14:805-813. crossref(new window)

Brameld, J. M., J. L. Atkinson, J. C. Saunders, J. M. Pell, P. J. Buttery and R. S. Gilmour. 1996. Effects of growth hormone and dietary proteins intake on insulin-like growth factor I and growth hormone receptor mRNA expression in porcine liver, skeletal muscle, and adipose tissue. J. Anim. Sci. 74:1832-1841. crossref(new window)

Buonomo, F. C. and J. Klindt. 1993. Ontogeny of growth hormone (GH), insulin-like growth factors (IGF-I and IGFII) and IGF binding protein-2 (IGFBP-2) in genetically lean and obese swine. Domest. Anim. Endocrinol. 10:257-265. crossref(new window)

Burr, J. G., G. Dreyfuss, S. Penman and J. M. Buchanan. 1980. Association of the src gene product of Rous sarcoma virus with cytoskeletal structures of chicken embryo fibroblasts. Proc. Natl. Acad. Sci. USA. 77:3484-3488. crossref(new window)

Clore, J. N. 1995. Dehydroepiandrosterone and body fat. Obes. Res. Suppl. 4:613S-616S.

Coleman, M. E., L. Russell and T. D. Etherton. 1994. Porcine somatotropin (pSTt) increases IGF-I Mrna abundance in liver and subcutaneous adipose tissue but not in skeletal muscle ofg rowing pigs. J. Anim. Sci. 72:918-924. crossref(new window)

Corino, C., G. Oriani, L. Pantaleo, G. Pastorelli and G. Salvatori. Influence of dietary vitamin E supplementation on 'heavy' pig carcass characteristics, meat quality, and vitamin E status. J. Anim. Sci. 77:1755-1761.

Daughaday, W. H. and P. Rotwein. 1989. Insulin-like growth factor I and II. Peptide, messenger ribonucleic acid gene structures, serum, and tissue concentration. Endocr. Rev. 10:68-91. crossref(new window)

Florini, J. R. and D. Z. Ewton. 1988. Actions of transforming growth factor-beta on muscle cells. J. Cell. Physiol.135:301-8. crossref(new window)

Florini, J. R., D. Z. Ewton and K. A. Magri. 1991. Hormones, growth factors, and myogenic differentiation. Annu. Rev. Physiol. 53:210-216.

Florini. J. R., D. Z. Ewton, and S. S. Coolican. 1996. Growth hormone and the insulin-like growth factor system in myogenesis. Endocr. Rev. 17: 481-517.

Gluckman, P. D., R. G. Douglas, B. H. Breier, J. L. McCall, B. Parry and J. H. Shaw. 1991. Effects of recombinant IGF-I on protein and glucose metabolism in rTNF-infused lambs. Am. J. Physiol. 261:606-612.

Jones, J. I. and D. R. Clemmons. 1995. Insulin-like growth facotrs and their binding proteins: biological actions. Endocr. Rev. 16:3-34.

Lamberson, W. R., J. A. Sterle and R. L. Matteri. 1996. Relationships of serum insulin-like growth factor II concentrations to growth, compositional and reproductive traits of swine. J. Anim. Sci. 74:1753-1756. crossref(new window)

Lamberson, W. R., T. J. Safranski, R. O. Bates, D. H. Keisler and R. L. Matteri. 1995. Relationships of serum insulin-like growth factor I concentrations to growth, composition, and reproductive traits of swine. J. Anim. Sci. 73:3241-3245. crossref(new window)

Lee, C. Y. and D. M. Henrick. 1990. Comparison of various acidic treatments of bovine serum on insulin-like growth factor-I immunoreactivity and binding activity. J. Endocrinol. 127: 139-148. crossref(new window)

Lee, C. Y., C. S. Chung and F. A. Simmen. 1993. Ontogeny of the porcine insulin-like growth factor system. Mol. Cell. Endocrinol. 93:71-80. crossref(new window)

Lee, C. Y., H. H. Head, C. R. Feinstein, J. Hayden and F. A. Simmen. 1995. Endocrine changes and circulating insulin-like growth factors in newborn calves fed colostrum, milk, or milk replacer. Asian-Aust. J. Anim. Sci. 8:51-58.

Marques, B. G., D. B. Hausman, A. M. Latimer, K. M. Kras, B. M. Grossman and R. Y. Martin. 2000. Insulin-like growth factor I mediates high-fat diet-induced adipogenesis in osborne-mendetl rats. Am. J. Physiol. Regulatory Integrative Comp. Physiol. 278:654-662.

McGuinness, M. C. and L. A. Cogburn. 1990. Measurement of developmental changes in plasma insulin-like growth factor-I levels of broiler chickens by radioreceptor assay and radioimmunoassay. Gen. Comp. Endocrinol.79:446-458. crossref(new window)

Nissley, S. P. and M. M. Rechler. 1984. Insulin-like growth factors: biosynthesis, receptors, and carrier proteins. In: (Ed. Li CH) Hormonal Proteins and Peptides, Academic Press, New York, 12:127-201.

O'Quinn, P. R,. B. S. Andrews, R. D. Goodband, J. A. Unruh, J. L. Nelssen, J. C. Woodworth, M. D. Tokach and K. Q. Owen. Effects of modified tall oil and creatine monohydrate on growth performance, carcass characteristics, and meat quality of growing-finishing pigs. J. Anim. Sci.78:2376-2382. crossref(new window)

Owens, P. C., K. L. Gatford, P. E. Walton, W. Morley and R. G. Campbell .1999. The relationship between endogenous insulin-like growth factors and growth in pigs. J. Anim. Sci. 77:2098-2103. crossref(new window)

Peng, M., M. F. Palin, S. Veronneau, D. LeBel and G. Pelletier. 1997. Ontogeny of epidermal growth factor (EGF), EGF receptor (EGFR) and basic fibroblast growth factor (bFGF) mRNA levels in pancreas, liver, kidney, and skeletal muscle of pig. Domes. Anim. Endocrinol. 14:286-294. crossref(new window)

Recee, E. A., A. Wiznitzer, E. Le, C. J. Homko, H. Behrman and E. M. Spencer. 1994. The relation between human fetal growth and fetal blood levels of insulin-like growth factors I and II, their binding proteins, and receptors. Obstet. Gynecol. 84:88-95.

SAS. 1995. SAS/SAT Software for PC. Release 6.11, SAS Institute. Cary, NC, USA.

Szabo, C., A. J. Jansman, L. Babinszky, E. Kanis and M. W. Verstegen. 2001. Effect of dietary protein source and lysine:DE ratio on growth performance, meat quality, and body composition of growing-finishing pigs. J. Anim. Sci. 79:2857-2865. crossref(new window)

Wise, T., J. Klindt and F. C. Buonomo. 1995. Obesity and dehydroepiandrosterone/ dehydroepiandrosterone sulfate relationship in lean, obese, and meat-type corss-bred boars: response to porcine growth hormone. Endocrinology. 136:3310-3317. crossref(new window)

Yang S. W. and J. S. Yu. 2000. Relationship of insulin-like growth factor-I, insulin-like growth factor binding protein-3, insulin, growth hormone in cord blood and maternal factors with birth height and birthweight. Pediatr. Int.42:31-36. crossref(new window)

Yoon, J., M. S. Rhee, D. S. Seo, B. C. Kim and Y. Ko. 2001. Monitoring of blood cytokines by PIT-1 genotype in day 150 male pigs. Asian-Aust. J. Anim. Sci. 14:1659-1664.

Yun, J. S., W. J. Kang, D. S. Seo, S. S. Park, K. C. Hong, C. Y. Lee and Y. Ko. 2001. Association of endocrine factors (insulin-like growth factor-II and binding protein-3) with litter size in pigs. Asian-Aust. J. Anim. Sci. 14:307-315.

Zappelli F., D. Willems, S. Osada, S. Ohno, W. C. Wetsel, M. Molinaro, G. Cossu and M. Bouche. 1996. The inhibition of differentiation caused by TGF-beta in fetal myoblasts is dependent upon selective expression of PKCtheta: a possible molecular basis for myoblast diversification during limb histogenesis. Dev. Biol. 180:156-164. crossref(new window)