JOURNAL BROWSE
Search
Advanced SearchSearch Tips
Interaction between Iron and Vitamin A in Broilers
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Interaction between Iron and Vitamin A in Broilers
Zhang, Chunshan; Jiang, Junfang; Suo, Landi; Wei, Jianmin;
  PDF(new window)
 Abstract
A (FeVA) experiment with repeats was designed to study the interaction between iron and vitamin A in broilers. 504 broilers were divided into 9 groups (50% males, 50% femals), each group with 4 repeats. Iron supplemental amount was 0, 30 and 60 mg/kg; Vitamin A supplemental amount was 750, 1,500 and 2,700 IU/kg. Iron concentration in liver, serum, tibia and duodenum and vitamin A concentration in liver and serum were measured, and erythrocyte count was also observed. Results showed with the increase of dietary supplemental iron levels, vitamin A concentration in liver significantly decreased lineally (p<0.05) (0.861, 0.671, 0.639 mg/100 g at the end of 4th week; 0.900, 0.765, 0.739 mg/100 g at the end of 7th week), and vitamin A concentration in serum significantly increased lineally (p<0.05) (82.725, 97.842, at the end of 4th week; 62.288, 91.900, at the end of 7th week), meaning iron could promote the mobilization of vitamin A from liver to serum. With the increase of dietary supplemental vitamin A levels, liver iron concentration decreased and serum iron concentration increased, vitamin A could promote the mobilization of iron from liver to blood. Iron concentration in Duodenum and tibia and erythrocyte count increased significantly with higher dietary vitamin A supplementation (p<0.01), vitamin A could promote iron absorption, iron mobilization from liver to target tissues and erythropoiesis. Effects of the interaction between iron and vitamin A on vitamin A concentrations in liver and serum, iron concentration in tibia and erythrocyte count were significant (p<0.05).
 Keywords
Broilers;Iron;Vitamin A;Interaction;
 Language
English
 Cited by
 References
1.
Beynen, A. C., K. W. Sijtsman, G. J. Van Den Burg, A. G. Lemmens and C. E. West. 1991. Iron metabolism in vitamin A deficiency. Trace Elements in Man and Animals. 7:215-216.

2.
Beynen, A. C., K. W. Sijtsman, G. J. Van Den Borg, A. G. Lemmens and C. E. West. 1992. Iron status in rats fed a purified diet without vitamin A. Biological Trace Element research. 35(1):81-84. crossref(new window)

3.
Bloem, M. W., M. Wedel, E. Van Agtmaal, A. J. Speek, S. Saowakontha and W. H. P. Schreurs. 1990. Vitamin A intervention: short term effects of a single, oral massive dose on iron metabolism. Am. J. Clin. Nutr.. 51:76-79.

4.
Bloem, M. W., M. Wedel, R. J. Egger, A. J. Speed, J. Schrijver and S. Saowakontha. 1989. Iron metabolism and vitamin A deficiency in children in Northeast Thailand. Am. J. Clin. Nutr. 50:332-338.

5.
Chinese Academy of Agricultural Science. 1998. Nutrition Requirements of Broiler. National Agriculture Press, BeiJing, China.

6.
Garcia Casal, M. N. M. Layrisse, L. Solano, M. A. Barom, G. Azguello and D. Lovera. 1998. Vitamin A and beta-carotene can improve nonheme iron absorption from rice, wheat and corn by humans. J. Nutr. 128(3):646-650.

7.
Han, Z. K. L., L. Zhi and W. K. Wang. 1995. Analysis of Hb Concentrationpages and Red Cell Count. In: Guide for Physical Experiment of Animals (Ed. Z. K. Hang). Agricultural University Press, Bei Jing, China. pp. 14-20.

8.
Hong, C. B., S. M. Zhu and Z. Y. Liu. 1994. The function of vitamin A in improving the hemoglobin concentration and iron status of middle school students in mountain area. Acta Nutrimenta Sinica. 16(1):29-32.

9.
Layrisse, M., M. N. Garcia Casal, L. Solano, M. A. Barom and G. Azguello. 1998. Vitamin A reduces the inhibition of iron absorption by phytates and polyphenols. Food and Nutrition Bulletin. 19(1):3-5.

10.
Li, Y. Y., Y. P. Wang and Y. Yan. 1999. Effects of vitamin A on hematopoietic microenvironment. Acta Nutrition Sinica. 21(4):388-392.

11.
Mejia, L. A. and F. Chew. 1988. Hematological effect of supplementing anemic children with vitamin A alone and in combination with iron. Am. J. Clin. Nutr. 48:595-600.

12.
Mejia, L. A., R. E. Hodges and R. B. Rucker. 1979. Clinical signs of anemia in vitamin A deficient rats. Am. J. Clin. Nutr. 32:1439-1444.

13.
Mejia, L. A., R. E. Hodges and R. B. Rucker. 1979. Role of vitamin A in the absorption, retention and distribution of iron in the rat. J. Nutr. 109:129-137.

14.
Mejia, L. A. and G. Arroyave. 1982. The effect of vitamin A fortification of sugar on iron metabolism in preschool children in Guatemala. Am. J. Clin. Nutr. 36:87-93.

15.
Muhilal, O. D., Y. R. Idjradinaa and D. Karyadi. 1988. Vitamin A fortified monosodium glutamate and health, growth, and survival of children: a controlled field trial. Am. J. Clin. Nutr. 48:1271-1276.

16.
Munoz, E. C., J. L. Rosado, P. Lopez, H. C. Furr and L. H. Allen. 2000. Iron and zinc supplementation improves indicators of vitamin A status of Mexican preschoolers. Am. J. Clin. Nutr. 71(3):789-794.

17.
Roodenburg, A. J. C., C. E. West and A. C. Beynen. 1994. Comparison between time dependent changes in iron metabolism of rats as induced by marginal deficiency of either vitamin A of iron. Br. J. Nutr. 71:687-699. crossref(new window)

18.
Roodenburg, A. J. C., A. M. M. Pelt Van, C. E. West, A.C. Beynen and A. M. M. Van Pelt. 1996. Effect of vitaminA supplementation for 3 days on iron metabolism, liver function indicator enzymes and differential cell counts in bone marrow of rats with severe vitamin A deficiency. Nutr. Res. 16(11-12):1933-1941. crossref(new window)

19.
Roodenburg, A. J. C., C. E West, R. Hovenier and A. C. Beynen. 1996. Supplemental Vitamin A Enhances the recovery from iron deficiency in rats with chronic vitamin A deficiency. Br. J. Nutr. 75:623-636. crossref(new window)

20.
Rosales, F. J., J. T. Jiang, D. T. Pivero, K. M. Frikson, J. L. Beard and A. C. Ross. 1999. Iron deficiency in young rats alters the distribution of vitamin A between plasma and liver and between hepatic retinal and retinyl esters. J. Nutr. 129(6):1223-1228.

21.
SAS Institute Inc. 1989. SAS : Version 6.12 th edn. SAS Institute Inc., Cary, NC 27513, USA.

22.
Schultink, W., M. Merzenich, R. Gross, R. Shrimpton and D. Dillon. 1997. Effects of iron-zinc supplementation on the iron, zinc, and vitamin A status of anaemic preschool children in Indonesia. Food and Nutrition Bulletin. 18(4):311-317.

23.
Schweigert, F. J., H. Gurrler, A. Baumane, M. Wahren and M. Leo. 2000. Effect of iron supplemetation on plasma levels of vitamin A, E and C in piglets. Livest. Prod. Sci. 63(3):297-302. crossref(new window)

24.
Sijtsma, K. W., G. J. Vandenberg, A. G. Lemmens, K. W. Sijtsma and A. C. Beynen. 1993. Iron status in rats on diets containing marginal amounts of vitamin A. Br. J. Nutr. 70(3):777-785. crossref(new window)

25.
Staab, D. B., R. E. Hodges, W. K. Metcalf and J. L. Smith. 1984. Relationship between vitamin A and iron in the liver. J. Nutr. 57:11-18.

26.
Suharno, D., C. E. West, Muhilal, M. H. G. M. Logman, F. G. Waart and D. Karyadi. 1992. Cross-sectional study on the iron and vitaminA status of pregnant women in west Java, Indonesia. Am. J. Clin. Nutr. 56(6):988-993.

27.
Wang, Y. and Y. H. Bo. 1996. Iron. In: Trace Elements in life Science, 2nd Ed. (Ed. Y. wang, R. Y. Tang, H. B. Xu and X. M. Luo). China Measuring Press, BeiJing, China. pp. 241-244.

28.
Wolde-Gebriel, Z., C. E. West, A. S. Haile Gevru, Tadesse, T. Fisseha, P. Gabre, G. Ayana and J. G. A. J. 1993. Interrelationship between vitamin A, iodine and iron status in school children in Shoa Region, Central Ethiopia. Br. J. Nutr. 70:593-607. crossref(new window)