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Comparing Bio-efficacy of Liquid DL-methionine Hydroxy Analogue Free Acid with DL-methionine in Broiler Chickens
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 Title & Authors
Comparing Bio-efficacy of Liquid DL-methionine Hydroxy Analogue Free Acid with DL-methionine in Broiler Chickens
Mandal, A.B.; Elangovan, A.V.; Johri, T.S.;
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The present experiment was conducted to assess the efficacy of methionine hydroxy analogue free fatty acid (MHAFA) in comparison to DL-methionine (DL-Met) utilizing day-old commercial broiler chicks (n=300). The chicks were randomly distributed into 30 groups of 10 chicks each. Three dietary treatments, viz. D1-maize-soybean meal based basal diet (Control), D2- control diet supplemented with DL- methionine to meet its requirements and D3-control supplemented with MHA-FA @ 1.54 times of DL-methionine used in D2, were formulated. Each dietary treatment was offered to 10 replicated groups of chicks following completely random design (CRD). The chicks fed on supplemental DL-Met had significantly higher (p<0.01) gain in body weight, followed by MHA-FA group and control during 0-3 weeks of age. During overall growth period (0-6 weeks), chicks in DL-Met and MHA-FA groups grew better (p<0.01) than those in control. Feed conversion ratio (FCR) improved (p<0.01) on supplementation of either DL- Met or MHA-FA in the basal (Control) diet during 0-3 weeks of age. The FCR for overall period, however, did not differ statistically (p>0.05) amongst the treatments. The eviscerated yields emanated from diets with DL-Met or MHA-FA were higher (p<0.01) than that in Control. Abdominal fat pad was also more (p<0.01) in broilers fed control diet than in DL-Met or MHA-FA supplemented group. Breast yield was higher (p<0.05) in MHA-FA fed broilers than those fed DL-methionine supplemented or un-supplemented diets. The efficacy of MHA-FA in comparison to DL-Met for growth was 62.11, 64.82 and 63.88% and for feed efficiency was 62.98, 67.73 and 64.01% at 0-3, 3-6 and 0-6 weeks of age, respectively, while it was 65.85, 71.40 and 67.49% for eviscerated yield, abdominal fat pad reduction and breast yield at 6 weeks of age, respectively.
MHA-FA;DL-methionine;Broiler;Growth Performance;Carcass Traits;
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AOAC. 1990. Official Methods of Analysis, 15th Ed. Association of Official Analytical Chemists, Arlington, Virginia, USA.

Bertram, H. L., E. J. Van Weerden and J. B. Schutte. 1991. DLmethionine and DL-methionine hydroxy analogue compared: There is a difference in biological activity in broiler diets. Misset World Poultry vol. 7:2, 13, 15.

Brennan, J. J. 1998. Efficacy of liquid MHA-FA as compared to DL-methionine on performance and carcass quality of broiler chickens. Project No. 40351, Shur-Gain Agresearch, Canada (Source: Feed back facts & figures, Feed additives, Poultry 7, Degussa-Huls).

Christensen, A. C. and J. O. Anderson. 1980. Factors affecting efficacy of methionine hydroxy analogue for chick fed practical diets. Poult. Sci. 59:2485-2491.

Danner, E. E. and W. Bessei. 2002. Effectiveness of liquid DLmethionine hydroxy analogue-free acid (DL-MHA-FA) compared to DL-methionine on performance of laying hens. Arch. Geflugelk 66:(3),97-101.

Duncan, D. B. 1955. Multiple range and F tests. Biometrics 11:1-42. crossref(new window)

Greger, G. R., J. R. Couch and H. L. Ernst. 1968. Methionine hydroxy analogue and L-methionine in broiler diets. Poult. Sci. 47:229-232.

Harms, R. H. and R. E. Buresh. 1985. Recent poult studies comparing methionine availability from various sources, In: Proceedings Florida Nutrition Conference, pp. 41-45 (Gainesville, University of Florida).

Harvey, W. R. 1975. Least square analysis of data with unequal subclass numbers. Agric Research Service, United State, Deptt. of Agriculture.

Huyghebaert, G. and P. J. W. Van Schagen. 1989. Relative biopotency of methionine sources for broilers, as measured by means of a multi-exponential regression model, In: IRTA,Barcelona, Proceedings 7th European Symposium on Poultry Nutrition, loret de Mar, Spain.

Kirchgessner, M. and H. Steinhart. 1984. Biological effectiveness of DL-methionine-Na and DL-2-hydroxy-4-methylthiobutyric acid with broilers. Archiv fiir Gefliigelkunde, 48:45-51.

Larbier, M. 1988. A comparative study on the digestibility of methionine hydroxy analogue (M.H.A.) and of DL-methionine on adult cocks, in: (Ed. Y. Yamada) Proceedings XVIII World’s Poultry Congress, September 4-9, Nagoya, Japan, pp. 823-825 (Japanese Poultry Science Association).

Lemme, A., D. Hoehler, J. J. Brennan and P. F. Mannion. 2002.Relative Effectiveness of Methionine Hydroxy Analog Compared to DL-methionine in Broilers Chickens. Poult. Sci.81:838-845.

Llames, C. R. and J. Fontaine. 1994. Determination of amino acids in feeds: Collaborative study. J. Assoc. Off. Anal. Chem. Int. 77:1362-1402.

Lu, J. J., C. W. Huang and R. G. R. Chou. 2003. The effects of DLMethionine hydroxyl analogue on growth performance, contents of serum amino acids and activities of digestive proteases in broilers. Asian-Aust. J. Anim. Sci. 16:714-718.

Mannion, P. F. 1999. A comparison of the bioefficacy of diluted DL-methionine (65%) or liquid MHA-FA as compared to pure DL-methionine in broiler chicks. Report No. 03.53.99002, Queensland Poultry Research and Development Centre, Australia. (Source: Feed back facts & figures, Feed additives, Poultry 10, Degussa-Huls).

Naumann, C., R. Bassler, R Seibold and C. Barth. 1997. Methodenbuch Band III. VDLUFA-Verlag, Darmstadt, Germany.

Noll, S. L., P. E. Waibel, R. D. Cook and J. A. Witmer. 1984. Biopotency of methionine sources for young turkeys. Poult. Sci. 63:2458-2470.

Reid, B. L., A. Madrid and P. M. Maiorino. 1982. Relative biopotency of three methionine sources for laying hens. Poult. Sci. 61:726-730.

Romoser, G. L., P. L. Wright and R. B. Grainger. 1976. An evaluation of the L-methionine activity of the hydroxy analogue of methionine. Poult. Sci. 55:1099-1103.

Snedecor, G. W. and W. G. Cochran. 1989. Statistical Methods. 8th Ed. Iowa State University press, Ames, Iowa.

Thomas, O. P., S. D. Crissey, E. H. Bossard and M. B. Soverns. 1983. An evaluation of DL-methionine and related compounds. Proceedings Maryland Nutrition Conference for Feed Manufactureres, 26-31.

Thomas, O. P., C. Tamplin, S. D. Crissey, E. H. Bossard and A. Zuckerman. 1991. An evaluation of methionine hydroxy analog free acid using a non linear(exponential) bioassay. Poult. Sci. 70:605-610.

Uzu, G. 1986. Nutritional efficacy of DL-methionine, Dmethionine and DL-methionine hydroxy analogue acid in a corn soybean meal lupin diet, in: (M. Larbie) Proceedings 7th European Poultry Conference, August 24-28, Paris, France, pp. 612-615 (French Branch of WPSA).

Van Weerden, E. J., H. L. Bertram and J. B. Schutte. 1982. Comparison of DL-methionine, DL-methionine-Na, DLmethionine hydroxy analogue-Ca, and DL-methionine hydroxy analogue free acid in broilers by using a crystalline amino acid diet. Poult. Sci. 61:1125-1130.

Van Weerden, E. J., J. B Schutte and H. L. Bertram. 1983. DLmethionine and DL-methionine hydroxy free acid in broiler diets. Poult. Sci. 62:1269-1274.

Waldroup, P. W., C. J. Mabray, J. R. Blackman, P. J. Slagter, R. J. Short and Z. R. Johnson. 1981. Effectiveness of the free acid of methionine hydroxy analogue as a methionine supplement in broiler diets. Poult. Sci. 60:438-443.