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Plasma Leptin and Performance of Purebred and Backcrossed Hereford throughout Grazing and Feedlot Fattening
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Plasma Leptin and Performance of Purebred and Backcrossed Hereford throughout Grazing and Feedlot Fattening
Vega, R.A.; Hidari, H.; Matsunaga, N.; Kuwayama, H.; Manalo, D.D.; Lee, H.G.; Hata, H.;
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In a herd of 24 spring-born steers, plasma leptin and performance of selected purebred (n=5) and backcrossed Hereford (n=5) were compared in a year-round summer grazing and winter feedlot fattening. Bimonthly blood collection and body weight measurement were accomplished. The plasma samples were analyzed for leptin, insulin, total cholesterol, triglyceride, NEFA and glucose. The experimental design utilized one-way ANOVA with breed as the treatment. The purebred obtained higher plasma NEFA (p<0.001) compared to backcross, regardless of seasonal feeding systems (SFS). The backcross showed gradual increase and nonresponsiveness of plasma leptin to SFS. During summer grazing, attenuation of plasma leptin and sudden elevation when shifted to winter feedlot fattening were observed in purebred. Plasma leptin obtained linear relationship with body weight of purebred (r=0.53;p<0.001) and backcrossed Hereford (r=0.49; p<0.01). The purebred and backcrossed Hereford, when shifted to summer grazing, resulted to sustained and restricted daily gain, respectively. Therefore, cattle breeds of higher growth potential exhibit significant elevation of plasma leptin after 400 kg BW, when animal starts to deposit significant body fat.
Feedlot;Grazing;Hereford;Japanese Black;Leptin;
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Asian-Australasian Journal of Animal Sciences, 2007. vol.20. 1, pp.41-44 crossref(new window)
Arner, P. 2000. Obesity-a genetic disease of adipose tissue? Br. J. Nutr. 83:S9-S16.

Blache, D., R. L. Tellam, L. M. Chagas, M. A. Blackberry, P. E. Vercoe and G. B. Martin. 2000. Level of nutrition affects leptin concentrations in plasma and cerebrospinal fluid in sheep. J. Encrinol. 165:625-637.

Blum, W. F., P. Englaro, S. Hanitsch, A. Juul, N. T. Hertel, J. Muller, N. E. Skakkebaek, M. L. Heiman, M. Bierkett, A. M. Attanasio, W. Keiss and W. Rascher. 1997. Plasma leptin levels in healthy children and adolescent: dependence on body mass index, body fat mass, gender pubertal stage and testosterone. J. Clin. Endocrinol. Metab. 82:2904-2910.

Christopherson, R. J. 1976. Effect of prolonged cold and outdoors winter environment on apparent digestibility in sheep and cattle. Can. J. Anim. Sci. 56:201-212.

Comuzzie, A. G and D. B. Allison. 1998. The search for human obesity genes. Science 280:1374-1377.

Curtis, S. E. 1983. Thermal-environmental requirements. In: Environmental Management in Animal Agriculture (Ed. G. I. Christison, K. W. Kelley and W. O. Wilson) Iowa State University Press, Ames, Iowa. pp. 127-133.

Dimarco, N. M., D. C. Beitz and G. B. Whitehurst. 1981. Effect of fasting on free fatty acid, glycerol and cholesterol concentrations in blood plasma and lipoprotein lipase activity in adipose tissue of cattle. J. Anim. Sci. 52:75-82.

Ehrhardt, R. A., R. M. Slepetis, J. Siegal-Willot, M. E. Van Amburgh, A. W. Bell and Y. R. Boisclair. 2000. Development of specific radioimmunoassay to measure physiological changes of circulating leptin in cattle and sheep. J. Endocrinol. 166:519-528.

Frederich, R. C., A. Hamann, S. Anderson, B. Lollman, B. B. Lowell and J. S. Flier. 1995. Leptin levels reflect body lipid in mice: evidence for diet-induced resistance to leptin. Nature Medicine 1:1311-1314.

Hata, H and H. Hidari. 2001. Characteristics in deposition of body components and endocrine system in grazing steers. Proceedings of Japanese Society of Animal Nutrition and Metabolism 45:75-91.

Kweon, O. K., H. Ono, K. Osasa, M. Onda, K. Oboshi, H. Uchisugi, S. Kurosawa, H. Yamashita and H. Kanagawa. 1986. actors affecting serum total cholesterol level of lactating Holstein cows. Jpn. J. Vet. Sci. 48:481-486.

Levin, B. E. and R. E. Keesey. 1998. Defense of differing body weight set points in diet-induced obese and resistant rats. Am. J. Physiol. 43:R412-R419.

Matsuzaki, M., S. Takizawa and M. Ogawa. 1997. Plasma leptin, metabolite concentration and carcass characteristic of Japanese Black, Japanese Brown and Holstein steer. J. Anim. Sci. 75:3287-3293.

Old, C. A. and W. N. Garret. 1987. Effects of energy intake on energetic efficiency and body composition of beef steers differing in size at maturity. J. Anim. Sci. 65:1371-1380.

O’ Kelly, J. C. 1972. Plasma lipid changes in genetically different types of cattle during hyperthermia. Comp. Biochem. Physiol. 44A:313-320.

Robert, C., M. Palin, N. Coulombe, C. Roberge, F. G. Silverside, B. F. Benkel, R. M. Mckay and G. Pelletier. 1998. Backfat in pigs is positively associated with leptin mRNA levels. Can. J. Anim. Sci. 78:473-482.

Vega, R. A., H. G. Lee, N. Matsunaga, H. Kuwayama and H. Hidari. 2002. Age-related changes in plasma leptin from early growing to late finishing stages of castrated Holstein steers: utilizing multi-species leptin RIA. Asian-Aust. J. Anim. Sci. 15(5):725-731.

Vega, R.A., H. Hidari, H. Kuwayama, M. Suzuki and D. D. Manalo. 2004. The relationship of plasma leptin, backfat thickness and TDN intake across finishing stage of Holstein steers. Asian-Aust. J. Anim. Sci. 17(3):330-336.

Verde, L. S. and A. Trenkle. 1987. Concentrations of hormones in plasma from cattle with different growth potentials. J. Anim. Sci. 64(2):426-432.

West, D. B., C. N. Boozer, D. L. Moody and R. L. Atkinson. 1992. Dietary obesity in nine inbred mouse strain. Am. J. Physiol. 31:R1025-R1032.

Young, B. A. 1981. Cold stress as it affects animal production. J. Anim. Sci. 52:154-163.