Advanced SearchSearch Tips
Cholesterol Removal from Homogenized Milk with Crosslinked β-cyclodextrin by Adipic Acid
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Cholesterol Removal from Homogenized Milk with Crosslinked β-cyclodextrin by Adipic Acid
Han, Eun-Mi; Kim, Song-Hee; Ahn, Joungjwa; Kwak, Hae-Soo;
  PDF(new window)
The present study was carried out to develop crosslinking of -cyclodextrin (-CD) using adipic acid, and to determine the optimum conditions of different factors (-CD concentration, mixing temperature, mixing time and mixing speed) on cholesterol reduction from homogenized milk. Crosslinked -CD was prepared with adipic acid. When the milk was treated with different conditions, the cholesterol removal rate was in the range of 92.1 to 93.1% with 1% -CD addition, which were not significantly different among treatments. After cholesterol removal from milk, the used crosslinked -CD was washed for cholesterol dissociation and reused. For recycling study, the cholesterol removal rate in the first trial was 92.5%, which was mostly same as that using new crosslinked -CD. With repeated ten time trials using same sample, 81.4% of cholesterol was removed from milk. Therefore, the present study indicated that the optimum conditions for cholesterol removal using crosslinked -CD were 1% -CD addition and 10 min mixing with 400 rpm speed at 5 with over 90% cholesterol removal. In addition, crosslinked -CD made by adipic acid resulted in the effective recycling efficiency.
Crosslinked -CD;Cholesterol Removal;Homogenized Milk;Recycling;
 Cited by
가교화 β-Cyclodextrin과 식물성 Sterol을 이용한 콜레스테롤 저하 마요네즈의 연구,정태희;하현지;안정좌;곽해수;

한국축산식품학회지, 2008. vol.28. 2, pp.211-217 crossref(new window)
Cholesterol Removal from Lard with Crosslinked ${\beta}$-Cyclodextrin,;;;

아세아태평양축산학회지, 2007. vol.20. 9, pp.1468-1472 crossref(new window)
Comparison of Cholesterol-reduced Cream Cheese Manufactured Using Crosslinked β-Cyclodextrin to Regular Cream Cheese,;;;;

아세아태평양축산학회지, 2008. vol.21. 1, pp.131-137 crossref(new window)
Entrapment of Milk Nutrients during Cholesterol Removal from Milk by Crosslinked β-Cyclodextrin,;;;;

한국축산식품학회지, 2009. vol.29. 5, pp.566-572 crossref(new window)
Qualitative and Quantitative Analyses of Volatile Compounds in Cream Cheese and Cholesterol-removed Cream Cheese Made from Whole Milk Powder,;;;;

한국축산식품학회지, 2011. vol.31. 6, pp.879-885 crossref(new window)
Adams, M. L., D. M. Sullivan, R. L. Smith and E. F. Richer. 1986. Evaluation of direct saponification method in determination of cholesterol in meats. J. Assoc. Anal. Chem. 69:844-846.

Carleton, R. A., L. Finberg, J. Flora, D. S. Goodman, S. M. Grundy, S. Haven, G. T. Hunter, D. Kritchevsky, R. M. Lauer, R. V. Luepker, A. G. Ramirez, L. Van Horn, W. B. Stason and J. Stokes. 1991. Report of the expert panel on population strategies for blood cholesterol reduction. Circulation 83:2154-2232.

Fleche, G. 1985. Chemical modification and degradation of starch. In: (Ed. G. M. Van Beynum and J. A. Roel) Starch conversion technology. Dekker, New York, NY, USA, pp. 73-99.

Grundy, S. M., D. Brheimer, H. Blackburn, W. V. Brown, P. O. Kwiterovich, F. Mattson, G. Schonfeld and W. H. Weidman. 1982. Rational of the diet-heart statement of the American Heart Association Report of the Nutrition Committee. Circulation 65:839A-854A.

Gurr, M. 1992. Dietary lipids and coronary disease: old evidence, new perspective and progress. Lipid Res. 31:195-243.

Hamerstrand, G. E., B. T. Hofreiter and C. L. Mehltretter. 1959. Determination of the extent of reaction between epichlorohydrin and starch. 37:519-524

Hosney, C. 1986. Principle of cereal science and technology, AACC. St. Paul, MN, USA.

Hwang, J. H., S. J. Lee and H. S. Kwak. 2005. Change of properties and cholesterol lowering effect in evening primrose oil-added and cholesterol-reduced milk. Asian-Aust. J. Anim. Sci. 18:1041-1047.

Kim, J. J., S. H. Yoo, J. Ahn, W. M. Jeon and H. S. Kwak. 2005. The effect of evening primrose oil on chemical properties and lowering blood cholesterol in nutraceutical Cheddar cheese. Arch. Pharm. Res. (in press).

Kim, S. H., J. Ahn and H. S. Kwak. 2004. Crosslinking of $\beta$-cyclodexrin on cholesterol removal from milk. Arch. Pharm. Res. 27:1183-1187.

Kwak, H. S., H. J. Ahn and J. Ahn. 2005. Development of phytosterol ester-added Cheddar cheese for lowering blood cholesterol. Asian-Aust. J. Anim. Sci. 18:267-276.

Kwak, H. S., S. H. Kim, J. H. Kim, H. S. Choi and J. M. Kang. 2004. Immobilized $\beta$-cyclodextrin as a simple and recyclable method for cholesterol removal in milk. Arch. Pharm. Res. 27:873-877.

Kwak, H. S., C. S. Jung, S. Y. Shim and J. Ahn. 2002. Removal of cholesterol from Cheddar cheese by $\beta$-cyclodextrin. Agric. Food Chem. 50:7293-7298.

Kwak, H. S., H. M. Suh, J. Ahn and H. J. Kwon. 2001. Optimization of $\beta$-cyclodextrin recycling process for cholesterol removal in cream. Asian-Aust. J. Anim. Sci. 14:548-552.

Lee, J. S., Z. Ustunol and D. M. Smith. 1993. Cholesteorl removal from cream using $\beta$-cyclodextrin and derivatives. J. Dairy Sci. 76(Suppl.1):143 (Abstr.).

Lee, S. J., J. S. Hwang, S. Lee, J. Ahn and H. S. Kwak. 2005. Property changes and cholesterol lowering effect in evening primrose oil-added and cholesterol-reduced yogurt. J. Dairy Sci. (in press).

Luallen, E. T. 1985. Starch as a functional ingredient, Food Technol. 39:59-63.

Makoto, K., O. Akio and S. Reijiro. 1992. Cholesterol removal from animal fat with cyclodextrin in inclusion. Honnen LTD., assignee, Japan Pat. No. 4:168,198.

Micich, T. J. 1990. Behaviors of polymer supported digitonin with cholesterol in the absence and presence of butter oil. J. Agric. Food Chem. 38:1839-1843.

Nagamoto, S. 1985. Cyclodextrin-expanding the development of their functions and applications. Chem. Econ. Eng. Rev. 17:28-34.

Oakenfull, D. G. and G. S. Sihdu. 1991. Cholesterol reduction. Commonwealth scientific and industrial research organization. Int. Pat. No. 91/11114.

Oh, H. I., E. J. Jang and H. S. Kwak. 1998. Conditions of the removal of cholesterol from milk by treatment with saponin. Korean J. Dairy Sci. 20:253-260.

Pyorala, K. 1987. Dietary cholesterol in relation to plasma cholesterol and coronary heart disease. Am. J. Clin. Nutr. 45:1176-1184.

SAS$^{\circledR}$. 1985. Users Guide: Statistics, Version 5 Edition. SAS Inst., Inc., Cary, NC, USA.

Schroder, B. G. and R. J. Baer. 1990. Consumer evaluation of reduced-cholesterol butter. Food Technol. Oct, 104-107.

Sieber, R. 1993. Cholesterol removal from animal food - Can it be justified'? CH-3097 Fed. Dairy Res. Inst. Liebefeld, Switzerland. pp. 375-387.

Shim, S. Y., J. Ahn and H. S. Kwak. 2003. Functional properties of cholesterol-removed whipping cream treated by $\beta$-cyclodextrin. J. Dairy Sci. 86:2767-2772.

Szejtli, J. 1982. Chemistry and separation of cyclodextrins. In: (Ed. J. Szjetli) Cyclodextrins and their inclusion complexes. Akademiai Kiado, Budapest, Hungry. pp. 17-43.

Shim, S. Y., J. Ahn and H. S. Kwak. 2004. Functional properties of cholesterol-removed compound whipping cream by palm oil. Asian-Aust. J. Anim. Sci. 17:857-862.

Whistler, R. and R. Daniel. 1990. Function of polysaccharide. In: Food additives, Dekker, New York, NY, USA. pp. 399-406.

Yen, G. C. and L. T. Tsui. 1995. Cholesterol removal from lardmixture with $\beta$-cyclodextrin. J. Food Sci. 60:561-564.