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Effects of Chromium Propionate Supplementation on Growth Performance, Serum Traits and Immune Response in Weaned Pigs
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 Title & Authors
Effects of Chromium Propionate Supplementation on Growth Performance, Serum Traits and Immune Response in Weaned Pigs
Lien, T.-F.; Yang, K.-H.; Lin, K.-J.;
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 Abstract
This study investigated the effects of chromium propionate on growth performance, serum traits and immune response in weaned pigs. Twenty-four 4 wk-old crossbred weanling pigs (initial body weight about 9.520.48 kg) were randomly allotted into one of two groups, a control group (basal diet), chromium propionate group (diet supplemented with 200 (ppb) of chromium propionate). This experiment was conducted over nine weeks. Escherichia coli lipopolysaccharide (LPS) 100 BW was used as the stress-inducing agent in the middle (4 wks) and final (8 wks) periods. The experimental results indicated that chromium propionate had no effect on growth performance (p>0.05). Chromium propionate supplementation reduced the percentage of LDL+VLDL (low and very low-density lipoprotein) and increased HDL (high-density lipoprotein), but did not affect other serum traits. Pigs supplemented with chromium propionate had higher antibody titers specific for sheep red blood cells (SRBC) and serum total globulin relative to the control during the final period (p<0.05). A challenge with LPS increased white blood cells in the chromium propionate group in both experimental periods (p<0.05). The chromium propionate group exhibited higher IgG and -globulin than the control during the middle experimental period (p<0.05). Moreover, the PHA (phytohemagglutinin) challenge result in the chromium propionate group was better than the control group (p=0.056). Greater neutrophil activity was displayed than in the control (p<0.05). This suggests that chromium propionate supplementation benefited the weaned pigs in lipoprotein and immune response.
 Keywords
Chromium Propionate;Serum Traits;Immune Response;Pigs;
 Language
English
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 References
1.
Amoikon, E. K., J. M. Fernandez, L. L. Southern, Jr. D. L. Thompson, T. L. Ward and B. M. Olcott. 1995. Effect of chromium tripicolinate on growth glucose tolerance, insulin sensitivity, plasma metabolites, and growth hormone in pigs. J. Anim. Sci. 73:1123-1130.

2.
Anderson, R. A. 1986. Chromium metabolism and its role in disease processes in man. Clin. Physiol. Biochem. 4:31-41.

3.
Anderson, R. A., M. M. Polansky, N. A. Bryden, S. J. Bhathena and J. J.Canary. 1987. Effects of supplemental chromium on patients with symptoms of reactive hypoglycemia. Metabolism. 38:351-355.

4.
Anderson, R. A., M. P. Polansky, N. A. Bryden and J. J. Canary. 1991. Supplemental chromium effects on glucose, insulin, glucagon and urinary chromium losses in subjects consuming controlled low-chromium diets. Am. J. Clin. Nutr. 54:909-916.

5.
Blecha, F., S. L. Boyles and J. G. Riley. 1984. Shipping suppresses lymphocyte blastogenic responses in Angus and Brahman${\times}$Angus feeder calves. J. Anim. Sci. 59:576-583.

6.
Burton, J. L., B. A. Mallard and D. N. Mowat. 1993. Effect of supplement of chromium on immune response of periparturient and early lactation of dairy cows. J. Anim. Sci. 71:1532-1539.

7.
Chang, X. and D. N. Mowat. 1992. Supplemental chromium for stressed and growing feeder calves. J. Anim. Sci. 70:559-565.

8.
Chang, X., B. A. Mallard and D. N. Mowat. 1996. Effects of chromium on health status, blood neutrophil phagocytosis and in vitri lymphocyte blastogenesis of dairy cows. Vet. Immunol. Immunopathol. 52:37-52.

9.
Coa, J., K. Li, X. Lu and Y. Zhao. 2004. Effects of florfenicol and chromium (III) on humoral immune response in chicks. Asian-Aust. J. Anim. Sci. 17:366-370.

10.
Evans, G. W. 1989. The effect of chromium picolinate on insulin controlled parameters in humans. Internat. J. Biophys. Med. Res. 11:163-180.

11.
Kegley, E. B. and J. W. Spears. 1995. Immune response, glucose metabolism, and performance of stressed feeder calves fed inorganic or organic chromium. J. Anim. Sci. 73:2721-2726.

12.
Kegley, E. B., J. W. Spears and T. T. Brown. 1996. Immune response and disease resistance of calves fed chromium nucotinic acid complex or chromium chloride. J. Dairy Sci. 79:1278-1283.

13.
Lee, D. N., C. F. Weng, H. T. Yen, T. F. Shen and B. J. Chen. 2000. Effects of chromium supplementation and lipopolysacchride injection on physiological response of weanling pigs. Asian-Aust. J. Anim. Sci. 13:528-534.

14.
Leslie, H. and C. H. Frank. 1989. Practical Immunology. Third ed. p. 23.

15.
Lien, T. F., C. P. Wu, J. J. Lu and R. G. R. Chou. 1996. Effects of supplemental chromium picolinate on growth performances, serum traits and carcass characteristics of pigs. J. Chinese Society of Animal Science 25(3):225-262.

16.
Lien, T. F., C. P. Wu, P. H. Lin, B. J. Wang, J. J. Lu and T. Y. Shiao. 1998. Effect of different protein and limiting amino acid levels coupled with a supplement of chromium picolinate on lipid metabolism and carcass characteristics of pigs. Anim. Sci. 67:601-607.

17.
Lien, T. F., Y. M. Horng and K. H. Yang. 1999a. Growth performance, serum characteristics, carcass traits and lipid metabolism of broilers as affected by supplement of chromium picolinate. Br. Poult. Sci. 40:357-363.

18.
Lien, T. F. and D. F. Jan. 1999b. The lipogenic capacity of hepatocytes and lipolytic rate of adipocytes in Tsaiya ducks during growing and laying periods. Asian-Aust. J. Anim. Sci. 12(8):1258-1262.

19.
Lien, T. F., C. P. Wu, B. J. Wang, M. S. Shiao, T. Y. Shiao, B. H. Lin and C. Y. Hu. 2001. Effect of supplemental levels of chromium picolinate on the growth performance, serum traits, carcass characteristics and lipid metabolism of growingfinishing pigs. Anim. Sci. 72:289-296.

20.
McCarty, M. F. 1991. The case for supplemental chromium and a survey of clinical studies with chromium picolinate. J. Apply Nutr. 43:58-66.

21.
Mertz, W. 1993. Chromium in Human Nutrition: A Review. J. Nutr. 123:626-633.

22.
Moonsie-Shageer, S. and D. N. Mowat. 1993. Effect of level of supplemental chromium on performance, serum constituents, and immune status of stressed feeder calves. J. Anim. Sci. 71:232-238.

23.
Morris, B. W., A. Blumsohn, S. M. Neil and T. A. Gray. 1992. The trace element chromium-a role in glucose homeostasis. Am. J. Clin. Nutr. 55:989-991.

24.
Morrow-Tesch, J. and G. Andersson. 1994. Immunological and hematological characterizations of the wasting pig syndrome. J. Anim. Sci. 72:976-983.

25.
Mowat, D. N., X. Chang and W. Z. Yang. 1993. Chelated chromium for stressed feeder calves. Can. J. Anim. Sci. 73:49-55.

26.
National Research Council. 1989. Recommended Dietary Allowances. National Academy Press. Washington, DC.

27.
Norimatus, M., T. Ono, A. Aoki, K. Ohishi, T. Takahashi, G. Watanabe, K. Taya, S. Sasamoto and Y. Tamura. 1995. Lipopolysaccharide-induced apoptosis in swine lymphocytes in vivo. Infect. Immun. 63:1122-1126.

28.
Ohba, H., Y. Suzuki and H. Ohba. 1986. Enhancement of ribonucleic acid synthesis by chromium (III)-bound chromatin. J. Inorg. Biochem. 27:179-188.

29.
Okada, S., H. Tsukada and H. Ohba. 1984. Enhancement of nucleo RNA synthesis by chromium (III) in regenerating rat liver. J. Inorg. Biochem. 21:113-119.

30.
Page, T. G., L. L. Southern, T. L. Ward and Jr. D. L. Thompson. 1993. Effect of chromium picolinate on growth and serum and carcass traits of growing-finishing pigs. J. Anim. Sci. 71:656-662.

31.
Press, R. I., J. Geller and G. W. Evans. 1990. The effect of chromium picolinate on serum cholesterol and apolipoprotein fractions in human subjects. The Western J. Medic. 152:41-45.

32.
Richardson, R. P., C. D. Rhyne, Y. Fong, D. G. Hesse, K. J. Tracey, M. A. Marano, S. F. Lowry, A. C. Antonacci and S. E. Calvano. 1989. Peripheral blood leukocyte kinetics following in vivo lipopolysaccharide (LPS) administration to normal human sunjects. Ann. Surg. 124:239-245

33.
Rosebrough, R. W. and N. C. Steele. 1981. Effects of supplemental dietary chromium or nicotinic acid on carbohydrate metabolism during basal, starvation, and refeeding periods in poults. Poult. Sci. 60:407-417.

34.
Statistical Analysis System Institute. 1990. SAS/STAT User's guide, Version6.06, 4th ed. Cary, NC.

35.
Van de Ligt, J. L. G., M. D. lindemann, R. J. Harmon, H. J. Monegue and G. L. Ctomwell. 2002a. Effect of chromium tripicolinate supplementation on porcine immune response during the postweaning period. J. Anim. Sci. 80:449-455.

36.
Van de Ligt, J. L. G., M. D. lindemann, R. J. Harmon, H. J. Monegue and G. L. Ctomwell. 2002b. Effect of chromium tripicolinate supplementation on porcine immune response during the periparturient and neonatal period. J. Anim. Sci. 80:456-466.

37.
Van Heugten, E. and J. W. Spears. 1997. Immune response and growth of stressed weaning pigs fed diets supplemented with organic or inorganic forms of chromium. J. Anim. Sci. 75:409-416.

38.
Walker, M. 1993. Chromium: the essential mineral. Health Foods Business 5:51-52.

39.
Ward, T. L., L. F. Berrio, L. L. Southern, J. M. Fernandez and Jr. D. L. Thompson. 1994. In vivo and in vitro evaluation of chromium tripicolinate on insulin binding in pig liver cell plasma membranes. FASEB J. 8:A194.