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Study of the Application of Fructooligosaccharides in Piglets
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 Title & Authors
Study of the Application of Fructooligosaccharides in Piglets
Xu, Chuanlai; Chen, Xudong; Ji, Cheng; Ma, Qiugang; Hao, Kai;
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 Abstract
In this study, 90 crossbred weaned pigs(DurocLandraceLarge White)weighing - 7.860.06 kg each were randomly allotted to one of three dietary treatments. Control pigs were a fed corn-soybean meal diet with no additives. The two treatment groups were fed the basal diet supplemented either with 75 mg/kg Aureomycin or 0.4% fructooligosaccharides (FOS) in order to study the effects on performance, serological indices, and enteric morphology in addition to examining the content of volatile fatty acids in intestinal digesta. The results indicate that the diets containing FOS and antibiotics had a significant effect on feed conversion ratios (FCR) and diarrhea incidence, as well as increasing the concentrations of isobutyric and butyric acid and total VFAs in the caecum, and acetic acid, isovaleric acid, and total VFAs in feces. Supplementation with FOS also resulted in significantly longer mucosal villi height and a higher percentage of goblet cells compared with the control. No difference was found in crypt depth among the three treatments. While serum glucose levels were significantly higher following FOS supplement, differences in serum total protein, albumin, globulin, and urea nitrogen levels were not significant.
 Keywords
FOS;Growing Performance;Enteric Morphology;Serum;VFAs;Piglet;
 Language
English
 Cited by
 References
1.
Ammerman, E., C. Quarles and P. V. Twining, Jr. 1988. Broiler response to the addition of dietary fructooligosaccharides. Poult. Sci. 67(Suppl. 1):67(Abstr.).

2.
Bailey, J. S., L. C. Blackenship and N. A. Cox. 1991. Effect of fructooligosaccharides on salmonella colonization of the chicken intestine. Poult. Sci. 70:2433-2438.

3.
Bergman, E. N. 1990. Energy contributions of volatile fatty acids from the gastrointestinal tract in various species. Physiological Reviews.70:567-590.

4.
Cummings, J. H., G. T. Macfarlane and H. N. Englyst. 2001. Prebiotic digestion and fermentation. J. Clin Nutr. Am. 73:415-420.

5.
Friend, D. W., J. W. G. Nicholson and H. M. Cunningham. 1964. Volatile fatty acid and lactic acid content of pig blood. Can. J. Anim. Sci. 44:303-309.

6.
Fukuyasu, T., T. Oshida and K. Ashida. 1987. Effect of oligosaccharides on growth of piglets and on bacterial flora, putrefactive substances and volatile fatty acids in their feces. Bull. Anim. Hyg. 26:15-22.

7.
Gibson, G. R. and M. B. Roberfroid. 1995. Dietary modulation of the human colonic microbiota: Introducing the concept of prebiotics. J. Nutr. 125:1401-1412.

8.
Hidaka, H., T. Eida, T. Takizawa, T. Tokunaga and Y. Tashiro. 1986. Effects of fructooligosaccharides on intestinal flora and human health. Bifidobact. Microflora. 5:37-50.

9.
Houdijk, G. M., M. W. Bosch and H. J. Verstegen. 1998. Effects of dietary oligosaccharides on the peformance and faecal characteristics of young growing pigs. Anim. Feed Sci. Technol. 71:35-48.

10.
Howard, M. D., D. T. Gordon, L. W. Pace, K. A. Garleb and M. S. Kerley. 1995. Effects of dietary supplementation with fructooligosaccharides on colonic microbiota populations and epithelial cell proliferation in neonatal pigs. J. Ped. Gastroenter. Nutr. 21:297-303. crossref(new window)

11.
Imoto, S. and S. Namioka. 1978. VFA production in the pig large intestine. J. Anim. Sci. 47:467-478.

12.
Lee, J., A. Ametani, A. Enomoto, Y. Sato, H. Motoshima, F. Ike and S. Kaminogawa. 1993. Screening for the immunopotentiating activity of food microorganisms and enhancement of the immune response by Bifidobacterium adolescentis M101-4. Biosci. Biotechnol. Biochem. 57:2127-2132.

13.
Mathew, A. G., S. E. Chattin, C. M. Robbins and D. A. Golden. 1998. Effects of a direct-fed yeast culture on enteric microbial populations, fermentation acids, and performance of weanling pigs. J. Anim. Sci. 76:2138-2145.

14.
NRC, National Research Council 1998. Research Priorities for Airborne Particulate Matter, National Academy Press, Washington, DC.

15.
Ohta, A., S. Baba, T. Takizawa and T. Adachi. 1994. Effects of fructooligosaccharides on the absorption of magnesium in the magnesium-deficient rat model. J. Nutr. Sci. Vitaminol. 40:171-180.

16.
Orban, J. I., J. A. Patterson, A. L. Sutton and G. N. Richards. 1993. Effect of sucrose thermal oligosaccharide caramel on growth and intestinal microflora of broiler chickens. Poult. Sci. 72(Suppl. 1):132(Abstr.).

17.
Orban, J. I., J. A. Patterson, A. L. Sutton and G. N. Richards. 1994. Effect of sucrose thermal oligosaccharide caramel (STOC) on growth performance and intestinal microbial populations in growing pigs. In: Proc. VIth Int. Symp. on Digestive Physiology in Pigs. EAAP Publ. 80:280. Bad Doberan, Germany.

18.
Orban, J. I., J. A. Patterson, A. L. Sutton, O. Adeola and G. N. Richards. 1995a. Growth performance and intestinal microbial populations in White Pekin ducks fed diets containing sucrose thermal oligosaccharide caramel. Poult. Sci. 74(Suppl. 1): 209(Abstr.).

19.
Orban, J. I., J. A. Patterson, A. L. Sutton and G. N. Richards. 1995b. Influence of sucrose thermal oligosaccharide caramel and vitamin-mineral level on growth and changes in intestinal microbial populations in broilers from day-old to four weeks of age. Poult. Sci. 74 (Suppl. 1):209(Abstr.).

20.
Patterson, J. A., A. L. Sutton, J. I. Orban and G. N. Richards. 1993. Effect of kestoses from thermolysis of sucrose on growth of intestinal bacteria, performance and intestinal microflora of broiler chickens. Poult. Sci. 72(Suppl. 1):132(Abstr.).

21.
Quigly, M. E., G. J. Hudson, H. N. Englyst. 1999. Determination of resistant short-chain carbohydrates (non-digestible oligosaccharides) using gas-liquid chromatography. Food Chem. 65:381-390.

22.
Roediger, W. E. W. 1980. Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man. Gut. 21:793-798.

23.
SAS. 1987. SAS User’s Guide: Statistics (Version 6.01 Ed.). SAS Inst. Inc., Cary, NC.

24.
Tellez, G., C. E. Dean, D. E. Corrier, J. R. Deloach, L. Jaeger and B. M. Hargis. 1993. Effect of dietary lactose on cecal morphology, pH, organic acids and Salmonella enteritidis organ invasion in leghorn chicks. Poult. Sci. 72:636-642.

25.
Tokunaga, T., T. Oku and N. Hosoya. 1989. Utilization and excretion of a new sweetener, fructooligosaccharide (Neosugar), in rats. J. Nutr. 119:553-559.

26.
Tsukahara, T., Y. Iwasaki, K. Nakayama and K. Ushida. 2003. Stimulation of butyrate production in the large intestine of weaning piglets by dietary fructooligosaccharides and its influence on the histological variables of the large intestinal mucosa. J. Nutr. Sci. Vitaminol (Tokyo). 49(6):414-421.

27.
Waldroup, A. L., J. T. Skinner, R. E. Hierholzer and P. W. Waldroup. 1993. An evaluation of fructooligosaccharide in diets for broiler chickens and effects on Salmonella contamination of carcasses. Poult. Sci. 72:643-650.

28.
Yoshioka, M., Y. Shimomura and M. Suzuki. 1994. Dietary polydextrose affects the large intestine in rats. J. Nutr. 124:539-547.