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Effects of Dietary Supplemented Inorganic and Organic Selenium on Antioxidant Defense Systems in the Intestine, Serum, Liver and Muscle of Korean Native Goats
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 Title & Authors
Effects of Dietary Supplemented Inorganic and Organic Selenium on Antioxidant Defense Systems in the Intestine, Serum, Liver and Muscle of Korean Native Goats
Chung, J.Y.; Kim, J.H.; Ko, Y.H.; Jang, I.S.;
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The present study was designed to assess whether dietary inorganic and organic selenium (Se) could affect antioxidant enzymes, including superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and glutathione-S-transferase (GST), and the level of malondialdehyde (MDA), a marker of lipid peroxidation, in the intestine, serum, liver, and gastrocnemius muscle of Korean native goats. A total of eighteen Korean native goats was allotted into three dietary groups, consisting of basal diet (CON), or basal diet with either 0.25 ppm inorganic (IOSEL) or 0.25 ppm organic Se (ORSEL), and fed the corresponding diets for 5 wks. Growth performance, including body weight and total gain, and blood biochemical profiles, including GSH-Px, were not significantly different between the three dietary groups. Also, the specific activities of SOD, GSH-Px, and GST, and the level of MDA in the intestinal mucosa and liver from goats were not substantially affected by either inorganic Se or organic Se. However, goats fed the diet containing organic Se showed a significant increase in GSH-Px and GST activities in the gastrocnemius muscle compared with those fed the basal diet. In conclusion, increased muscle GSH-Px and GST activities suggest that dietary organic Se may affect, at least in part, the antioxidant defense system in muscle of Korean native goats under the conditions of our feeding regimen.
Inorganic Se;Organic Se;Korean Native Goats;Antioxidant Enzymes;SOD;GSH-Px;GST;MDA;
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