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Association between PCR-RFLP Polymorphisms of Five Gene Loci and Milk Traits in Chinese Holstein
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 Title & Authors
Association between PCR-RFLP Polymorphisms of Five Gene Loci and Milk Traits in Chinese Holstein
Zhang, R.F.; Chen, H.; Lei, C.Z.; Fang, X.T.; Zhang, Y.D.; Hu, S.R.; Su, L.H.;
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The objective of this study was to assess the association of polymorphisms in -cn, -lg, -lg 5′ flanking region, CSN1S2, and IGFBP-3 genes with milk production traits and mastitis-related traits in Chinese Holstein. Traits analyzed were 305 day standard milk yield, protein percentage, fat percentage, the ratio of fat percentage and protein percentage, pre-somatic cell count, somatic cell count, and somatic cell score, respectively. CSN1S2 locus was uninformative because only one genotype BB was found in Chinese Holstein. Allele frequencies of A and B in IGFBP-3 gene were 0.5738 and 0.4262 in Chinese Holstein population, which was different from reported Qinchuan cattle population. The genotypes of animals at IGFBP-3 locus significantly affected 305 day standard milk yield, protein percentage, and somatic cell score. The -lg genotypes had a significant effect on protein percentage and the ratio of fat percentage and protein percentage. Polymorphism in -lg 5′ flanking region was associated with 305 day standard milk yield, protein percentage, fat percentage, pre-somatic cell count, and somatic cell count. No significant associations of the polymorphism in -cn gene were observed for any trait.
Chinese Holstein;-lg;-cn;IGFBP-3;Milk Traits;
 Cited by
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