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Effects of Nanocalcium Supplemented Milk on Bone Calcium Metabolism in Ovariectomized Rats
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 Title & Authors
Effects of Nanocalcium Supplemented Milk on Bone Calcium Metabolism in Ovariectomized Rats
Park, H.S.; Jeon, B.J.; Ahn, J.; Kwak, H.S.;
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 Abstract
This study examined effects of calcium supplemented milk on bone loss in ovariectomized rats. Twenty four Sprague-Dawley female rats, 7 weeks-old, were divided into 4 groups, ovariectomized and fed diets containing: 1) control, no Ca supplemented milk, 2) ovx 1, Ca carbonate supplemented milk, 3) ovx 2, ionized Ca supplemented milk, and 4) ovx 3, nano Ca supplemented milk. All rats were fed 1 ml of milk containing 20 mg supplemented Ca. After 18 wk feeding, body weight gain and food efficiency ratio were significantly different between ovx 1 and ovx 3. Serum concentration of calcium and phosphorus were not different among groups. However, there was a significant difference in calcium content of dry femoral weight in ovx 3 compared with the control and ovx 2. In addition, femoral bone mineral density () was significantly greater in ovx 3 than in other groups (p<0.05). The ovx 3 group showed the highest stiffness (N/mm), maximum energy (N) in femur and trabecular bone area (%). The present study indicated that nano Ca supplementation in milk may be an effective way to enhance bone calcium metabolism for ovariectomized rats.
 Keywords
Nanocalcium;Bone Ca Metabolism;Milk;Ovariectomized Rat;
 Language
English
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 References
1.
Arnaud, C. D. and S. Z. Sanchez. 1990. The role of calcium in osteoporosis. Annu. Rev. Nutr. 10:397-414. crossref(new window)

2.
Asawa, Y., N. Amizuka, K. Hara, M. Kobayashi, M. Aita, M. Li, S. Kenmotsu, K. Oda, Y. Akiyama and H. Ozawa. 2004. Histochemical evaluation for the biological effect of menatetrenone on metaphyseal trabeculae of ovariectomized rats. Bone 35:870-880. crossref(new window)

3.
Bell, G. H., D. P. Cuthbertson and J. Orr. 1941. Strength and size of bone in relation to calcium intake. J. Physiol. 100:299-317.

4.
Chen, K. L., M. H. Chang, S. M. Tsay, H. Y. Hurng and P. W. S. Chiou. 2006. Effects of caponization on bone characeristics and histological structure in chickens. Asian-Aust. J. Anim. Sci. 19:245-251.

5.
Christiansen, C. 1992. Prevention and treatment of osteoporosis: A review of current modalities. Bone 13: S35-S39. crossref(new window)

6.
Dawson-Hughes, B. 1991. Calcium supplementation and bone loss: A review of controlled clinical trials. Am. J. Clin. Nutr. 54:274S-280S.

7.
Gallagher, J. C. 1993. Pathophysiology of osteoporosis. Semin. Nephrpl. 12:109-115.

8.
Hirasawa, T. N., N. Omi and I. Ezawa. 2001. Effect of 1$\alpha$- hydroxyvitamin D and egg-shell calcium on bone metabolism in ovariectomized osteoporotic model rats. J. Bone Miner. Metab. 19:84-88. crossref(new window)

9.
Ishida, H., T. Uesugi, K. Hirai, T. Toda, H. Nukaya, K. Yokotsuka and K. Tsuji. 1998. Preventive effects of the plant isoflavones, daidzin and genistin on bone mineral density in estrogenand/ or dietary calcium-deficient rats. Bone 16:149-156.

10.
Kansal, V. K. and S. Chaudhary. 1982. Biological availability of calcium, phosphorus and magnesium from dairy products. Milchwissenschaft 37:261-263.

11.
Li, L. L., Z. P. Hou, Y. L. Yin, Y. H. Liu, D. X. Hou, B. Zhang, G. Y. Wu, S. W. Kim, M. Z. Fan, C. B. Yang, X. F. Kong, Z. R. Tang, H. Z. Peng, D. Deng, Z. Y. Deng, M. Y. Xie, H. Xiong, P. Kang and S. X. Wang. 2007. Intramuscular administration of zinc metallothionein to preslaughter stressed pigs improves anti-oxidative status and pork quality. Asian-Aust. J. Anim. Sci. 20:761-767.

12.
Mortenson, L. and P. Charles. 1996. Bioavailability of calcium supplements and the effect of vitamin D. Am. J. Clin. Nutr. 17:1663-1670.

13.
Nordin, B. E. C., A. G. Need, M. Horowiz, H. A. Morris, T. C. Durbridge and D. B. Cleghorn. 1991. Ostroporosis and calcium. Aust. NZ J. Med. 21:275-279.

14.
Poneros-Schneier, A. G. and J. W. Erdman Jr. 1982. Bioavailability of calcium from sesame seeds. Almond powder, whole wheat bread, spinach and nonfat dry milk in rats. J. Food Sci. 54:150-153. crossref(new window)

15.
Rader, J. I., D. J. Baylink, M. R. Hughers, E. F. Safilian and M. R. Haussler. 1979. Calcium and phosphorus deficiency in rats: Effects on PTH and 1,25 dihydroxyvitamin D3. Am. J. Physiol. 236:E118-E122.

16.
SAS. 1985. User's Guide: Statistics, Version 5 Edition, SAS Institute Inc., Cary, NC, USA.

17.
Shen, V., R. R. Birchman, R. Xu, R. Lindsay and D. W. Dempster. 1995. Short-term changes in histomorphometric and biochemical turnover markers and bone mineral density in estrogen- and/or dietary calcium-deficient rats. Bone 16:149-156.

18.
Shen, V., D. W. Demster, R. Birchman, R. Xu and R. Lindsay. 1993. Loss of cancellous bone mass and connectivity in ovariectomized rats can be restored by combined treatment with PTH and estradiol. J. Clin. Invest. 91:2479-2487. crossref(new window)

19.
Sissons, H. A., G. J. Kelman and G. Marotti. 1984. Mechanisms of bone formation, mineralization, and enhanced resorption in calcium-deficient rats. Am. J. Physiol. 225:269-276.

20.
Tamaki, H., T. Akamine, N. Goshi, H. Kurata and T. Sakou. 1998. Effects of exercise raining and etidronate treatment on bone mineral density and trabecular bone in ovariectomized rats. Bone 23:147-153. crossref(new window)

21.
Thomas, M. L., D. J. Simmons, L. Kidder and M. Ibarra. 1991. Calcium metabolism and bone mineralization in female rats fed marginally sufficient in calcium: Effects of increased dietary calcium intake. Bone Miner. 12:1-14. crossref(new window)

22.
Toba, Y., M. Takada, M. Tanaka and S. Aoe. 1999. Comparison of the effects of milk components and calcium source on calcium bioavailability in growing male rats. Nutr. Res. 19:449-459. crossref(new window)

23.
Tsuchiya, H., I. Sekiguchi and T. Kuwata. 1993. Comparison of the effects of whey mineral complexes on bone metabolism in male growing rats. J. Nutr. Sci. Vitaminol. 39:473-487.

24.
Wong, N. P. and D. E. Lacroix. 1980. Biological availability of calcium in dairy products. Nutr. Rep. Int. 21: 673-680.

25.
Wong, K. M., L. Singer and R. H. Ophanug. 1980. Metabolic aspects of bone resorption in calcium-deficient lactating rats. Calcif. Tissue Int. 2:213-219.