Advanced SearchSearch Tips
Microencapsulation of Korean Mistletoe (Viscum album var. coloratum) Extract and Its Application into Milk
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Microencapsulation of Korean Mistletoe (Viscum album var. coloratum) Extract and Its Application into Milk
Kim, N.C.; Kim, J.B.; Kwak, H.S.;
  PDF(new window)
This study was designed to develop microencapsulated Korean mistletoe extract, to determine the stability in vitro and to examine its application in milk. Coating materials used were polyglycerol monostearate (PGMS) and medium-chain triacylglyderol (MCT). The highest efficiency of microencapsulation was 78.3% with 15:1:40 (w/w/v) as PGMS : mistletoe extract : distilled water and 66.1% with 15:1 (w/w) as MCT : mistletoe extract. The size of microcapsule was about 30.0 and with PGMS and MCT, respectively. When microcapsules of mistletoe extract were incubated in simulated gastric fluid at pH 2 for 60 min, 14.8 and 17.2% of lectin was released from capsules which were coated with PGMS and MCT, respectively. Comparatively, 83.2 and 87.3% of lectin was released in simulated intestinal fluid (pH 8) after 60 min incubation of capsules coated with PGMS and MCT, respectively. The subsequent study determined the changes of physicochemical and sensory characteristics of milk with fortification of the mistletoe extract microcapsules during 12 day storage. TBA value was significantly lower in microcapsule-added groups than in the uncapsulated mistletoe extract-added group during the storage. When 100 ppm microencapsulated mistletoe extract was added, the L-, a- and b- values and viscosity were not significantly different from those of the control. In addition, the release of lectin from mistletoe extract over 12 days was 8.3 and 9.5 mg/100 ml in milk containing microcapsules made by PGMS and MCT, respectively. All sensory attributes showed a significant difference in uncapsulated mistletoe extract-added milk compared with other groups. The present study indicated that microcapsules of Korean mistletoe extract could be applied to milk and microcapsules coated with PGMS were effectively released in a simulated intestinal environment.
Microencapsulation;Korean Mistletoe Extract;Polyglycerol Monostearate;Medium-chain Triacylglycerol;Milk;
 Cited by
Optimization of Microencapsulation of Inonotus obliquus Extract Powder by Response Surface Methodology and Its Application into Milk,Ahn, Sung-Il;Chang, Yoon-Hyuk;Kwak, Hea-Soo;

한국축산식품학회지, 2010. vol.30. 4, pp.661-668 crossref(new window)
Bersen'eva, E. A., A. A. Inanov, T. P. Sansonova, E. M. Chernova, and N. I. Oragvelidze. 1990. Microencapsulated aromatizers for tea. Pishchevaya Paomyshlennost, USSR 1:57-59.

Braun, S. D. and N. F. Olson. 1986. Encapsulation of proteins and peptides in milk fat. Encapsulation efficiency and temperature and freezing stability. J. Microencapsulation 3(2):115-126. crossref(new window)

Choi, H. J., J. Ahn, N. C. Kim and H. S. Kwak. 2006. The effects of microencapsulated chitooligosaccharide on physical and sensory properties of the milk. Asian-Aust. J. Anim. Sci. 19:1347-1353.

Franz, H. 1991. In: Advances in lectin research (Ed. H. Franz, Kichi Kasai, J. Kochaurek, S. Olsnes, L. M. Shannon). pp. 4:33-50. Verlag Gesundheit and Springer Verlag, Berlin.

Gabius, H. J., S. Gabius and S. S. Joshi. 1994. Form ill-defined to the immunomodulatory lectin: will there be a reason for oncological of mistletoe: Planta Med. 60:2-7. crossref(new window)

Hajto, T., K. Hostanska, and H. J. Gabius. 1989. Modulatory potency of the $\beta$-galactosidase-specific lectin from mistletoe (lscador) on the host defense system in vivo in rabbits and patients. Cancer Res. 49:4803-4808.

Jackson, L. S. and K. Lee. 1991. Microencpasulated iron food fortification. J. Food Sci. 56:1047-1050. crossref(new window)

Kim, N. C., B. J. Jeon, J. Ahn and H. S. Kwak. 2006. In vitro study of microencapsulated isoflavone and $\beta$-galactosidase. J. Agric. Food Chem. 54:2582-2586. crossref(new window)

Kuttan, G. 1993. Tumoricidal activity of mouse peripheral macrophages treated with Viscum album extract. Immunol. Investig. 22:431-440. crossref(new window)

Kwaja, T. A., C. B. Dias and S. Pentecost. 1986. Recent studies on the anticancer activities of mistletoe (Viscum album) and its alkaloids. Oncology 43:42-50. crossref(new window)

Kwak, H. S., M. R. Ihm and J. Ahn. 2001. Microencapsulation of $\beta$-galactosidase with fatty acid esters. J. Dairy Sci. 84:1576-1582. crossref(new window)

Kwak, H. S., K. M. Yang and J. Ahn. 2003. Microencpasulated iron for milk fortification. J. Agric. Food Chem. 51:7770-7774. crossref(new window)

Magee, E. L. Jr. and N. F. Olson. 1981a. Microencapsulation of cheese ripening systems: Formation of microcapsules. J. Dairy Sci. 64:600-610. crossref(new window)

Magee, E. L. Jr. and N. F. Olson. 1981b. Microencapsulation of cheese ripening systems: Stability of microcapsules. J. Dairy Sci. 64:611-615. crossref(new window)

Lee, J. B., J. Ahn, J. H. Lee and H. S. Kwak. 2003. The microencapsulated ascorbic acid released in vitro and its effect on iron bioavailability. Arch. Pharm. Res. 26:874-879. crossref(new window)

Park, C. H., D. W. Lee, T. B. Kang, K. H. Lee, T. J. Yoon, J. B. Kim, M. S. Do and S. K. Song. 2001. cDNA cloning and sequence analysis of the lectin genes of the Korean mistletoe (Viscum album coloratum). Mol. Cells 12:215-220.

SAS. 1985. User's Guide: Statistics, Version 5 Edition. SAS Institute, Inc., Cary, NC

Stoeva, S., M. Franz, R. Wacker, R. Krauspenhaar, E. Guthohrlein, A. Mikhailov, C. Betzel and W. Voelter. 2001. Promary structure, isoforms, and molecular modeling of a chitinbinding mistletoe lectin. Arch. Biochem. Biophys. 392:23-31. crossref(new window)

Yoon, T. J., Y. C. Yoo, O. B. Choi, M. S. Do, T. B. Kang, S. W. Lee, I. Azuma and J. B. Kim. 1995. Inhibitory effect of Korean mistletoe (Viscum album coloratum) extract on tumor angiogenesis and metastasis of haematogenous and nonhaematogenous tumor cells in mice. Cancer Lett. 97:83-91. crossref(new window)

Yoon, T. J., Y. C. Yoo, T. B. Kang, E. Her, S. H. Kim, K. Kim, I. Azuma and J. B. Kim. 2001. Cellular and humoral adjuvant activity of lectins isolated from Korean mistletoe (Viscum album coloratum). Int. Immunopharmacol. 1:881-889. crossref(new window)

Yoon, T. J., Y. C. Yoo, T. B. Kang, K. Shimazaki, S. K. Song, K. H. Lee, S. H. Kim, C. H. Park, I. Azuma and J. B. Kim. 1999. Lectins isolated from Korean mistletoe (Viscum album coloratum) induce apoptosis in tumor cells. Cancer Lett. 136:33-40. crossref(new window)