JOURNAL BROWSE
Search
Advanced SearchSearch Tips
Supplementation of Holstein Cows with Low Doses of Bovine Somatotropin (bST) Prepartum and Postpartum Affects Physiological Adaptations and Milk Production
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Supplementation of Holstein Cows with Low Doses of Bovine Somatotropin (bST) Prepartum and Postpartum Affects Physiological Adaptations and Milk Production
Liboni, M.; Gulay, M.S.; Hayen, M.J.; Belloso, T.I.; Head, H.H.;
  PDF(new window)
 Abstract
Major objectives were to evaluate effects of three schemes of bST-supplementation of Holstein cows (142.8 mg/14 d, POSILAC) during the prepartum and/or postpartum periods through 63 d () of lactation. Measures evaluated the potential of treatments to improve body weight (BW) and body condition score (BCS), provoke changes in plasma concentrations of somatotropin (ST) and IGF-I, and improve milk yield, milk composition (percentages of protein and fat, and somatic cell counts), and several calving variables. Multiparous Holstein cows were randomly assigned to a factorial arrangement of treatments (TRT) to give four groups (I = no bST, n = 26; II = bST postpartum, n = 25; III = bST prepartum, n = 27; IV = bST prepartum and postpartum, n = 25). During the prepartum period, cows in groups I and II were not supplemented but those in groups III and IV were supplemented every 2-wk beginning 21 d before expected calving date through calving. During the first 63 DIM only cows in groups II and IV were supplemented with bST. From 64 DIM through the end of lactation cows in all groups were supplemented with the full lactation dose of bST (500 mg/14 d). The BW and BCS were recorded weekly throughout the prepartum and postpartum periods and every 2-wk beyond 70 DIM. Blood samples were collected 3-times a week for analyses of ST and IGF-I. Milk yields were recorded daily though 150 DIM. Prepartum supplementation of bST did not affect BW or BCS, but mean concentrations of ST were increased 12.2% and were 15.5% greater at calving. Overall, mean concentration of IGF-I was not affected by treatment but concentrations were greater at 1 and 2 wk before calving in bST-supplemented cows. During the first 63 DIM the BW and BCS were not affected by treatment. Significant effects of bST-supplementation were detected on concentrations of ST, IGF-I and on milk yield compared to non-supplemented cows in group I. Postpartum concentrations of ST were greater in bST-supplemented cows (TRT II and IV; +41.9 and 54.6%). However, concentrations of IGF-I were greater only in cows in group IV (+25.9%) during the postpartum period. Overall, the three bST-supplemented groups had greater actual milk yield than the control group (I) during the first 63 and 150 DIM. The actual milk yields during 63 and 150 DIM were 6.5 and 4.6 kg/d greater for cows in group IV than cows in group I and the 305-d ME milk yield also was 15.6% greater. No adverse effects of TRT were observed on calf birth weight, colostrum immunoglobulins, ease of calving or other measures evaluated.
 Keywords
bST;Holstein Cows;Hormones;Milk Production;Transition Period;
 Language
English
 Cited by
 References
1.
Abribat, T., H. Lapierre, P. Dubreuil, G. Pelletier, P. Gaudreau, P. Brazeau and D. Petitclerc. 1990. Insulin-like growth factor-I concentration in Holstein female cattle: variations with age, stage of lactation and growth-hormone-releasing factor administration. Domest. Anim. Endocrinol. 7:93-102. crossref(new window)

2.
Bachman, K. C., D. H. Wilfond, H. H. Head, C. J. Wilcox and M. Singh. 1992. Milk yields and hormone concentrations of Holstein cows in response to sometribove (somatotropin) treatment during the dry period. J. Dairy Sci. 75:1883-1890. crossref(new window)

3.
Bauman, D. E. 1999. Bovine somatotropin and lactation: from basic science to commercial application. Domest. Anim. Endocrinol. 17:101-116. crossref(new window)

4.
Bauman, D. E. and R. G. Vernon. 1993. Effects of exogenous bovine somatotropin on lactation. Annu. Rev. Nutr. 13:437-461. crossref(new window)

5.
Bell, A. W. 1995. Regulation of organic nutrient metabolism during transition from late pregnancy to early lactation. J. Anim. Sci. 73:2804-2819.

6.
Chilliard, Y. 1999. Metabolic adaptations and nutrient partitioning in the lactating animal (Ed. J. Martinet, L-M Houdebine and H. H. Head). Biology of Lactation. Paris:INRA. pp. 503-552.

7.
Daughaday, W. H., I. K. Mariz and S. L. Blethen. 1980. Inhibition of access of bound somatomedin to membrane receptor and immunobinding sites: a comparison of radioreceptor and radioimmunoassay of somatomedin in native and acid-ethanolextracted serum. J. Clin. Endocrinol. Metab. 51:781-788. crossref(new window)

8.
Edmonson, A. J., I. J. Lean, L. D. Weaver, T. Farver and G. Webster. 1989. A body condition scoring chart for Holstein dairy cows. J. Dairy Sci. 72:68-78. crossref(new window)

9.
Enright, W. J., J. F. Quirke, P. D. Gluckman, B. H. Breier, L. G. Kennedy, L. C. Hart, J. F. Roche, A. Coert and P. Allen. 1990. Effects of long-term administration of pituitary-derived bovine growth hormone and estradiol on growth in steers. J. Anim. Sci. 68:2345-2356.

10.
Eppard, P. J., J. J. Veenhuizen, W. J. Cole, P. G. ComensKeller, G. F. Hartnell, R. L. Hintz, L. Munyakazi, P. K. Olsson, R.H. Sorbet, T. C. White, C. A. Baile, R. J. Collier, J. P. Goff and R. L. Horst. 1996. Effect of bovine somatotropin administered to periparturient dairy cows on the incidence of metabolic disease. J. Dairy Sci. 79:2170-2181. crossref(new window)

11.
Fleenor, W. A. and G. H. Stott. 1980. Hydrometer test for estimation of immunoglobulin concentration in bovine colostrum. J. Dairy Sci. 63:973-977. crossref(new window)

12.
Garcia-Gavidia, A. N. 1998. Use of bST in management of growing heifers and transition cows to improve growth rates and milk production. PhD Dissertation. University of Florida, Gainesville, FL.

13.
Goff, D. 2002. Dairy chemistry and physics. Department of food science at University of Guelph home page. http://www.foodsci.uoguelph.ca/dairyedu/chem.html. Accessed on 05/11/2004.

14.
Goff, J. P. and R. L. Horst. 1997. Physiological changes at parturition and their relationship to metabolic disorders. J. Dairy Sci. 80:1260-1268 crossref(new window)

15.
Grummer, R. R. 1995. Impact of changes in organic nutrient metabolism on feeding the transition dairy cow. J. Anim. Sci. 73:2820-2833.

16.
Gulay, M. S., M. J. Hayen, L. C. Teixeira, C. J. Wilcox and H. H. Head. 2003. Responses of Holstein cows to a low dose of somatotropin (bST) prepartum and postpartum. J. Dairy Sci. 86:3195-3205. crossref(new window)

17.
Gulay, M. S., A. N. Garcia, M. J. Hayen, C. J. Wilcox and H. H. Head. 2004a. Responses of Holstein cows to different bovine somatotropin (bST) treatments during the transition period and early lactation. Asian-Aust J. Anim. Sci. 17:784-793.

18.
Gulay, M. S., M. J. Hayen, M. Liboni, T. I. Belloso, C. J. Wilcox and H. H. Head. 2004b. Low doses of bovine somatotropin during the transition period and early lactation improves milk yield, efficiency of production, and other physiological responses of Holstein cows. J. Dairy Sci. 87:948-960. crossref(new window)

19.
Gulay, M. S., M. Liboni, M. J. Hayen and H. H. Head. 2007. Supplementing Holstein cows with low doses of bovine somatotropin prepartum and postpartum reduces calvingrelated diseases. J. Dairy Sci. 90:5439-5445. crossref(new window)

20.
Kobayashi, Y., C. K. Boyd, C. J. Bracken, W. R. Lamberson, D. H. Keisler and M. C. Lucy. 1999. Reduced growth hormone receptor (GHR) messenger ribonucleic acid in liver of periparturient cattle is caused by a specific down-regulation of GHR 1A that is associated with decreased insulin-like growth factor I. Endocrinology. 140:3947-3954. crossref(new window)

21.
Littell, R. C., P. R. Henry and C. B. Ammerman. 1998. Statistical analysis of repeated measures data using SAS procedures. J. Anim. Sci. 76:1216-1231.

22.
Moallem, U., M. Kaim, Y. Folman and D. Sklan. 1997. Effect of calcium soaps of fatty acids and administration of somatotropin in early lactation on productive and reproductive performance of high producing dairy cows. J. Dairy Sci. 80:2127-2136. crossref(new window)

23.
Moallem, U., Y. Folman and D. Sklan. 2000. Effects of somatotropin and dietary calcium soaps of fatty acids in early lactation on milk production, dry matter intake, and energy balance of high-yielding dairy cows. J. Dairy Sci. 83:2085- 2094. crossref(new window)

24.
National Research Council. 2001. Nutrient Requirements of Dairy Cattle. 7th Rev. Ed. Natl. Acad. Press. Washington, DC.

25.
Santos, J. E. P., J. T. Huber, C. B. Theurer, C. B. Nussio, L. G. Nussio, M. Tarazon and R. O. Lima-Filho. 1999. Performance and nutrient digestibility by dairy cows treated with bovine somatotropin and fed diets with steam-flaked sorghum or steam-rolled corn during early lactation. J. Dairy Sci. 82:404- 411. crossref(new window)

26.
SAS OnlineDoc User Guide, Version 8. 2007. Cary, NC: SAS Institute Home Page. http://support.sas.com/rnd/app/da/stat.html.

27.
Simmons, C. R., W. G. Bergen, M. J. Vandehaar, D. J. Sprecher, C. J. Sniffen, E. P. Stanisiewski and H. A. Tucker. 1994. Protein and fat metabolism in cows given somavubove before parturition. J. Dairy Sci. 77:1835-1847. crossref(new window)

28.
Stanisiewski, E. P., L. F. Kraybill and J. W. Lauderdale. 1992. Milk yield, health and reproduction of dairy cows given somatotropin (somavubove) beginning early postpartum. J. Dairy Sci. 75:2149-2164. crossref(new window)

29.
Stelwagen, K., D. G. Grieve and B. W. McBride. 1991. Growth and subsequent lactation in primigravid Holstein heifers after prepartum bovine somatotropin treatment. J. Dairy Sci. 75:463-471. crossref(new window)