JOURNAL BROWSE
Search
Advanced SearchSearch Tips
Effect of Supplemental Selenomethionine on Growth Performance and Serum Antioxidant Status in Taihang Black Goats
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Effect of Supplemental Selenomethionine on Growth Performance and Serum Antioxidant Status in Taihang Black Goats
Yue, Wenbin; Zhang, Chunxiang; Shi, Liguang; Ren, Youshe; Jiang, Yusuo; Kleemann, D.O.;
  PDF(new window)
 Abstract
An experiment was conducted to evaluate the effect of different levels of supplemental selenomethionine (Se-Met) on growth performance and serum antioxidant status in Taihang Black goats. Fifty 16-week-old goats with an average body weight of 12.50.5 kg were randomly assigned to five treatments fed a basal diet (0.049 mg Se/kg DM) supplemented with 0 (control), 0.10, 0.30, 0.50 and 1.00 mg of Se/kg DM (form Se-Met) for 80 days. Average daily gain and feed efficiency were higher (p<0.05) in the groups supplemented with 0.30 to 0.50 mg Se/kg DM compared with the control group. However, Se-Met supplementation had no influence on average daily feed intake (p>0.05). Se-Met supplementation significantly increased (p<0.01) the activity of glutathione peroxidase enzymes (GSH-Px) and superoxide dismutase (SOD) in serum. The group supplemented with 0.50 mg Se/kg DM had the highest activity of GSH-Px compared with other groups (p<0.05). Serum SOD activity was higher (p<0.05) in goats supplemented with both 0.30 and 0.50 mg Se/kg DM than in control goats and goats supplemented with 1.00 mg Se/kg DM. Serum glutathione-S-transferase (GST) activity and malondialdehyde (MDA) concentration were significantly decreased (p<0.05) in goats supplemented with 0.30, 0.50 and 1.00 mg Se/kg DM compared with control values. These results indicated that Se-Met supplementation markedly improved the antioxidant status in goats. Blood Se concentration increased linearly (p<0.001) and quadratically (p<0.001) as the level of supplemental Se-Met increased. The concentration of Se in the control diet (0.049 mg Se/kg DM) did not satisfy the Se requirement in goats as indicated by reduced growth rate, feed efficiency, activities of GSH-Px and SOD in serum, and blood Se concentrations. In conclusion, it is recommended that 0.30 to 0.50 mg of Se/kg DM from Se-Met (total diet Se of 0.349 to 0.549 mg/kg DM) be supplied in the diet of Taihang Black goats to enhance growth performance and improve antioxidant status.
 Keywords
Taihang Black Goats;Selenomethionine;Growth Performance;Blood Se;Antioxidant Status;
 Language
English
 Cited by
1.
Effect of Organic Selenium (Sel-Plex) on Thermometabolism, Blood Chemical Composition and Weight Gain in Holstein Suckling Calves,;;;

Asian-Australasian Journal of Animal Sciences, 2009. vol.22. 7, pp.984-992 crossref(new window)
2.
Blood Haematology, Serum Thyroid Hormones and Glutathione Peroxidase Status in Kacang Goats Fed Inorganic Iodine and Selenium Supplemented Diets,;;;;;

Asian-Australasian Journal of Animal Sciences, 2013. vol.26. 11, pp.1577-1582 crossref(new window)
 References
1.
AOAC. 1990. Official Methods of Analysis, 15th edition. Association of Official Analytical Chemists, Arlington, VA

2.
Adkin, R. S. and R. C. Ewan. 1984. Effect selenium on performance, serum Selenium concentration and glutathione peroxidase activity. J. Anim. Sci. 58:346-350

3.
Arthur, J. R. 2000. The glutathione peroxidases. Cell. Mol. Life Sci. 57:1825-1835 crossref(new window)

4.
Arthur, J. R., P. C. Morrice, F. Nicol, S. E. Beddows, R. Boyd, J. D. Hayes and G. J. Beckett. 1987. The effects of selenium and copper deficiencies on glutathione-S-transferase and glutathione peroxidase in rat liver. Biochem. J. 248:539-544

5.
Beckett, G. J. and J. R. Arthur. 2005. Selenium and endocrine systems. J. Endocrin. 184:455-465 crossref(new window)

6.
Beck, P. A., T. J. Wistuba, M. E. Davis and S. A. Gunter. 2005. Effect of feeding supplemental organic or inorganic selenium to cow-calf pairs on Selenium status and immune responses of weaned beef calves. Prof. Anim. Sci. 21(2):114-120

7.
Cantor, A. H., M. L. Scott and T. Noguchi. 1975. Biological availability of selenium in feedstuffs and selenium compounds for prevention of exudative diathesis in chicks. J. Nutr. 105:96-105

8.
Cantor, A. H., P. D. Moorehead and M. A. Musser. 1982. Comparative effects of sodium selenite and selenomethionine upon nutrition muscular dystrophy, selenium-dependent glutathione peroxidase, and tissue selenium concentrations of turkey poults. Poult. Sci. 61:478-484

9.
Choct, M. and A. J. Naylor. 2004. The effect of dietary Selenium source and vitamin E levels on performance of male broilers. Asian-Aust. J. Anim. Sci. 17(7):1000-1006

10.
Commission Directive 2001/79/EC of 17 September 2001 amending Council Directive 87/153/EEC fixing guidelines for the assessment of additives in animal nutrition.7.3.2001 19-28

11.
Eglig, C. F., D. E. Hogue, W. H. Allaway and D. J. Hamm. 1967. Fate of selenium from selenite or selenomethionine with or without vitamin E in lambs. J. Nutr. 92:121-128

12.
Gao, J. H., S. Y. Qin and K. H. Huang. 2006. Effects of selenium enriched probiotics on antioxidative activities and immune functions in weanling piglets. Acta Nutrimenta Sinica, 28(2):132 (Abstract)

13.
G$\ddot{u}$nzler, W. A., H. Kremers and L. Floh$\acute{e}$. 1974. An improved coupled test procedure for glutathione peroxidase (EC 11119) in blood. Z. Klin.Chem. Klin Biochem.12:444-448

14.
Hassan, S., J. Hakkarainen, P. Lindberg and S. Sankari. 1988. Comparative effects of dietary sodium selenite on whole blood and plasma selenium and glutathione peroxidase in chick. Nutr. Rep. Int. 38:865-871

15.
Habig, W. H., M. J. Pabst and W. B. Jakoby. 1974. Glutathione -Stransferase: the first enzymatic step in mercapturic acid formation. J. Biolog. Chem. 249(22):7130-7139

16.
Hidiroglon, M., D. P. Heaney and K. J. Jenkins. 1968. Metabolism of inorganic selenium in rumen bacteria. Can. J. Physiol. Pharmacol. 46:229-232

17.
Hidiroglon, M. and K. J. Jenkins. 1973. Absorption of 75Seselenomethionine from the rumen of sheep. Can. J. Anim. Sci. 53:527-533 crossref(new window)

18.
Johnson, W. H., B. B. Norman and J. R. Dunbar. 1979. Selenium improves weight gain of beef calves. California Agric. 33(3):14-16

19.
Juniper, D. T., R. H. Phipps, A. K. Jones and G. Bertin. 2006. selenium supplementation of lactating dairy cows: effect on selenium concentration in blood, milk, urine and feces. J. Dairy. Sci. 89:3544-3551 crossref(new window)

20.
Juniper, D. T., R. H. Phipps, D. I. Givens, A. K. Jones. C. Green and G. Bertin. 2008. Tolerance of ruminant animals to high dose in-feed administration of a selenium-enriched yeast. J. Anim. Sci. 86(1):197-204 crossref(new window)

21.
Lawler, T. L., J. B. Taylor, J. W. Finley and J. S. Caton. 2004. Effect of supranutritional and organically bound selenium on performance, carcass characteristics, and selenium distribution in finishing beef steers. J. Anim. Sci. 82:1488-1493

22.
Mahan, D. C., T. R. Cline and B. Richert. 1999. Effect of dietary levels of selenium-enriched yeast and sodium selenite as selenium sources fed to grower-finisher pigs on resulting performance, tissue seleniums, serum glutathione peroxidase activity, carcass characterisitics, and lion quality. J. Anim. Sci. 77:2172-2179

23.
Maiorino, M., L. Floh$\acute{e}$, A. Roveri, P. Steinert, J. B. Wissing and F. Ursini. 1999. Selenium and reproduction. BioFactor. 10:251-256 crossref(new window)

24.
Masters, D. G., D. B. Purser, S. X. Yu, Z. S. Wang, R. Z. Yang, N. Liu, D. X. Lu, L. H. Wu, J. K. Ren and G. H. Li. 1993. Mineral nutrition of grazing sheep in northern china II. Selenium, copper, molybdenum, Iron and zinc in pasture, feed supplements and sheep. Asian-Aust. J. Anim. Sci. 6(1):107-114

25.
Mcdonald, J. W. 1975. Selenium responsive unthriftiness of young merino sheep in central victoria. Aust. Vet. J. 51(9):433-435 crossref(new window)

26.
McKenzie, R. C., T. S. Rafferty and G. J. Beckett. 1998. Selenium: an essential element for immune function. Trends. 19(8):342-345 crossref(new window)

27.
NRC. 1981. Nutrient requirements of goats. 5th revised edition. Washington DC: National Academy of Sciences, pp. 10-12

28.
Ortman, K. and B. Pehrson. 1997. Selenite and selenium yeast as feed supplements for dairy cows. J. Vet. Med. 4:373-380

29.
Paglia, D. E. and W. N. Valentine. 1967. Studies on the quantitative and qualitative characterization of erthrocyte glutathione peroxidase. J. Lab. Clin. Med. 70:158-169 crossref(new window)

30.
Paulson, D. G., C. A. Baumann and A. L. Pope. 1968. Metaboliam of $^{75}Se-selenite$, $^{75}Se-selenate$, $^{75}Se-selenomethionine$ and $^{35}Ssulfate$ by rumen microorganisms in vitro. J. Anim. Sci. 27:497-504

31.
Payne, R. L. and L. L.Southern. 2005. Comparison of Inorganic and Organic Selenium Sources for Broilers. Poult. Sci. 84(6):898-902

32.
Perry, T. W., W. M. Beeson, W. H. Smith and M.T. Mohler. 1976. Effect of supplemental selenium on performance and deposit of selenium in blood and hair of finishing beef cattle. J. Anim. Sci. 42:192-195

33.
Qin, S., J. Gao and K. Huang. 2007. Effects of different selenium sources on tissue selenium concentrations, blood GSH-Px activities and plasma interleukin levels in finishing lambs. Biol. Trace. Elem. Res. 116(1):91-102 crossref(new window)

34.
Robertson, J. B. and P. J. Van Soest. 1981. The detergent system of analysis and its application to human foods, Cornell Univ., Ithaca, New York

35.
Rotruck, J. T., A. L. Pope, H. E. Gather and A. B. Swanson. 1973. Selenium: Biochemical role as a component of glutathione peroxidase. Sci. 179:588-590 crossref(new window)

36.
Ryu, Y. C., M. S. Rhee, K. M. Lee and B. C. Kim. 2005. Effect of different levels of dietary supplemental selenium on performance, lipid oxidation, and color stability of broiler chicks. Poult. Sci. 84(5):809-815

37.
SAS. 2001. User's Guide: Statistics. Version 8.2, Cary, NC, USA

38.
Shilo, S., M. Pardo, M. A.Simon, S. Glibter and O. Tirosh. 2008. Selenium supplementation increase liver MnSOD expression: molecular mechanism for hepato-protection. J. Inorganic Biochem. 102:110-118 crossref(new window)

39.
Steen, A., T. Strom and A. Bernhoft. 2008. Organic selenium supplementation increased selenium concentrations in ewe and newborn lamb blood and in slaughter lamb meat compared to inorganic selenium supplementation. Acta. Vet. Scand. 50(1):7-13 crossref(new window)

40.
Sun, Y., W. Larry, W. Oberley and L. Ying. 1988. A simple method for clinical assay of superoxide dismutase. Clin. Chem. 24(3):497-500

41.
Tapiero, H., D. M. Townsend and K. D. Tew. 2003. The antioxidant role of selenium and seleno-compounds. Biomed. Pharma. 57:134-144 crossref(new window)

42.
Taylor, J. B. 2005. Time-dependent influence of supranutritional organically bound selenium on selenium accumulation in growing wether lambs. J. Anim. Sci. 83:1186-1193

43.
Tian, J. Z., M. S. Yun, W. S. Ju, H. F. Long, J. H. Kim, D. Y. Kil, J. S. Chang, S. B. Cho, Y. Y. Kim and In K. Han. 2006a. Effects of dietary selenium supplementation on growth performance, selenium retention in tissues and nutrient digestibility in growing-finishing pigs. Asian-Aust. J. Anim. Sci. 19(1):55-60

44.
Tian, J. Z., M. S. Yun, C. S. Kong, L. G. Piao, H. F. Long, J. H. Kim, J. H. Lee, J. S. Lim, C. H. Kim, Y. Y. Kim and In K. Han. 2006b. Effects of different products and levels of selenium on growth, nutrient digestibility and Selenium retention of growing-finishing pigs. Asian-Aust. J. Anim. Sci. 19(1):61-66

45.
Van Soest, P. J., J. B. Robertson and V. A. Lewis. 1991. Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition. J. Dairy. Sci. 74:3583-3597

46.
Wong, S. H., J. J. A. Knight, S. M. Hopfer, O. Zaharia, C. N. Leach and F. W. Sundermann. 1987. Lipoperoxides in plasma as measured by liquid-chromatographic separation of malondialdehyde-thiobarbituric acid addut. Clin.Chem. 33:214-219

47.
Wright, P. L. and M. C. Bell. 1966. Comparative metabolism of selenium and tellurium in sheep and swine. Am. J. Physiol. 211:6-10

48.
Yoon, I., T. M. Werner and J. M. Butler. 2007. Effect of source and concentration of Selenium on growth performance and selenium retention in broiler chickens. Poult. Sci. 86(4):727-730

49.
Zhao, L., D. Liu, P. Yang, P. Chen, W. X. Dong and D. M. Wang. 2008. Supplementation with selenium and vitamin E improves milk fat depression and fatty acid composition in dairy cows fed fat diet. Asian-Aust. J. Anim. Sci. 21(6):838-844

50.
Zhang, J. S., H. L. Wang and X. X Yan. 2005. Comparison of short-term toxicity between Nano-Se and selenite in mice. Life Sci. 76:1099-1109 crossref(new window)