Advanced SearchSearch Tips
Effects of the Chicken Sex-linked Dwarf Gene on Growth and Muscle Development
facebook(new window)  Pirnt(new window) E-mail(new window) Excel Download
 Title & Authors
Effects of the Chicken Sex-linked Dwarf Gene on Growth and Muscle Development
Chen, C.F.; Chen, Y.H.; Tixier-Boichard, M.; Cheng, P.Y.; Chang, C.S.; Tang, P.C.; Lee, Y.P.;
  PDF(new window)
The aim of this study was to analyze the effects on growth and muscle development during the growing period of the sex-linked dwarf gene in the background of a Taiwan Country chicken strain, L2, selected for egg production. Eight crossbred males, heterozygous for the DW*DW mutation, were each backcrossed to six females of the L2 strain to produce two genotypes of BC females, either normal (DW*N+/-) or dwarf (DW*DW/-). The experiment included 251 normal and 207 dwarf pullets. The effect of the dwarf gene on body weight and shank length was highly significant from 2 weeks of age. The reduction of body weight by the dwarf gene reached 34.8% and 37.4% as compared to normal sibs at 16 and 20 weeks of age, respectively. Parameters of the growth curve were estimated: the age at inflection (TI) was higher in normal pullets (66.9 days) than in dwarf pullets (61.2 days). A significant effect of the dwarf gene on single muscle fiber cross-section area was found from 12 weeks of age onwards, whereas the dwarf gene had no effect on the total number of muscle fibers. Comparing the effect of the dwarf gene on shank length at different ages revealed an earlier effect on skeleton growth, observed from 2 weeks of age, than on muscle development, which was affected from 8 to 12 weeks of age.
Growth Curve;Muscle Development;Sex-linked Dwarf Gene;Chicken;
 Cited by
Agarwal, S. K., L. A. Cogburn and J. Burnside. 1994. Dysfunctional growth hormone receptor in a strain of sexlinked dwarf chicken: evidence for a mutation in the intracellular domain. J. Endocrinol. 142:427-434 crossref(new window)

Decuypere, E., L. M. Huybrechts, E. R. Kuhn, M. Tixier-Boichard and P. Merat. 1991. Physiological alterations associated with the chicken sex-linked dwarfing gene. Crit. Rev. Poult. Boil. 3:191-221

Godfrey, E. F. 1953. The genetic control of growth and adult body weight in the domestic fowl. Poult. Sci. 32:248-259 crossref(new window)

Hutt, F. B. 1959. Sex-linked dwarfism in the fowl. J. Hered. 50:209-221

Islam, M. A. 2005. Sex-linked dwarf gene for broiler production in hot-humid climates. Asian-Aust. J. Anim. Sci. 18:1662-1668

Knizetova, H. 1993. Effects of the sex-linked dwarf gene (dw) on the skeletal muscle cellularity in broiler chickens. Br. Poult. Sci. 34:479-485 crossref(new window)

Laird, A. K., S. A. Tyler and A. D. Barton. 1965. Dynamics of normal growth. Growth 29:233-248

Landauer, W. 1929. Thyrogenous dwarfism (myxxoedema infantilis) in the domestic fowl. Ann. J. Anat. 43:1-43 crossref(new window)

Landauer, W. and L. C. Dunn. 1930. Studied of the creeper fowl. 1. Genetics. J. Gen. 23:397-413 crossref(new window)

M\acute{e}rat, P. 1990. Pleiotropic and associated effect of major genes. In: Poultry breeding and genetics (Ed. R. D. Crawford). Elsevier, Amsterdam, pp. 429-467

Mérat, P. 1984. The sex-linked dwarf gene in the broiler chicken industry. World's Poult. Sci. J. 40:10-18 crossref(new window)

Mignon-Grasteau, S., C. Beaumont, E. Le Bihan-Duval, J. P. Poivey, H. De Rochambeau and F. H. Ricard. 1999. Genetic parameters of growth curve parameters in male and female chickens. Br. Poult. Sci. 40:44-51

N'dri, A. L., S. Mignon-Grasteau, N. Sellier, M. Tixier-Boichard and C. Beaumont. 2006. Genetic relationships between feed conversion ratio, growth curve and body composition in slowgrowing chickens. Br. Poult. Sci. 47:273-280 crossref(new window)

Nierobisz, L. S. and P. E. Mozdziak. 2008. Factors influencing satellite cell activity during skeletal muscle development in avian and mammalian species. Asian-Aust. J. Anim. Sci. 21:456-464

Reddy, P. R. K. and P. Siegel. 1977. Selection for body weight at 8 weeks of age. 14. Effect of the sex-linked dwarf gene. Poult. Sci. 56:1004-1009 crossref(new window)

Rehfeldt, C., I. Fiedler, G. Dietl and K. Ender. 2000. Myogenesis and postnatal skeletal muscle cell growth as influenced by selection. Livest. Prod. Sci. 66:177-188 crossref(new window)

Rehfeldt, C., I. Fiedler and N. C. Stickland. 2004. Number and size of muscle fibers in relation to meat production. In: Muscle development of livestock animal (Ed. M. F. W. te Pas, M. E. Everts and H. P. Haagsman). CABI, UK, pp. 1-38

R\acute{e}mignon, H., M. F. Gardahaut, G. March\grave{e} and F. H. Ricard. 1995. Selection for rapid growth increases the number and the size of muscle fibers without changing their typing in chickens. J. Muscl. Res. Cell Motil. 16:95-102 crossref(new window)

SAS Institute. 2002. The SAS System for Windows. Release 9.1 SAS Inst. Inc., Cary, NC