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Effects of Dietary Alpha-lipoic Acid on Anti-oxidative Ability and Meat Quality in Arbor Acres Broilers
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 Title & Authors
Effects of Dietary Alpha-lipoic Acid on Anti-oxidative Ability and Meat Quality in Arbor Acres Broilers
Zhang, Y.; Hongtrakul, Kittiporn; Ji, C.; Ma, Qiugang; Liu, L.T.; Hu, X.X.;
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 Abstract
An experiment was conducted to evaluate the effects of dietary alpha-lipoic acid (LA) on growth performance, carcass characteristics and meat quality in Arbor Acres broilers. A total of 240 1-d-old male Arbor Acres broilers were randomly allocated to 4 dietary treatments (0, 300 ppm, 600 ppm, and 900 ppm dietary LA supplementation, respectively). Birds were slaughtered at 42 days old. Live body weight (BW), average daily gain (ADG), average feed intake (AFI), feed conversion ratio (FCR), dressing percentage, breast muscle percentage, thigh muscle percentage, abdominal fat percentage, muscle color (L*, a*, b*), pH values at 24 h postmortem, meat shear force value (SFV) and anti-oxidative ability were measured. Results showed that addition of 600 ppm or 900 ppm LA decreased BW (p<0.01), ADG (p<0.01) and AFI (p<0.05) compared with other diets. FCR was not affected by dietary LA content. LA had no marked effect on dressing percentage, breast muscle percentage or thigh muscle percentage. Abdominal fat percentage was lower (p<0.05) in the 900 ppm LA supplementation group than the control group. Dietary 900 ppm LA increased (p<0.05) breast and thigh muscle pH value at 24 h postmortem compared with the control treatment. Dietary LA increased thigh muscle a* value, though no significant difference was found in thigh muscle a* value among the treatments. Dietary LA significantly decreased breast muscle L* value (p<0.05), breast muscle b* value (p<0.01) and thigh muscle b* value (p<0.05). Broilers fed LA had higher breast muscle a* value (p<0.05) and thigh muscle L* value (p<0.05). All test groups had lower (p<0.05) breast muscle SFV than the control group. Dietary 600 ppm or 900 ppm LA both decreased (p<0.01) thigh muscle SFV compared with the control treatment. Dietary 900 ppm LA significantly increased (p<0.05) TAOC, SOD and GSHPx compared with no LA treatment. Broilers fed LA had lower (p<0.01) MDA compared with the control treatment. These results suggested that dietary LA enhanced the anti-oxidative ability and oxidative stability, and contributed to the improvement of meat quality in broilers.
 Keywords
Alpha-lipoic Acid;Carcass Traits;Meat Quality;Anti-oxidative Ability;Broiler;
 Language
English
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Protective Efficacy of Alpha-lipoic Acid against AflatoxinB1-induced Oxidative Damage in the Liver, Asian-Australasian Journal of Animal Sciences, 2014, 27, 6, 907  crossref(new windwow)
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Effects of Dietary L-carnosine and Alpha-lipoic Acid on Growth Performance, Blood Thyroid Hormones and Lipid Profiles in Finishing Pigs, Asian-Australasian Journal of Animal Sciences, 2015, 28, 10, 1465  crossref(new windwow)
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 References
1.
Andersson, U., K. Filipsson, C. R. Abbott, A. Woods, K. Smith, S. R. Bloom, D. Carling and C. J. Small. 2004. AMP-activated protein kinase plays a role in the control of food intake. J. Biol. Chem. 279:12005-12008 crossref(new window)

2.
Berg, E. P., K. R. Maddock and M. L. Linville. 2003. Creatine monohydrate supplemented in swine finishing diets and fresh pork quality: III. Evaluating the cumulative effect of creatine monohydrate and alpha-lipoic acid. J. Anim. Sci. 81:2469-2474

3.
Boulianne, M. and A. J. King. 1995. Biochemical and color characteristics of skinless boneless pale chicken breast. Poult. Sci. 74:1693-1698

4.
Boulianne, M. and A. J. King. 1998. Meat color and biochemical characteristics of unacceptable dark-colored broiler chicken carcasses. J. Food. Sci. 63:759-762 crossref(new window)

5.
Calkins, C. R., T. R. Dutson, G. C. Smith and Z. L. Carpenter. 1982. Concentrations of creatine phosphate, adenine nucleotides and their derivatives in electrically stimulated and non-stimulated beef muscle. J. Food Sci. 47:1350-1353 crossref(new window)

6.
Calkins, C. R. and S. C. Seideman. 1988. Relationships among calcium-dependent protease, cathepsins B and H, meat tenderness and the response of muscle to aging. J. Anim. Sci. 66:1186-1193

7.
Dilger, R. N., C. Martinez Amezcua, P. B. Pillai, J. L. Emmert, C. M. Parsons and D. H. Baker. 2006. Effect of Reciprocating dietary lysine fluctuations on chick growth and carcass yield. Poult. Sci. 85:1226-1231

8.
Fletcher, D. L. 1999. Broiler breast meat color variation, pH and meat texture. Poult. Sci. 78:1323-1327

9.
Goes, V. A., J. Brouwer, K. Hoekstra, D. Roos, T. K. van den Berg and C. D. Dijkstra. 1998. Reactive oxygen species are required for the phagocytosis of myelin by macrophages. J. Neuroimmunol. 92:67-75 crossref(new window)

10.
Goll, Darrel E., D. W. Henderson and E. A. Kline. 1964. Postmortem changes in physical and chemical properties of bovine muscle. J. Food Sci. 29:590-596 crossref(new window)

11.
Hamano, Y., Y. Kamota and S. Sugawara. 2000. Effects of lipic acid on plasma metabolites and metabolic response to intravenous injection of isoproterenol in broilers. Asian-Aust. J. Sci. 13:653-658

12.
Haramaki, N., D. Han, G. J. Handelman, H. J. Tritschler and L. Packer. 1997. Cytosolic and mitochondrial systems for NADH- and NADPH-dependent reduction of alpha-lipoic acid. Free Radic. Biol. Med. 22:535-542 crossref(new window)

13.
Jiang, S. Q., Z. Y. Jiang, Y. C. Lin, P. B. Xi and X. Y. Ma. 2007. Effects of soy isoflavone on performance, meat quality and antioxidative property of male broilers fed oxidized fish oil. Asian-Aust. J. Anim. Sci. 20:1252-1257

14.
Jiang, Z. Y., S. Q. Jiang, Y. C. Lin, X. Y. Ma, P. B. Xi, T. Cao and X. Q. Wang. 2008. Effect of genistein on antioxidative defense system and membrane fluidity in chick skeletal muscle cells. Asian-Aust. J. Anim. Sci. 21:1220-1225

15.
Kim, M. S., J. Y. Park, C. Namkoong, P. G. Jang, J. W. Ryu, H. S. Song, J. Y. Yun, I. S. Namqoonq, J. Ha, I. S. Park, I. K. Lee, B. Viollet, J. H. Youn, H. K. Lee and K. U. Lee. 2004. Antiobesity effects of alpha-lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase. Nat. Med. 10:727-733 crossref(new window)

16.
Kowluru, R. A., S. Odenbach and S. Basak. 2005. Long-term administration of lipoic acid inhibits retinopathy in diabetic rats via regulating mitochondrial superoxide dismutase. Invest Ophthalmol. Vis. Sci. 46:422-428

17.
Lin, H., E. Decuypere and J. Buyse. 2008. Effect of thyroid hormones on the redox balance of broiler chickens. Asian-Aust. J. Anim. Sci. 21:794-800

18.
Lindahl, G., K. Lundstrom and E. Tornberg. 2001. Contribution of pigment content, myoglobin forms and internal reflectance to the colour of pork loin and ham from pure breed pigs. Meat Sci. 59:141-151 crossref(new window)

19.
Lister, D., R. A. Sair, J. A. Will, G. R. Schmidt, R. G. Cassens, W. G.. Hoekstra and E. J. Briskey. 1970. Metabolism of striated muscle of stress-susceptible pigs breathing oxygen or nitrogen. Am. J. Physiol. 218: 102-107

20.
Liu, J. K. 2008. The Effects and Mechanisms of Mitochondrial Nutrient a-Lipoic Acid on Improving Age-Associated Mitochondrial and Cognitive Dysfunction: An Overview. Neurochem. Res. 33: 194–203 crossref(new window)

21.
Maddock, E. P. Berg, C. A. Stahl, M. L. Linville and J. A. Carroll. 2001. The effects of alpha lipoic acid (LA) on performance and health of weaned neonatal pigs. J. Anim. Sci. 79 (Suppl.1): 756-764

22.
Minokoshi, Y., T. Alquier, N. Furukawa, Y. B. Kim, A. Lee, B. Z. Xue, J. Mu, F. Foufelle, P. Ferre, M. J. Birnbaum, B. J. Stuck and B. B. Kahn. 2004. AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus. Nature. 428: 569–574 crossref(new window)

23.
Moini, H., L. Packer and N. L. Saris. 2002. Antioxidant and prooxidant activities of α-lipoic acid and dihydrolipoic acid. Toxicol. Appl. Pharmacol. 182: 84–90 crossref(new window)

24.
NRC. 1994. Nutrient Requirements of Poultry. 9th rev. ed. National Academy Press, Washington, DC. (SF494.N37)

25.
Packer, L., E. H. Witt and H. J. Tritschler. 1995. Alpha-lipoic acid as a biological antioxidant. Free Radic. Biol. Med 19: 227–250 crossref(new window)

26.
Packer, L., H. J. Tritschler and K. Wessel. 1997a. Neuroprotection by the metabolic antioxidant α-lipoic acid. Free Radic. Biol. Med. 22:359-378 crossref(new window)

27.
Packer, L., S. Roy and C. K. Sen. 1997b. Alpha-lipoic acid: a metabolic antioxidant and potential redox modulator of transcription. Adv. Pharmacol. 38:79-101

28.
Reed, J. K. 1973. Studies on the kinetic mechanism of lipoamide dehydrogenase from rat liver mitochondria. J. Biol. Chem. 13:4834-4839 crossref(new window)

29.
Rentfrow, G., M. L. Linville, C. A. Stahl, K. C. Olson and E. P. Berg. 2004. The effects of the antioxidant lipoic acid on beef longissimus bloom time. J. Anim. Sci. 82:3034-3037

30.
Rosenvold, K., B. Essén-Gustavsson and H. J. Andersen. 2003. Dietary manipulation of pro- and macroglycogen in porcine skeletal muscle. J. Anim. Sci. 81:130-134

31.
Rybak, L. P., K. Husain, C. Whitworth and S. M. Somani. 1999. Dose dependent protection by lipoic acid against cisplatininduced ototoxicity in rats: antioxidant defense system. Toxicological Sciences 47:195-202 crossref(new window)

32.
Ryu, Y. C., M. S. Rhee, K. M. Lee and B. C. Kim. 2005. Effects of different levels of dietary supplemental selenium on performance, lipid oxidation, and color stability of broiler chicks. Poult. Sci. 84:809-815

33.
Schmidt, T. B., K. C. Olson, PAS, D. L. Meyer, M. M. Brandt, G. K. Rentfrow, C. A. Stahl and E. P. Berg. 2005. Effects of lipoic acid supplementation on finishing steer growth performance, carcass merit, beef tenderness, and beef retail display properties. Professional Animal Scientist 21:480-485

34.
Sen, C. K., S. Roy, D. Han and L. Packer. 1997. Regulation of cellular thiols in human lymphocytes by α-lipoic acid: a flow cytometric analysis. Free Radic. Biol. Med. 22:1241-1257 crossref(new window)

35.
Shen, Q. W., C. S. Jones, N. Kalchayanand, M. J. Zhu and M. Du. 2005. Effect of dietary α-lipoic acid on growth, body composition, muscle pH, and AMP-activated protein kinase phosphorylation in mice. J. Anim. Sci. 83:2611-2617

36.
Shen, Q. W. and M. Du. 2005. Effects of dietary α-lipoic acid on glycolysis of postmortem muscle. Meat Sci. 71:306-311 crossref(new window)

37.
Tang, M. Y., Q. G. Ma, X. D. Chen and C. Ji. 2007. Effects of dietary metabolizable energy and lysine on carcass characteristics and meat quality in Arbor Acres broilers. Asian-Aust. J. Anim. Sci. 20:1865-1873

38.
Tsai, H. L., Sam K. C. Chang, Y. F. Lin and S. J. Chang. 2008. Beneficial effects of maternal vitamin E supplementation on the antioxidant system of the neonate chick brain. Asian-Aust. J. Anim. Sci. 21:225-231

39.
Wheeler, T. L. and M. Koohmaraie. 1994. Prerigor and postrigor changes in tenderness of ovine longissimus muscle. J. Anim. Sci. 72:1232-1238

40.
Woelfel, R. L., C. M. Owens, E. M. Hirschler, R. Martinez-Dawson and A. R. Sams. 2002. The characterization and incidence of pale, soft, exudative broiler meat in a commercial plant. Poult. Sci. 81:579-584

41.
Young, J. F., J. Stagsted, S. K. Jensen, A. H. Karlsson and P. Henckel. 2003. Ascorbic acid, alpha-tocopherol, and oregano supplements reduce stress-induced deterioration of chicken meat quality. Poult. Sci. 82:1343-1351