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Regulation of Fat and Fatty Acid Composition in Beef Cattle
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 Title & Authors
Regulation of Fat and Fatty Acid Composition in Beef Cattle
Smith, Stephen B.; Gill, Clare A.; Lunt, David K.; Brooks, Matthew A.;
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 Abstract
Fat composition of beef, taken here to mean marbling, can be manipulated by time on feed, finishing diet, and breed type. These three factors also strongly influence the fatty acid composition of beef. Both the amount of marbling and the concentration of monounsaturated fatty acids (MUFA) increase with time on feed in grain-fed and pasture-fed cattle, but much more dramatically in grain-fed cattle. High-concentrate diets stimulate the activity of adipose tissue stearoyl-CoA desaturase (SCD), which is responsible for the conversion of saturated fatty acids (SFA) to their desaturated counterparts. Also, grain feeding causes a depression in ruminal pH, which decreases those populations of ruminal microorganisms responsible for the isomerization and hydrogenation of polyunsaturated fatty acids (PUFA). The net result of elevated SCD activity in marbling adipose tissue and depressed ruminal isomerization/hydrogenation of dietary PUFA is a large increase in MUFA in beef over time. Conversely, pasture depresses both the accumulation of marbling and SCD activity, so that even though pasture feeding increases the relative concentration of PUFA in beef, it also increases SFA at the expense of MUFA. Wagyu and Hanwoo cattle accumulate large amounts of marbling and MUFA, and Wagyu cattle appear to be less sensitive to the effects of pastures in depressing overall rates of adipogenesis and the synthesis of MUFA in adipose tissues. There are small differences in fatty acid composition of beef from Bos indicus and Bos taurus cattle, but diet and time on feed are much more important determinants of beef fat content and fatty acid composition than breed type.
 Keywords
Adipose Tissue;Bovine;Fatty Acids;Intramuscular;Stearoyl-CoA Desaturase;
 Language
English
 Cited by
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 References
1.
Archibeque, S. L., D. K. Lunt, C. D. Gilbert, R. K. Tume and S. B. Smith. 2005. Fatty acid indices of stearoyl-CoA desaturase do not reflect actual stearoyl-CoA desaturase enzyme activities in adipose tissues of beef steers finished with corn-, flaxseed-, or sorghum-based diets. J. Anim. Sci. 83:1153-1166

2.
Cameron, P. J., M. Rogers, J. Oman, S. G. May, D. K. Lunt and S. B. Smith. 1994. Stearoyl-CoA desaturase enzyme activity and mRNA levels are not different in subcutaneous adipose tissue from Angus and American Wagyu steers. J. Anim. Sci. 72:2624-2628

3.
Casimir, D. and J. M. Ntambi. 1996. cAMP activates the expression of stearoyl-CoA desaturase gene 1 during early preadipocyte differentiation. J. Biol. Chem. 271:29847-29853 crossref(new window)

4.
Chang, J. H. P., D. K. Lunt and S. B. Smith. 1992. Fatty acid composition and fatty acid elongase and stearoyl-CoA desaturase activities in tissues of steers fed high oleate sunflower seed. J. Nutr. 122:2074-2080

5.
Choi, Y., Y. Park, M. W. Pariza and J. M. Ntambi. 2001. Regulation of stearoyl-CoA desaturase activity by the trans-10,cis-12 isomer of conjugated linoleic acid in HepG2 cells. Biochem. Biophys. Res. Commun. 284:689-693 crossref(new window)

6.
Choi, Y., Y. Park, J. M. Storkson, M. W. Pariza and J. M. Ntambi. 2002. Inhibition of stearoyl-CoA desaturase activity by the cis-9,trans-11 isomer and the trans-10,cis-12 isomer of conjugated linoleic acid in MDA-MB-231 and MCF-7 human breast cancer cells. Biochem. Biophys. Res. Commun. 294:785-790 crossref(new window)

7.
Chung, K.Y., D. K. Lunt, C. B. Choi, S. H. Chae, R. D. Rhoades, T. H. Adams, B. Booren and S. B. Smith. 2006b. Lipid characteristics of subcutaneous adipose tissue and M. longissimus thoracis of Angus and Wagyu steers fed to U.S. and Japanese endpoints. Meat Sci. 73:432-441 crossref(new window)

8.
Chung, K. Y., D. K. Lunt, H. Kawachi, H. Yano and S. B. Smith. 2007. Lipogenesis and stearoyl-CoA desaturase gene expression and enzyme activity in adipose tissue of short- and long-fed Angus and Wagyu steers fed corn- or hay-based diets. J. Anim. Sci. 85:380-387 crossref(new window)

9.
Chung, K. Y., C. B. Choi, H. Kawachi, H. Yano and S. B. Smith. 2006a. Trans-10, cis-12 conjugated linoleic acid antagonizes arginine-promoted differentiation of bovine preadipocytes. Adipocytes 2:93-100

10.
Daniel, Z. C., R. J. Wynn, A. M. Salter and P. J. Buttery. 2004. Differing effects of forage and concentrate diets on the oleic acid and conjugated linoleic acid content of sheep tissues: the role of stearoyl-CoA desaturase. J. Anim. Sci. 82:747-758

11.
Devillard, E., F. M. McIntosh, C. J. Newbold and R. J. Wallace. 2006. Rumen ciliate protozoa contain high concentrations of conjugated linoleic acids and vaccenic acid, yet do not hydrogenate linoleic acid or desaturate stearic acid. Br. J. Nutr. 96:697-704

12.
Duckett, S. K., S. L. Pratt and E. Pavan. 2009. Corn oil or corn grain supplementation to steers grazing endophyte-free tall fescue. II. Effects on subcutaneous fatty acid content and lipogenic gene expression. J. Anim. Sci. 87:1120-1128 crossref(new window)

13.
Ekeren, P. A., D. R. Smith, D. K. Lunt and S. B. Smith. 1992. Ruminal biohydrogenation of fatty acids from high-oleate sunflower seeds. J. Anim. Sci. 70:2574-2580 crossref(new window)

14.
Fukuda, S., Y. Suzuki, M. Murai, N. Asanuma and T. Hino. 2006. Augmentation of vaccenate production and suppression of vaccenate biohydrogenation in cultures of mixed ruminal microbes. J. Dairy Sci. 89:1043-1051 crossref(new window)

15.
Huerta-Leidenz, N. O., H. R. Cross, J. W. Savell, D. K. Lunt, J. F. Baker, L. S. Pelton and S. B. Smith. 1993. Comparison of the fatty acid composition of subcutaneous adipose tissue from mature Brahman and Hereford cows. J. Anim. Sci. 71:625-630

16.
Huerta-Leidenz, N. O., H. R. Cross, J. W. Savell, D. K. Lunt, J. F. Baker and S. B. Smith. 1996. Fatty acid composition of subcutaneous adipose tissue from male calves at different stages of growth. J. Anim. Sci. 74:1256-1264

17.
Jiang, Z., J. J. Michal, D. J. Tobey, T. F. Daniels, D. C. Rule and M. D. MacNeil. 2008. Significant associations of stearoyl-CoA desaturase (SCD1) gene with fat deposition and composition in skeletal muscle. Int. J. Biol. Sci. 4:345-351

18.
Jung, K. K. and C. B. Choi. 2003. Development of technologies to improve competitiveness of Hanwoo. Report to the Ministry of Agriculture, pp. 85-98. Seoul, Korea

19.
Kucek, O., B. W. Hess, P. A. Ludden and D. C. Rule. 2001. Effect of forage:concentrate ratio on ruminal digestion and duodenal flow of fatty acids in ewes. J. Anim. Sci. 79:2233-2240

20.
Lee, S. H., D. H. Yoon, N. J. Choi, S. H. Hwang, E. Y. Cheong, S. J. Oh, I. C. Cheong and C. S. Lee. 2005. Developmental relationship of unsaturated fatty acid composition and stearoyl-CoA desaturase mRNA level in Hanwoo steers' muscle. Asian-Aust. J. Anim. Sci. 18:562-566

21.
Lunt, D. K., C. B. Choi, K. Y. Chung and S. B. Smith. 2005. Production characteristics and carcass quality of Angus and Wagyu steers raised to US and Japanese endpoints. Journal of Animal and Veterinary Advances 4:949-953

22.
Lunt, D. K., R. R. Riley and S. B. Smith. 1993. Growth and carcass characteristics of Angus and American Wagyu Steers. Meat Sci. 34:327-334 crossref(new window)

23.
Malau-Aduli, A. E. O., B. D. Siebert, C. D. K. Bottema and W. S. Pitchford. 1997. A comparison of the fatty acid composition of triacylglycerols in adipose tissue from Limousin and Jersey cattle. Aust. J. Agric. Res. 48:715-722 crossref(new window)

24.
Malau-Aduli, A. E. O., B. D. Siebert, C. D. K. Bottema and W. S. Pitchford. 1998. Breed comparisons of the fatty acid composition of muscle phospholipids in Jersey and Limousin cattle. J. Anim. Sci. 76:766-773

25.
Martin, G. S., D. K. Lunt, K. G. Britain and S. B. Smith. 1999. Postnatal development of stearoyl coenzyme A desaturase gene expression and adiposity in bovine subcutaneous adipose tissue. J. Anim. Sci. 77:630-636

26.
May, S. G., C. A. Sturdivant, D. K. Lunt, R. K. Miller and S. B. Smith. 1993. Comparison of sensory characteristics and fatty acid composition between Wagyu crossbred and Angus steers. Meat Sci. 35:289-298 crossref(new window)

27.
Or-Rashid, M. M., N. E. Odongo and B. W. McBride. 2007. Fatty acid composition of ruminal bacteria and protozoa, with emphasis on conjugated linoleic acid, vaccenic acid, and oddchain and branched-chain fatty acids. J. Anim. Sci. 85:1228-1234 crossref(new window)

28.
Pitchford, W. S., M. P. B. Deland, B. D. Siebert, A. E. O. Malau-Aduli and C. D. K. Bottema. 2002. Genetic variation in fatness and fatty acid composition of crossbred cattle. J. Anim. Sci. 80:2825-2832

29.
Rule, D. C., M. D. MacNeil and R. E. Short. 1997. Influence of sire growth potential, time on feed, and growing-finishing strategy on cholesterol and fatty acids of the ground carcass and longissimus muscle of beef steers. J. Anim. Sci. 75:1525-1533

30.
Smith, S. B., A. Yang, T. W. Larsen and R. K. Tume. 1998. Positional analysis of triacylglycerols from bovine adipose tissue lipids varying in degree of unsaturation. Lipids 33:197-207 crossref(new window)

31.
Smith, S. B., M. Zembayashi, D. K. Lunt, J. O. Sanders and C. D. Gilbert. 2001. Carcass traits and microsatellite distributions of offspring of sires from three geographical regions of Japan. J. Anim. Sci. 79:3041-3051 crossref(new window)

32.
St John, L. C., D. K. Lunt and S. B. Smith. 1991. Fatty acid elongation and desaturation enzyme activities of bovine liver and subcutaneous adipose tissue microsomes. J. Anim. Sci. 69:1064-1073

33.
St. John, L. C., C. R. Young, D. A. Knabe, G. T. Schelling, S. M. Grundy and S. B. Smith. 1987. Fatty acid profiles and sensory and carcass traits of tissues from steers and swine fed an elevated monounsaturated fat diet. J. Anim. Sci. 64:1441-1447

34.
Sturdivant, C. A., D. K. Lunt, C. Smith and S. B. Smith. 1992. Fatty acid composition of subcutaneous and intramuscular adipose tissues and M. longissimus dorsi of Wagyu cattle. Meat Sci. 32:449-458 crossref(new window)

35.
Taylor, J. F., L. L. Coutinho, K. K. Herring, D. S. Gallagher, R. A. Brenneman, N. Burney, J. O. Sanders, J. W. Turner, S. B. Smith, R. K. Miller, J. W. Savell and S. K. Davis. 1998. Candidate gene analysis of GH1 for effects on growth and carcass characteristics of cattle. Anim. Genet. 29:194-201 crossref(new window)

36.
Vossenberg, J. L. C. M. and K. N. Joblin. 2003. Biohydrogenation of c18 unsaturated fatty acids to stearic acid by a strain of butyrivibrio hungatei from the bovine rumen. Lett. Appl. Microbiol. 37:424-428 crossref(new window)

37.
Waldman, R. C., G. G. Suess and V. H. Brungardt. 1968. Fatty acids of certain bovine tissue and their association with growth, carcass and palatability traits. J. Anim. Sci. 27:632-635

38.
Wallace, J. R., L. C. Chaudhary, N. McKain, N. R. McEwan, A. J. Richardson, P. E. Vercoe, N. D. Walker and D. Paillard. 2006. Clostridium proteoclasticum: A ruminal bacterium that forms stearic acid from linoleic acid. FEMS Microbiol. Lett. 265:195-201 crossref(new window)

39.
Waters, S. M., J. P. Kelly, P. O'Boyle, A. P. Moloney and D. A. Kenny. 2009. Effect of level and duration of dietary n-3 polyunsaturated fatty acid supplementation on the transcriptional regulation of $\Delta$9-desaturase in muscle of beef cattle. J. Anim. Sci. 87:244-253 crossref(new window)

40.
Westerling, D. B. and H. B. Hedrick. 1979. Fatty acid composition of bovine lipids as influenced by diet, sex and anatomical location and relationship to sensory characteristics. J. Anim. Sci. 48:1343-1348 crossref(new window)

41.
Wood, J. D., R. I. Richardson, G. R. Nute, A. V. Fisher, M. M. Campo, E. Kasapidou, P. R. Sheard and M. Enser. 2004. Effects of fatty acids on meat quality: a review. Meat Sci. 66:21-32 crossref(new window)

42.
Zembayashi, M., D. K. Lunt and S. B. Smith. 1999. Dietary tea reduces the iron content of beef. Meat Sci. 53:221-226 crossref(new window)

43.
Zembayashi, M., K. Nishimura, D. K. Lunt and S. B. Smith. 1995. Effect of breed type and sex on the fatty acid composition of subcutaneous and intramuscular lipids of finishing steers and heifers. J. Anim. Sci. 73:3325-3332

44.
Zembayashi, M. 1994. Beef production. Yokendo, Ltd., Tokyo, Japan