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Effect of Corticosterone on Hypothalamic Corticotropin-releasing Hormone Expression in Broiler Chicks (Gallus gallus domesticus) Fed a High Energy Diet
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 Title & Authors
Effect of Corticosterone on Hypothalamic Corticotropin-releasing Hormone Expression in Broiler Chicks (Gallus gallus domesticus) Fed a High Energy Diet
Song, Zhigang; Yuan, Lei; Jiao, Hongchao; Lin, Hai;
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 Abstract
This paper reports the peripheral and central effect of corticosterone on feed intake and hypothalamic corticotropinreleasing hormone (CRH) gene expression in chicks fed a high energy diet. Three experiments were conducted: corticosterone was supplemented to the feed (30 mg/kg diet), injected subcutaneously (s.c., 4 mg/kg body weight) or intracerebroventricularly (i.c.v., 4 ng). The results showed that dietary corticosterone significantly increased feed intake. The s.c. corticosterone administration increased feed intake within 1 to 3 h and at 1 to 5 h after the injection. The i.c.v. corticosterone administration increased feed intake within 1 h after the injection, but not at 1 to 3 h. Dietary supplementation and s.c. injection of corticosterone decreased the CRH gene expression in the hypothalamus. Therefore, peripheral corticosterone exerted a decreased effect on hypothalamic CRH mRNA levels, and corticosterone had a stimulating effect on feed intake in broiler chicks fed a high energy diet.
 Keywords
Broiler Chicks;Corticosterone;Corticotropin-releasing Hormone;Feed Intake;
 Language
English
 Cited by
1.
Forsythia suspensa extract attenuates corticosterone-induced growth inhibition, oxidative injury, and immune depression in broilers, Poultry Science, 2014, 93, 7, 1774  crossref(new windwow)
2.
Effect of dexamethasone on hypothalamic expression of appetite-related genes in chickens under different diet and feeding conditions, Journal of Animal Science and Biotechnology, 2016, 7, 1  crossref(new windwow)
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