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Association of Chicken Growth Hormones and Insulin-like Growth Factor Gene Polymorphisms with Growth Performance and Carcass Traits in Thai Broilers
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 Title & Authors
Association of Chicken Growth Hormones and Insulin-like Growth Factor Gene Polymorphisms with Growth Performance and Carcass Traits in Thai Broilers
Nguyen, Thi Lan Anh; Kunhareang, Sajee; Duangjinda, Monchai;
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Molecular marker selection has been an acceptable tool in the acceleration of the genetic response of desired traits to improve production performance in chickens. The crossbreds from commercial parent stock (PS) broilers with four Thai synthetic breeds; Kaen Thong (KT), Khai Mook Esarn (KM), Soi Nin (SN), and Soi Pet (SP) were used to study the association among chicken growth hormones (cGH) and the insulin-like growth factor (IGF-I) genes for growth and carcass traits; for the purpose of developing a suitable terminal breeding program for Thai broilers. A total of 408 chickens of four Thai broiler lines were genotyped, using polymerase chain reaction-restriction fragment length polymorphism methods. The cGH gene was significantly associated with body weight at hatching; at 4, 6, 8, 10 weeks of age and with average daily gain (ADG); during 2 to 4, 4 to 6, 0 to 6, 0 to 8, and 0 to 10 weeks of age in chickens. For populations, cGH gene showed significant association with body weight at hatching, and ADG; during 8 to 10 weeks of age. The single nucleotide polymorphism variant confirmed that allele G has positive effects for body weight and ADG. Within carcass traits, cGH revealed a tentative association within the dressing percentage. For the IGF-I gene polymorphism, there were significant associations with body weight at hatching; at 2, 4, and 6 weeks of age and ADG; during 0 to 2, 4 to 6, and 0 to 6 weeks of age; in all of four Thai broiler populations. There were tentative associations of the IGF-I gene within the percentages of breast muscles and wings. Thus, cGH gene may be used as a candidate gene, to improve growth traits of Thai broilers.
cGH Gene;IGF-I Gene;Polymerase Chain Reaction-Restriction Fragment Length Polymorphism;Marker Assisted Selection;Thai Broilers;
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Amills, M., N. Jimenez, D. Villalba, M. Tor, E. Molina, D. Cubilo, C. Marcos, A. Francesch, A. Sanchez, and J. Estany. 2003. Identification of three single nucleotide polymorphisms in the chicken insulin-like growth factor 1 and 2 genes and their associations with growth and feeding traits. Poult. Sci. 82:1485-1493. crossref(new window)

Apa, R., A. Lanzone, F. Miceli, M. Mastrandrea, A. Caruso, S. Mancuso, and R. Canipari. 1994. Growth hormone induces in vitro maturation of follicle-and cumulus-enclosed rat oocytes. Mol. Cell. Endocrinol. 106:207-212. crossref(new window)

Ballard, F. J., R. J. Johnson, P. C. Owens, G. L. Francis, F. M. Upton, J. P. McMurtry, and J. C. Wallace. 1990. Chicken insulin-like growth factor-I: Amino acid sequence, radioimmunoassay, and plasma levels between strains and during growth. Gen. Comp. Endocrinol. 79:459-468. crossref(new window)

Beccavin, C., B. Chevalier, L. Cogburn, J. Simon, and M. Duclos. 2001. Insulin-like growth factors and body growth in chickens divergently selected for high or low growth rate. J. Endocrinol. 168:297-306. crossref(new window)

Boschiero, C., E. C. Jorge, K. Ninov, K. Nones, M. F. do Rosario, L. L. Coutinho, M. C. Ledur, D. W. Burt, and A. S. A. Moura. 2013. Association of IGF1 and KDM5A polymorphisms with performance, fatness and carcass traits in chickens. J. Appl. Genet. 54:103-112. crossref(new window)

Byatt, J. C., N. R. Staten, W. J. Salsgiver, J. G. Kostelc, and R. J. Collier. 1993. Stimulation of food intake and weight gain in mature female rats by bovine prolactin and bovine growth hormone. Am. J. Physiol. 264:E986-E992. crossref(new window)

Denley, A., L. J. Cosgrove, G. W. Booker, J. C. Wallace, and B. E. Forbes. 2005. Molecular interactions of the IGF system. Cytokine Growth Factor Rev. 16:421-439. crossref(new window)

Falconer, D. S. and T. F. C. Mackay. 2001. Introduccion a la genetica cuantitativa. Editorial Acribia, Zaragoza, Spain.

Feng, X. P., U. Kuhnlein, S. E. Aggrey, J. S. Gavora, and D. Zadworny. 1997. Trait association of genetic markers in the growth hormone and the growth hormone receptor gene in a White Leghorn strain. Poult. Sci. 76:1770-1775. crossref(new window)

Goodwin, W., A. Linacre, and S. Hadi. 2007. An introduction to forensic genetics. John Wiley & Sons, Chichester, England.

Hrabia, A., H. E. Paczoska-Eliasiewicz, L. R. Berghman, S. Harvey, and J. Rząsa. 2008. Expression and localization of growth hormone and its receptors in the chicken ovary during sexual maturation. Cell Tissue Res. 332:317-328. crossref(new window)

Jaturasitha, S., T. Srikanchai, M. Kreuzer, and M. Wicke. 2008. Differences in carcass and meat characteristics between chicken indigenous to northern Thailand (Black-boned and Thai native) and imported extensive breeds (Bresse and Rhode Island Red). Poult. Sci. 87:160-169. crossref(new window)

Kansaku, N., G. Hiyama, T. Sasanami, and D. Zadworny. 2008. Prolactin and growth hormone in birds: Protein structure, gene structure and genetic variation. J. Poult. Sci. 45:1-6. crossref(new window)

Kaya, M. and M. A. Yildiz. 2008. Genetic diversity among Turkish native chickens, Denizli and Gerze, estimated by microsatellite markers. Biochem. Genet. 46:480-491. crossref(new window)

Kita, K. and J. Okumura. 2001. Chicken insulin-like growth factor-I stimulates protein synthesis of chicken embryo myoblasts cultured in serum-free medium. Asian Australas. J. Anim. Sci. 14:17-20. crossref(new window)

Mehdi, A. and F. A. Reza. 2012. Single nucleotide Polymorphisms in intron 1 of growth hormone gene and it's association with economic important traits in Iranian Fars native fowl. Ann. Biol. Res. 3:4028-4032.

Mu'in, M. and S. Lumatauw. 2013. Identification of MspI polymorphism in the forth intron of chicken growth hormone gene and their associations with growth traits in Indonesia native chickens. Anim. Prod. 15:1-7.

Nie, Q., B. Sun, D. Zhang, C. Luo, N. A. Ishag, M. Lei, G. Yang, and X. Zhang. 2005. High diversity of the chicken growth hormone gene and effects on growth and carcass traits. J. Hered. 96:698-703. crossref(new window)

Piper, M. M. and T. E. Porter. 1997. Responsiveness of chicken embryonic somatotropes to somatostatin (SRIF) and IGF-I. J. Endocrinol. 154:303-310. crossref(new window)

Promwatee, N., B. Laopaiboon, T. Vongpralub, Y. Phasuk, S. Kunhareang, W. Boonkum, and M. Duangjinda. 2013. Insulinlike growth factor I gene polymorphism associated with growth and carcass traits in Thai synthetic chickens. Genet. Mol. Res. 12:4332-4341. crossref(new window)

Rousseau, K. and S. Dufour. 2007. Comparative aspects of GH and metabolic regulation in lower vertebrates. Neuroendocrinology 86:165-174. crossref(new window)

Scanes, C. G. 2009. Perspectives on the endocrinology of poultry growth and metabolism. Gen. Comp. Endocrinol. 163:24-32. crossref(new window)

Spencer, G. S., J. Buyse, E. Decuypere, and G. Rahimi. 1997. Physiological inhibition of growth hormone secretion by both insulin‐like growth factors‐I and‐II in chickens. Br. Poult. Sci. 38:429-431. crossref(new window)

Vasilatos-Younken, R., Y. Zhou, X. Wang, J. P. McMurtry, R. W. Rosebrough, E. Decuypere, N. Buys, V. M. Darras, S. Van Der Geyten, and F. Tomas. 2000. Altered chicken thyroid hormone metabolism with chronic GH enhancement in vivo: consequences for skeletal muscle growth. J. Endocrinol. 166:609-620. crossref(new window)

Wattanachant, S., S. Benjakul, and D. A. Ledward. 2004. Composition, color, and texture of Thai indigenous and broiler chicken muscles. Poult. Sci. 83:123-128. crossref(new window)

Yan, B., X. Deng, Q. Fei, X. Hu, C. Wu, and N. Li. 2003. Association between single nucleotide polymorphisms of the chicken growth hormone gene and chicken growth and carcass traits. Sci. Bull. Sin. 48:1304-1307. crossref(new window)

Zhang, C., W. Zhang, H. Luo, W. Yue, M. Gao, and Z. Jia. 2008. A new single nucleotide polymorphism in the IGF-I gene and its association with growth traits in the Nanjiang Huang goat. Asian Australas. J. Anim. Sci. 21:1073-1079. crossref(new window)

Zhou, H., A. D. Mitchell, J. P. McMurtry, C. M. Ashwell, and S. J. Lamont. 2005. Insulin-like growth factor-I gene polymorphism associations with growth, body composition, skeleton integrity, and metabolic traits in chickens. Poult. Sci. 84:212-219. crossref(new window)