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Electrochemical Detection of Self-Assembled Viologen Modified Electrode as Mediator of Glucose Sensor
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 Title & Authors
Electrochemical Detection of Self-Assembled Viologen Modified Electrode as Mediator of Glucose Sensor
Lee, Dong-Yun; Choi, Won-Suk; Park, Sang-Hyun; Kwon, Young-Soo;
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An amperometric glucose biosensor has been developed using viologen derivatives as a charge transfer mediator between a glucose oxidase (GOD) and a gold electrode. A highly stable self-assembled monolayer (SAM) of thiol-based viologen was immobilized onto the gold electrode of a quartz crystal microbalance (QCM) and GOD was immobilized onto the viologen modified electrode. This biosensor response to glucose was evaluated amperometrically in the potential of -300mV. Upon immobilization of the glucose oxidase onto the viologen modified electrode, the biosensor showed rapid response towards glucose. Experimental conditions influencing the biosensor performance, such as pH potential, were optimized and assessed. This biosensor offered excellent electrochemical responses for glucose concentration below mol level with high sensitivity and selectivity and short response time. The levels of the RSDs (<5%) for the entire analyses reflected the highly reproducible sensor performance. A linear calibration range between the current and the glucose concentration was obtained up to . The detection limit was determined to be .
Glucose Biosensor;Viologen;Mediator;Glucose Oxidase;Detection Limit;
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Self-assembled monolayers (SAMs) for electrochemical sensing, Journal of Solid State Electrochemistry, 2011, 15, 7-8, 1535  crossref(new windwow)
Electrochemical detection of hydrogen peroxide via hemoglobin–DNA/pyterpy-modified gold electrode, Current Applied Physics, 2009, 9, 4, e232  crossref(new windwow)
L. Clark and C. Lyons, 'Electrode systems for continuous monitoring cardiovascular surgεry', Ann. NY Acad. Sci. 102 (1962) 29 crossref(new window)

S. J. Updike and J. P. Hicks, 'The enzyme electrode', Nature, 214 (1967) 986 crossref(new window)

N. Nakamura, H.-X. Huang, D.-J. Qian and J Miyake, 'Quartz Crystal Microbalance and Electrochemical Studies on a Viologen Thiol Incorporated in Phospholipid Self-Assembled Monolayers', Langmuir, 18 (2002) 5804 crossref(new window)

D.-Y. Lee, A.K.M. Kafi, S.-H. Park, D.-J. Qian, Y. -S. Kwon, 'Influence of Anions on Electrochemical Redox Reaction and Electrical Property using Violgen Derivative', Jpn. J. Appl. Phys. 45 (4B) (2006) 3772 crossref(new window)

D.-Y. Lee, A.K.M. Kafi, S.-H. Park, Y. -S. Kwon, 'Charge Transfer Property of Self-Assembled Viologen Derivative by Electrochemical Quartz Crystal Microbalance Response', J. Nanosci. Nanotechnol., 6 (2006) 3657 crossref(new window)

A.K.M. Kafi, D.-Y. Lee, S.-H. Park, Y. -S. Kwon, 'Development of a peroxide biosensor made of a thiolated-viologen and hemoglobin-modified gold electrode', Microchem. J., 85 (2007) 308 crossref(new window)

J.-Y. Ock, H.-K. Shin, Y. -S. Kwon, J. Miyake, 'Study on the electrochemical behavior of thε viologen monolayεrs by different chεmical structure', Colloid. Surface. A, 257 (2005) 351 crossref(new window)

D.-Y. Lee, W.-S. Choi, A.K.M. Kafi, S.-H. Park, Y. -S. Kwon, 'Immobilization, Hybridization and Amperometric Detection of DNA Sensor Using Quartz Crystal Microbalance', J. Nanosci. Nanotechnol. , 8 (2008) 4553 crossref(new window)

S. Hu, C.-C. Liu, 'Development of a hypoxanthine biosensor based on immobilized xanthine oxidase chemically modified electrode', Electroanal., 9 (1997) 372 crossref(new window)

M. E. Ghica, Christopher M. A. Brett, 'A glucose biosensor using methyl viologen redox mεdiator on carbon film electrodes', Anal. Chim. Acta, 532 (2005) 145 crossref(new window)

A.K.M. Kafi, F. Yin, H.-K. Shin, Y.-S. Kwon, 'Hydrogen peroxide biosensor based on DNA-Hb modified gold electrode', Thin Solid Films, 499 (2006) 420 crossref(new window)

A. I. Yaropolov, S. V. Shleev, O. V. Morozova, E. A. Zaitseva, G. Marko-Varga, J. Enmeus, L. Gorton, 'An Amperomεtric Biosensor Based on Laccase Immobilized in Polymer Matrices for Determining Phenolic Compounds', J. Anal. Chem. , 60 (2005) 553 crossref(new window)