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Hot Water Extract of Leather Carp (Cyprinus carpio nudus) Improves Exercise Performance in Mice
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  • Journal title : Preventive Nutrition and Food Science
  • Volume 20, Issue 4,  2015, pp.246-252
  • Publisher : The Korean Society of Food Science and Nutrition
  • DOI : 10.3746/pnf.2015.20.4.246
 Title & Authors
Hot Water Extract of Leather Carp (Cyprinus carpio nudus) Improves Exercise Performance in Mice
Lee, Gong-Hyeon; Harwanto, Dicky; Park, Sun-Mee; Choi, Jae-Suk; Kim, Mi-Ryung; Hong, Yong-Ki;
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The hot water extract of leather carp (Cyprinus carpio nudus) has been used as a nourishing tonic soup and as an aid for recovery from physical fatigue. In this study, we investigated the effect of leather carp extract on exercise performance in mice. Swimming endurance and forelimb grip strength were assessed following oral administration of the extract (once per day for 7 days) at a dose of body weight. After 7 days, mice given the leather carp extract had significantly greater swimming endurance [ (P<0.05); 52% longer than day 0] and forelimb grip strength [ Newton (P<0.01); 17% greater than day 0]. The extract increased muscle mass, but had little effect on body weight. Following the swimming exercise, blood glucose, glutathione peroxidase, and superoxide dismutase levels in extract-fed mice were significantly higher (145%, 131%, and 106%, respectively) than in the saline control group. Blood levels of high-density lipoprotein cholesterol were also significantly increased (128%) in mice given the extract compared to the controls. These results suggest that leather carp extract can improve physical exercise performance and prevent oxidative stress caused by exhaustive workouts.
anti-fatigue;exercise performance;leather carp (Cyprinus carpio nudus);
 Cited by
Pathogenic microorganisms, heavy metals, and antibiotic residues in seven Korean freshwater aquaculture species,;;;;;;;

Food Science and Biotechnology, 2016. vol.25. 5, pp.1469-1476 crossref(new window)
Pathogenic microorganisms, heavy metals, and antibiotic residues in seven Korean freshwater aquaculture species, Food Science and Biotechnology, 2016, 25, 5, 1469  crossref(new windwow)
Tucker CS. 2000. Off-flavor problems in aquaculture. Rev Fish Sci 8: 45-88. crossref(new window)

Doopedia. 2015. Leather carp. (accessed April 30, 2015).

KFS. 2014. Korean fisheries yearbook. Korea Fisheries Association, Seoul, Korea. p 531.

Mehta RK, Agnew MJ. 2012. Influence of mental workload on muscle endurance, fatigue, and recovery during intermittent static work. Eur J Appl Physiol 112: 2891-2902. crossref(new window)

Marquez R, Santangelo G, Sastre J, Goldschmidt P, Luyckx J, Pallardo FV, Vina J. 2001. Cyanoside chloride and chromocarbe diethylamine are more effective than vitamin C against exercise-induced oxidative stress. Pharmacol Toxicol 89: 255-328. crossref(new window)

An HJ, Choi HM, Park HS, Han JG, Lee EH, Park YS, Um JY, Hong SH, Kim HM. 2006. Oral administration of hot water extracts of Chlorella vulgaris increases physical stamina in mice. Ann Nutr Metab 50: 380-386. crossref(new window)

Jung KA, Han D, Kwon EK, Lee CH, Kim YE. 2007. Antifatigue effect of Rubus coreanus Miquel extract in mice. J Med Food 10: 689-693. crossref(new window)

Yu B, Lu ZX, Bie XM, Lu FX, Huang XQ. 2008. Scavenging and anti-fatigue activity of fermented defatted soybean peptides. Eur Food Res Technol 226: 415-421. crossref(new window)

Yu F, Lu S, Yu F, Feng S, McGuire PM, Li R, Wang R. 2006. Protective effects of polysaccharide from Euphorbia kansui (Euphorbiaceae) on the swimming exercise-induced oxidative stress in mice. Can J Physiol Pharmacol 84: 1071-1079. crossref(new window)

Wang J, Li S, Fan Y, Chen Y, Liu D, Cheng H, Gao X, Zhou Y. 2010. Anti-fatigue activity of the water-soluble polysaccharides isolated from Panax ginseng C. A. Meyer. J Ethnopharmacol 130: 421-423. crossref(new window)

Ni W, Gao T, Wang H, Du Y, Li J, Li C, Wei L, Bi H. 2013. Anti-fatigue activity of polysaccharides from the fruits of four Tibetan plateau indigenous medicinal plants. J Ethnopharmacol 150: 529-535. crossref(new window)

Yu FR, Liu Y, Cui YZ, Chan EQ, Xie MR, McGuire PP, Yu FH. 2010. Effects of a flavonoid extract from Cynomorium songaricum on the swimming endurance of rats. Am J Chin Med 38: 65-73. crossref(new window)

Huang CC, Hsu MC, Huang WC, Yang HR, Hou CC. 2012. Triterpenoid-rich extract from Antrodia camphorata improves physical fatigue and exercise performance in mice. Evid Based Complement Alternat Med 2012: 364741.

Ren J, Zhao M, Wang H, Cui C, You L. 2011. Effects of supplementation with grass carp protein versus peptide on swimming endurance in mice. Nutrition 27: 789-795. crossref(new window)

Wang L, Zhang HL, Lu R, Zhou YJ, Ma R, Lv JQ, Li XL, Chen LJ, Yao Z. 2008. The decapeptide CMS001 enhances swimming endurance in mice. Peptides 29: 1176-1182. crossref(new window)

Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. 1951. Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275.

Kim JH, Jung WS, Bae GS, Heo HJ, Kim DO, Yoon JA, Kim S, Kim YJ. 2010. Short-term synergistic effect of fruit extracts with red-ginseng on forced swimming endurance capacity in ICR mice. Food Sci Biotechnol 19: 267-270. crossref(new window)

Li X, Mohan S, Gu W, Wergedal J, Baylink DJ. 2001. Quantitative assessment of forearm muscle size, forelimb grip strength, forearm bone mineral density, and forearm bone size in determining humerus breaking strength in 10 inbred strains of mice. Calcif Tissue Int 68: 365-369. crossref(new window)

Golde WT, Gollobin P, Rodriguez LL. 2005. A rapid, simple, and humane method for submandibular bleeding of mice using a lancet. Lab Anim 34: 39-43.

Ahn BM. 2001. The raw biles of grass carp, common carp, and Israeli carp. Kor J Hepatol 7: 131-133.

Choi JH, Rhim CH, Choi YJ, Park KD, Oh SK. 1985. Comparative study on amino acid profiles of wild and cultured carp, and Israeli carp. Bull Korean Fish Soc 18: 545-549.

Young VR, Pellett PL. 1994. Plant proteins in relation to human protein and amino acid nutrition. Am J Clin Nutr 59: 1203S-1212S. crossref(new window)

Chen HM, Muramoto K, Yamauchi F, Nokihara K. 1996. Antioxidant activity of designed peptides based on the antioxidative peptide isolated from digests of a soybean protein. J Agric Food Chem 44: 2619-2623. crossref(new window)

Elias RJ, Kellerby SS, Decker EA. 2008. Antioxidant activity of proteins and peptides. Crit Rev Food Sci Nutr 48: 430-441. crossref(new window)

Kim MR. 2014. Development of high value material and bioactive components from freshwater fish. A report submitted to the Korea Institute of Marine Science and Technology Promotion, Seoul, Korea. p 201.

Dong S, Zeng M, Wang D, Liu Z, Zhao Y, Yang H. 2008. Antioxidant and biochemical properties of protein hydrolysates prepared from silver carp (Hypophthalmichthys molitrix). Food Chem 107: 1485-1493. crossref(new window)

You L, Zhao M, Cui C, Zhao H, Yang B. 2009. Effect of degree of hydrolysis on the antioxidant activity of loach (Misgurnus anguillicaudatus) protein hydrolysates. Innovative Food Sci Emerging Technol 10: 235-240. crossref(new window)

Saggu S, Kumar R. 2008. Effect of seabuckthorn leaf extracts on circulating energy fuels, lipid peroxidation and antioxidant parameters in rats during exposure to cold, hypoxia and restraint (C-H-R) stress and post stress recovery. Phytomedicine 15: 437-446. crossref(new window)

Garrett RH, Grisham CM. 2005. Biochemistry. 3rd ed. Thomson Brooks/Cole, Belmont, CA, USA. p 1086.

Mason RP, Jacob RF. 2015. Eicosapentaenoic acid inhibits glucose-induced membrane cholesterol crystalline domain formation through a potent antioxidant mechanism. Biochim Biophys Acta-Biomembr 1848: 502-509. crossref(new window)

Kumar GP, Anand T, Singsit D, Khanum F, Anilakumar KR. 2013. Evaluation of antioxidant and anti-fatigue properties of Trigonella foenum-graecum L. in rats subjected to weight loaded forced swim test. Pharmacogn J 5: 66-71. crossref(new window)

Wu CY, Chen R, Wang XS, Shen B, Yue W, Wu Q. 2013. Antioxidant and anti-fatigue activities of phenolic extract from the seed coat of Euryale ferox Salisb. and identification of three phenolic compounds by LC-ESI-MS/MS. Molecules 18: 11003-11021. crossref(new window)

Cai Q, Rahn RO, Zhang R. 1997. Dietary flavonoids, quercetin, luteolin and genistein, reduce oxidative DNA damage and lipid peroxidation and quench free radicals. Cancer Lett 119: 99-107. crossref(new window)

Kotosai M, Shimada S, Kanda M, Matsuda N, Sekido K, Shimizu Y, Tokumura A, Nakamura T, Murota K, Kawai Y, Terao J. 2013. Plasma HDL reduces nonesterified fatty acid hydroperoxides originating from oxidized LDL: a mechanism for its antioxidant ability. Lipids 48: 569-578. crossref(new window)

Drew BG, Duffy SJ, Formosa MF, Natoli AK, Henstridge DC, Penfold SA, Thomas WG, Mukhamedova N, de Courten B, Forbes JM, Yap FY, Kaye DM, van Hall G, Febbraio MA, Kemp BE, Sviridov D, Steinberg GR, Kingwell BA. 2009. High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes mellitus. Circulation 119: 2103-2111. crossref(new window)

Fryirs MA, Barter PJ, Appavoo M, Tuch BE, Tabet F, Heather AK, Rye KA. 2010. Effects of high-density lipoproteins on pancreatic ${\beta}$-cell insulin secretion. Arterioscler Thromb Vasc Biol 30: 1642-1648. crossref(new window)

Chapman MJ. 2006. Therapeutic elevation of HDL-cholesterol to prevent atherosclerosis and coronary heart disease. Pharmacol Ther 111: 893-908. crossref(new window)

Bazzano LA, Li TY, Joshipura KJ, Hu FB. 2008. Intake of fruit, vegetables, and fruit juices and risk of diabetes in women. Diabetes Care 31: 1311-1317. crossref(new window)

Mirmiran P, Noori N, Zavareh MB, Azizi F. 2009. Fruit and vegetable consumption and risk factors for cardiovascular disease. Metabolism 58: 460-468. crossref(new window)

Gaziano JM, Hennekens CH, O'Donnell CJ, Breslow JL, Buring JE. 1997. Fasting triglycerides, high-density lipoprotein, and risk of myocardial infarction. Circulation 96: 2520-2525. crossref(new window)