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Tectona grandis Callus Produces Antibacterial Triterpene Acids Not Detected in the Intact Plant
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  • Journal title : Natural Product Sciences
  • Volume 3, Issue 1,  1997, pp.75-80
  • Publisher : The Korean Society of Pharmacognosy
  • DOI :
 Title & Authors
Tectona grandis Callus Produces Antibacterial Triterpene Acids Not Detected in the Intact Plant
Marwani, Erly; Kobayashi, Akio; Kajiyama, Shin-ichiro; Fukusaki, Eiichiro; Nitoda, Teruhiko; Kanzaki, Hiroshi; Kawazu, Kazuyoshi;
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 Abstract
Preliminary antibacterial assay data that the Tectona grandis callus extract showed more antibacterial activity against E. coli and B. subtilis than the leaf extract led the authors to isolate the following antibacterial compounds from the callus. A mixture (3) of acid (3a) and acid (3b) exhibited the most potent antibacterial activity against both bacteria. The other 3 compounds, in the decreasing order of the activity, were identified as acid (2), betulinic acid (1), and ,23-trihydroxy-urs-12-en-28-oic acid (4). The antibacterial compounds (2, 3a, 3b and 4) were not detected or occurring in small quantities in the intact tissue, while they were observed in the callus. Only the less active compound 1 was present more abundantly in intact tissues than the callus.
 Keywords
Tectona grandis callus;triterpene acids;antibacterial compounds;oleanene;lupene;ursene;
 Language
English
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