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Stabilization of Compact Protein Structures by Macrocyclic Hosts Cucurbit[n]urils in the Gas Phase
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  • Journal title : Mass Spectrometry Letters
  • Volume 7, Issue 1,  2016, pp.16-20
  • Publisher : Korean Society Mass Spectrometry
  • DOI : 10.5478/MSL.2016.7.1.16
 Title & Authors
Stabilization of Compact Protein Structures by Macrocyclic Hosts Cucurbit[n]urils in the Gas Phase
Lee, Jong Wha; Park, Mi Hyun; Ju, Jeong Tae; Choi, Yun Seop; Hwang, Soo Min; Jung, Dong Jin; Kim, Hugh I.;
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Characterization of intact protein structures in the gas phase using electrospray ionization combined with ion mobility mass spectrometry has become an important tool of research. However, the biophysical properties that govern the structures of protein ions in the gas phase remain to be understood. Here, we investigated the impact of host-guest complexation of ubiquitin (Ubq) with macrocyclic host molecules, cucurbit[n]urils (CB[n]s, n
ion mobility mass spectrometry;cucurbit[n]uril;ubiquitin;host-guest chemistry;
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