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Synthesis and the Absolute Configurations of Isoflavanone Enantiomers
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 Title & Authors
Synthesis and the Absolute Configurations of Isoflavanone Enantiomers
Won, Dong-Ho; Shin, Bok-Kyu; Han, Jae-Hong;
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 Abstract
Isoflavanone has been synthesized from the reduction of isoflavone in nearly quantitative yield. Isoflavone with seven equivalents of ammonium formate in the presence of Pd/C in ethanol under atmosphere exclusively produced the two-electron reduced product in two hours. It was characterized by various spectroscopic methods, including UV-VIS, EI-MS, -NMR, -NMR and , -COSY. The racemic mixture was separated by Sumi-Chiral column chromatography and the absolute configurations of the enantiomers were characterized by circular dichroism spectroscopy.
 Keywords
absolute configuration;circular dichroism (CD);flavonoids;isoflavanone;palladium on activated carbon (Pd/C);
 Language
English
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