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Citrus Peel Wastes as Functional Materials for Cosmeceuticals
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 Title & Authors
Citrus Peel Wastes as Functional Materials for Cosmeceuticals
Kim, Sang-Suk; Lee, Jung-A; Kim, Ji-Young; Lee, Nam-Ho; Hyun, Chang-Gu;
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 Abstract
The suitability of CPWs, by-products of the juice industry, was investigated as a source for the production of cosmeceuticals. Four kinds of CPWs, CW, CWE, CWER, and CWEA, were examined for their antioxidant potentials in terms of DPPH radical-scavenging ability for anti-wrinkle applications, inhibition of tyrosinase or melanin production for whitening products, and anti-inflammatory effects to treat various skin diseases such as atopic dermatitis and acne as well as for anti-bacterial activity against acne-inducing pathogens. Of the four extracts, CWER was the most potent tyrosinase inhibitor ( value: ), and CWEA () showed good antioxidative effects. CWE and CWEA samples had dose-dependent inhibitory effects on the melanin production. The cytotoxic effects of the four CPWs were determined by colorimetric MTT assays using human keratinocyte HaCaT cells. Most extracts exhibited low cytotoxicity at . These results suggest CPWs are attractive candidates for topical applications on the human skin.
 Keywords
acid lysis;acne;citrus peel waste;DPPH;interleukin-8;melanin;tumor necrosis factor ;
 Language
English
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