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Diels-Alder type adducts from the fruits of Morus alba L.
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 Title & Authors
Diels-Alder type adducts from the fruits of Morus alba L.
Lee, Yeong-Geun; Seo, Kyeong-Hwa; Hong, Eock-Kee; Kim, Dong-Man; Kim, Young-Eon; Baek, Nam-In;
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 Abstract
The fruits of Morus alba L. were extracted with 80 % aqueous MeOH, and the concentrated extract was partitioned into EtOAc, n-butyl alcohol, and water fractions. The repeated silica gel () and octadecyl silica gel column chromatographies for the EtOAc and n-butyl alcohol fractions led to isolation of two phenolic compounds. The chemical structures of the compounds were determined as Diels-Alder type adducts, mulberrofuran E (1) and chalcomoracin (2) based on spectroscopic data analyses including nuclear magnetic resonance, mass spectrometry, and infrared spectrometry. Compounds 1 and 2 were isolated for the first time from the fruits of M. alba L. in this study.
 Keywords
Chalcomoracin;Diels-Alder adduct;Morus alba fruit;mulberrofuran E;
 Language
Korean
 Cited by
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꽃송이버섯(Sparassis crispa) 자실체로부터 ergosteol peroxide의 분리 및 동정,이영근;;김형근;이대영;이승은;김금숙;백남인;

Journal of Applied Biological Chemistry, 2016. vol.59. 4, pp.313-316 crossref(new window)
2.
국화(Chrysanthemum morifolium)꽃으로부터 Flavonoid의 분리 및 동정,김형근;고정환;이영근;박하승;김동찬;손국성;백윤수;권오근;신학기;백남인;

Journal of Applied Biological Chemistry, 2016. vol.59. 4, pp.357-360 crossref(new window)
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Ergosterol peroxides from the fruit body of Sparassis crispa, Journal of Applied Biological Chemistry, 2016, 59, 4, 313  crossref(new windwow)
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Flavonoids from the flower of Chrysanthemum morifolium, Journal of Applied Biological Chemistry, 2016, 59, 4, 357  crossref(new windwow)
 References
1.
Andallua B, Suryakanthama V, Srikanthia BL, Reddy GK (2001) Effect of mulberry (Morus indica L.) therapy on plasma and erythrocyte membrane lipids in patients with type 2 diabetes. Clin Chim Acta 314: 47-53 crossref(new window)

2.
Cui X, Wang H, Liu C, Chen R (2008) study of anti-oxidant phenolic compounds from stem barks of Morus yananensis. China J Chinese Mater Med 33: 1569-1572

3.
Dat NT, Binh PTX, Quynh LTP, Minh CV, Huong HT, Lee JJ (2010) Cytotoxic prenylated flavonoids from Morus alba. Fitoterapia 81: 1224-1227 crossref(new window)

4.
Du Q, Zheng J, Xu Y (2008) Composition of anthocyanins in mulberry and their antioxidant activity. J. Food Compos. Anal 21: 390-395 crossref(new window)

5.
Fontecave M, Lepoivre M, Elleingand E, Gerez C, Guittet O (1998) Resveratrol, a remarkable inhibitor of ribonucleotide reductase. FEBS Lett 421: 277-279 crossref(new window)

6.
Fremont L, Belguendou L, Delpal S (1999) Antioxidant activity of resveratrol and alcohol-free wine polyphenols realted to LDL oxidation and polyunsaturated fatty acids. Life Sci 64: 2511-2521 crossref(new window)

7.
Jun HI, Kim YA, Kim YS (2014) Antioxidant activities of Rubus coreanus Miquel and Morus alba L. Fruits. J Korean Soc Food Sci Nutr 43: 381-388 crossref(new window)

8.
Kim HB, Kim SL (2003a) Quanitification and varietal variation of rutin in mulberry fruits. Korean J Seric Sci 46: 1-5

9.
Kim HB, Sung KB, Nam HW, Chang SJ, Kim SL, Moon JY (2003b) Quanitification and varietal variation of fatty acids in mulberry fruits. Korean J Seric Sci 45: 75-79

10.
Kim YJ, Sohn MJ, Kim WG (2012) Chalcomoracin and moracin C, new inhibitors of Staphylococcus aureus enoyl-acyl carrier protein reductase from Morus alba. Biol Pharm Bull 35: 791-795 crossref(new window)

11.
Lee GC, Chung HM (1999) A literature review on the origin and the culinary characteristics of Dasik. J Korean Soc Food Cul 14: 395-403

12.
Lee HS, Sur EY, Kim WK (2004a) Resveratrol induces apoptosis in SW480 human colon cancer cell lines. Food Sci Biotechnol 13: 80-84

13.
Lee JI, Lee JD, Ha YJ, Jung JD, Lee JW, Lee JR, Kwack SJ, Kim DH, Do CH (2004b) Effect of dietary silkworm droppings on chemical composition of pork loin. J Anim Sci Technol 46: 1013-1022 crossref(new window)

14.
Lim HH, Lee SO, Kim SY, Yang SJ, Lim Y (2013) Anti-inflammatory and antiobesity effects of mulberry leaf and fruit extract on high fat diet-induced obesity. Exp Biol Med 238: 1160-1169 crossref(new window)

15.
Lim HS, Ha HK, Lee HY, Lee JK, Lee MY, Shin HK (2014) Morus alba L. suppresses the development of atopic dermatitis induced by the house dust mite in NC/Nga mice. BMC Complement Alt Med 14: 139 crossref(new window)

16.
Park YS, Kang SS, Choi HJ, Yang SJ, Shon HH, Seo HH, Jeong JJ (2014) Effect of mulberry (Morus alba L.) extract on blood flow improvement. J Korean Soc Food Sci Nutr 43: 498-506 crossref(new window)

17.
Sun F, Shen L, Ma Z (2011) Screening for ligands of human aromatase from mulberry (Mori alba L.) leaf by using high-performance liquid chromatography/tandem mass spectrometry. Food Chem 126: 1337-1343 crossref(new window)

18.
Yang Z, Wang Y, Wang Y, Zhang Y (2012) Bioassay-guided screening and isolation of ${\alpha}$-glucosidase and tyrosinase inhibitors from leaves of Morus alba. Food Chem 131: 617-625 crossref(new window)

19.
Zhang QJ, Tang YB, Chen RY, Yu DQ (2007) Three new cytotoxic Diels-Aldertype adducts from Morus australis. Chem Biodiverse 4: 1533-1540 crossref(new window)