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Antifungal Effect of Chitosan as Ca2+ Channel Blocker
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  • Journal title : The Plant Pathology Journal
  • Volume 32, Issue 3,  2016, pp.242-250
  • Publisher : Korean Society of Plant Pathology
  • DOI : 10.5423/PPJ.OA.08.2015.0162
 Title & Authors
Antifungal Effect of Chitosan as Ca2+ Channel Blocker
Lee, Choon Geun; Koo, Ja Choon; Park, Jae Kweon;
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 Abstract
The aim of this study was to investigate antifungal activity of a range of different molecular weight (MW) chitosan against Penicillium italicum. Our results demonstrate that the antifungal activity was dependent both the MW and concentration of the chitosan. Among a series of chitosan derived from the hydrolysis of high MW chitosan, the fractions containing various sizes of chitosan ranging from 3 to 15 glucosamine units named as chitooligomers-F2 (CO-F2) was found to show the highest antifungal activity against P. italicum. Furthermore, the effect of CO-F2 toward this fungus was significantly reduced in the presence of , whereas its effect was recovered by ethylenediaminetetraacetic acid, suggesting that the CO-F2 acts via disruption of gradient required for survival of the fungus. Our results suggest that CO-F2 may serve as potential compounds to develop alternatives to synthetic fungicides for the control of the postharvest diseases.
 Keywords
antifungal activity; channel;chitosan;molecular weight;Penicillium italicum;
 Language
English
 Cited by
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