Confounding of Time Trend with Dropout Process in Longitudinal Data Analysis Kim, Ji-Hyun; Choi, Hye-Hyun;
In longitudinal studies, outcomes are repeatedly measured over time for each subject. It is common to have missing values or dropouts for longitudinal data. In this study time trend in longitudinal data with dropouts is of concern. The confounding of time trend with dropout process is investigated through simulation studies. Some simulation results are reported for binary responses as well as continuous responses with patterns of dropouts varying. It has been found that time trend is not confounded with random dropout process for binary responses when it is estimated using GEE.