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Nonparametric Procedure for Identifying the Minimum Effective Dose with Ordinal Response Data
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 Title & Authors
Nonparametric Procedure for Identifying the Minimum Effective Dose with Ordinal Response Data
Kang, Jongsook; Kim, Dongjae;
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The primary interest of drug development studies is identifying the lowest dose level producing a desirable effect over that of the zero-dose control, which is referred as the minimum effective dose (MED). In this paper, we suggest a nonparametric procedure for identifying the MED with binary or ordered categorical response data. Proposed test and Williams' test are compared by Monte Carlo simulation study and discussed.
Binary response;Minimum effective dose (MED);Nonparametric test;Monte Carlo study;Ordinal response;
 Cited by
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