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A Bayesian Multiple Testing of Detecting Differentially Expressed Genes in Two-sample Comparison Problem
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 Title & Authors
A Bayesian Multiple Testing of Detecting Differentially Expressed Genes in Two-sample Comparison Problem
Oh Hyun-Sook; Yang Wan-Youn;
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 Abstract
The Bayesian approach to multiple testing procedure for one sample testing problem proposed by Scott and Berger (2003) is extended to two-sample comparison problem in microarray experiments. The prior distribution of each gene`s mean for one sample is given conditionally on the corresponding gene`s mean for the other sample. Posterior distributions of interesting parameters are derived and estimated based on an importance sampling method. A simulated example is given for illustration.
 Keywords
microarray experiment;Bayesian multiple testing;importance sampling method;
 Language
English
 Cited by
 References
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